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View Structure Prediction Details

Protein: rhi-PA
Organism: Drosophila melanogaster
Length: 418 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rhi-PA.

Description E-value Query
Range
Subject
Range
gi|63146158 - gi|63146158|gb|AAY33990.1| rhino [Drosophila melanogaster]
277.0 [0..1] [418..1]

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Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRNHQRPNL GLVDAPPNDH VEEYVVEKIL GKRFVNGRPQ VLVKWSGFPN ENNTWEPLEN  60
   61 VGNCMKLVSD FESEVFRLHR KAAAKSVGKS KSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.522879
Match: 2dntA
Description: No description for 2dntA was found.

Predicted functions:

Term Confidence Notes
binding 2.63081545253584 bayes_pls_golite062009
chromatin binding 2.26856644581646 bayes_pls_golite062009
protein binding 1.63976398283458 bayes_pls_golite062009
transcription repressor activity 1.08928222818715 bayes_pls_golite062009
transcription regulator activity 0.627858578903821 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [94-269]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSSSGPLITE NGPSSSKKTQ QHSKSVQAKN TAGMSKMNQK KGKNIKKTAG KIKDIENYPK  60
   61 TQMPSTSQVS TDSTEVFDGN PSATTTNMIK SPRIQSLFSD LNLIEPTKDK DVGDTSLKTP 120
  121 PKSRRLIEFP QREDAPLSSK HVSPMLIRKE SQPLQSSCTD DSDLGESSSS MSLPTV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [270-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSTSSEKSIK VTKSEPKTLG QIKFSSRSSD GGHAASSLGA PKEGDIGLDL SGSDSMDSEV  60
   61 ESMRRCPRRK RKKTYPDWKF PEMTKPFGVN RGLDLDKILH CYQMNDDLFM FVTWKGCSSI 120
  121 DAVHINDIKE AYPLQIIKYF ESLRIIVPK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.0
Match: 1dz1A
Description: Heterochromatin protein 1, HP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.63081545253584 bayes_pls_golite062009
chromatin binding 2.26856644581646 bayes_pls_golite062009
protein binding 1.63976398283458 bayes_pls_golite062009
transcription repressor activity 1.08928222818715 bayes_pls_golite062009
transcription regulator activity 0.627858578903821 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle