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View Structure Prediction Details

Protein: Dip3-PA
Organism: Drosophila melanogaster
Length: 348 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dip3-PA.

Description E-value Query
Range
Subject
Range
gi|6934288 - gi|6934288|gb|AAF31700.1|AF218860_1 Dorsal interacting protein 3 [Drosophila melanogaster]
255.0 [0..1] [348..1]

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Predicted Domain #1
Region A:
Residues: [1-145]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRKNGNQDT FPKTEKMQRY YAERETTGPE FDDRLIKLVR ANPAIYDVSH PHYRRNPVRV  60
   61 DIWDRIANEL GASSRFLQTK WKNIRYNYLQ EVKAIETGQA NPNVRKRRFT EDLSFLQNTA 120
  121 QTYNVKKSQS YVAQQNGMGS DNDSN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.955
Match: 2cqqA
Description: Solution Structure of RSGI RUH-037, a myb DNA-binding domain in human cDNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.86538715425734 bayes_pls_golite062009
DNA binding 4.40186699787632 bayes_pls_golite062009
nucleic acid binding 3.98153794570167 bayes_pls_golite062009
transcription factor activity 3.78935192723648 bayes_pls_golite062009
sequence-specific DNA binding 3.25454589469681 bayes_pls_golite062009
transcription activator activity 2.92652250400688 bayes_pls_golite062009
binding 2.92574888336072 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.00875399167309 bayes_pls_golite062009
protein binding 1.84594855626241 bayes_pls_golite062009
transcription repressor activity 1.69615348178304 bayes_pls_golite062009
transcription factor binding 1.24678737091956 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.865913662624162 bayes_pls_golite062009
transcription cofactor activity 0.691780246385357 bayes_pls_golite062009
chromatin binding 0.65622150362507 bayes_pls_golite062009
transcription corepressor activity 0.0723215858239072 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [146-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFLYPDPEHL KIDASEGYDI IELDNSDDGS NSDDNEIVPE LQLVMGESKQ QLSLPTTLNG  60
   61 TSSSNHSHEH DQASSPASSP LLTPMVVMGN GYGQEVHLEQ QQTQEQKPFK NSSL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [260-348]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNGEVTIEPI YKPAAIRRAL PSDFLTNPFK RKATQAPLQT QVTSSFNDPI ELYCLSLVDT  60
   61 LRSMRRSERE RVKFEFANIL KDAKYKDES

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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Created and Maintained by: Michael Riffle