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View Structure Prediction Details

Protein: rhi-PA
Organism: Drosophila melanogaster
Length: 418 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rhi-PA.

Description E-value Query
Range
Subject
Range
gi|63146158 - gi|63146158|gb|AAY33990.1| rhino [Drosophila melanogaster]
277.0 [0..1] [418..1]

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Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRNHQRPNL GLVDAPPNDH VEEYVVEKIL GKRFVNGRPQ VLVKWSGFPN ENNTWEPLEN  60
   61 VGNCMKLVSD FESEVFRLHR KAAAKSVGKS KSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.522879
Match: 2dntA
Description: No description for 2dntA was found.

Predicted functions:

Term Confidence Notes
binding 2.63081545253584 bayes_pls_golite062009
chromatin binding 2.26856644581646 bayes_pls_golite062009
protein binding 1.63976398283458 bayes_pls_golite062009
transcription repressor activity 1.08928222818715 bayes_pls_golite062009
transcription regulator activity 0.627858578903821 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [94-269]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSSSGPLITE NGPSSSKKTQ QHSKSVQAKN TAGMSKMNQK KGKNIKKTAG KIKDIENYPK  60
   61 TQMPSTSQVS TDSTEVFDGN PSATTTNMIK SPRIQSLFSD LNLIEPTKDK DVGDTSLKTP 120
  121 PKSRRLIEFP QREDAPLSSK HVSPMLIRKE SQPLQSSCTD DSDLGESSSS MSLPTV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [270-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSTSSEKSIK VTKSEPKTLG QIKFSSRSSD GGHAASSLGA PKEGDIGLDL SGSDSMDSEV  60
   61 ESMRRCPRRK RKKTYPDWKF PEMTKPFGVN RGLDLDKILH CYQMNDDLFM FVTWKGCSSI 120
  121 DAVHINDIKE AYPLQIIKYF ESLRIIVPK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.0
Match: 1dz1A
Description: Heterochromatin protein 1, HP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.63081545253584 bayes_pls_golite062009
chromatin binding 2.26856644581646 bayes_pls_golite062009
protein binding 1.63976398283458 bayes_pls_golite062009
transcription repressor activity 1.08928222818715 bayes_pls_golite062009
transcription regulator activity 0.627858578903821 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle