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View Structure Prediction Details

Protein: endoB-PA
Organism: Drosophila melanogaster
Length: 390 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for endoB-PA.

Description E-value Query
Range
Subject
Range
gi|50510503 - gi|50510503|dbj|BAD32237.1| mKIAA0491 protein [Mus musculus]
251.0 [0..3] [383..32]

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Predicted Domain #1
Region A:
Residues: [1-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNINLPNFNV KNLVKEAGST ISRVVQLTEE KLGTTERTEY DLHFQNLAER ADVTKTWTEK  60
   61 IVRDTESVLI PNPQNRVEDF IFEKIEKSKP KRLSNLEHLA LDMIEAGGDF GQDLPYGQAL 120
  121 IKVGQAEQKL GQCEHDFIAT SGICFTQPLR KFLDGEMKTI GKERGILETK RLDLDACKNR 180
  181 VKKARSMLGQ QSKDGISPEA VLEQAERDLR VAQAEFDRQA EITKLLLDGI STSQASHLRH 240
  241 LHAFIQTQVR YYKQCGDVME QLQRELA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.0
Match: 1zwwA
Description: Crystal structure of endophilin-A1 BAR domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.92353432746981 bayes_pls_golite062009
binding 2.43584893484993 bayes_pls_golite062009
lysophosphatidic acid acyltransferase activity 1.43515660906576 bayes_pls_golite062009
signal transducer activity 1.15315260510573 bayes_pls_golite062009
molecular transducer activity 1.15315260510573 bayes_pls_golite062009
identical protein binding 0.652723321884221 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.127423274812986 bayes_pls_golite062009
cytoskeletal protein binding 0.11971814425029 bayes_pls_golite062009
pyrophosphatase activity 0.0898200140309309 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0808236947742297 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0782188789090384 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [268-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLGGPTPYIP LDVNEASASK SNISSGAAAR GPGNNHSANM AATGHKPNQP MHVSTDQMQR  60
   61 ARVLCSYDAK DHTELNLSAN EVIFVTECSP VNEDYMYGKQ GLLKGLVPRA FVEMLDEEHD 120
  121 VTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 1griA
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 3.13677730481089 bayes_pls_golite062009
binding 2.63972476345585 bayes_pls_golite062009
cytoskeletal protein binding 1.67112127425228 bayes_pls_golite062009
signal transducer activity 1.34867629228264 bayes_pls_golite062009
molecular transducer activity 1.34867629228264 bayes_pls_golite062009
transporter activity 1.30447542854757 bayes_pls_golite062009
transmembrane transporter activity 1.08558010881058 bayes_pls_golite062009
actin binding 0.75525840382431 bayes_pls_golite062009
substrate-specific transporter activity 0.566172161499832 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.325817349097199 bayes_pls_golite062009
structural molecule activity 0.236653863910566 bayes_pls_golite062009
receptor binding 0.0742205785215131 bayes_pls_golite062009
ion transmembrane transporter activity 0.00508584255499911 bayes_pls_golite062009

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