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View Structure Prediction Details

Protein: Dip3-PA
Organism: Drosophila melanogaster
Length: 348 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dip3-PA.

Description E-value Query
Range
Subject
Range
gi|6934288 - gi|6934288|gb|AAF31700.1|AF218860_1 Dorsal interacting protein 3 [Drosophila melanogaster]
255.0 [0..1] [348..1]

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Predicted Domain #1
Region A:
Residues: [1-145]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRKNGNQDT FPKTEKMQRY YAERETTGPE FDDRLIKLVR ANPAIYDVSH PHYRRNPVRV  60
   61 DIWDRIANEL GASSRFLQTK WKNIRYNYLQ EVKAIETGQA NPNVRKRRFT EDLSFLQNTA 120
  121 QTYNVKKSQS YVAQQNGMGS DNDSN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.955
Match: 2cqqA
Description: Solution Structure of RSGI RUH-037, a myb DNA-binding domain in human cDNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.86538715425734 bayes_pls_golite062009
DNA binding 4.40186699787632 bayes_pls_golite062009
nucleic acid binding 3.98153794570167 bayes_pls_golite062009
transcription factor activity 3.78935192723648 bayes_pls_golite062009
sequence-specific DNA binding 3.25454589469681 bayes_pls_golite062009
transcription activator activity 2.92652250400688 bayes_pls_golite062009
binding 2.92574888336072 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.00875399167309 bayes_pls_golite062009
protein binding 1.84594855626241 bayes_pls_golite062009
transcription repressor activity 1.69615348178304 bayes_pls_golite062009
transcription factor binding 1.24678737091956 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.865913662624162 bayes_pls_golite062009
transcription cofactor activity 0.691780246385357 bayes_pls_golite062009
chromatin binding 0.65622150362507 bayes_pls_golite062009
transcription corepressor activity 0.0723215858239072 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [146-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFLYPDPEHL KIDASEGYDI IELDNSDDGS NSDDNEIVPE LQLVMGESKQ QLSLPTTLNG  60
   61 TSSSNHSHEH DQASSPASSP LLTPMVVMGN GYGQEVHLEQ QQTQEQKPFK NSSL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [260-348]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNGEVTIEPI YKPAAIRRAL PSDFLTNPFK RKATQAPLQT QVTSSFNDPI ELYCLSLVDT  60
   61 LRSMRRSERE RVKFEFANIL KDAKYKDES

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle