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View Structure Prediction Details

Protein: spin-PA
Organism: Drosophila melanogaster
Length: 605 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for spin-PA.

Description E-value Query
Range
Subject
Range
spin-PC - The gene spinster is referred to in FlyBase by the symbol Dmel\spin (CG8428, FBgn0086676). It is a p...
288.0 [0..1] [605..1]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLKHQKQSY QPLPTAAAMD NPAMIQSSGS SGSSSSEEGG SREDVANLSP LGLPTTYSSQ  60
   61 QLMPSDTDSM EEERHRLRPH HHHHHPLGEH HHIPG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.01
Match: 2awzA
Description: Hepatitis C Virus NS5b RNA Polymerase in complex with a covalent inhibitor (5h)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [96-605]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPPSAVVPSR LSSVGRSQWF TVTVLCFVNL INYMDRFTIA GVLTDVRNDF DIGNDSAGLL  60
   61 QTVFVISYMV CAPIFGYLGD RYSRPWIMAV GVGLWSTTTL LGSFMKQFGW FIAFRALVGI 120
  121 GEASYSTIAP TIISDLFVHD MRSKMLALFY FAIPVGSGLG YIVGSKTAHL ANDWRWALRV 180
  181 TPILGIVAVF LILLIKDPVR GHSEGSHNLE ATTYKQDIKA LVRNRSFMLS TAGFTCVAFV 240
  241 AGALAWWGPS FIYLGMKMQP GNENIVQDDV AFNFGVITML AGLLGVPLGS FLSQYLVKRY 300
  301 PTADPVICAF GLLVSAPLLT GACLLVNSNS VGTYALIFFG QLALNLNWAI VADILLYVVV 360
  361 PTRRSTAEAF QILISHALGD AGSPYLVGAI SEAIMKHLHK NPSDSGLTTE LRSMSQVAGS 420
  421 AISNATQVIA EATTSLMETA RSSASQEYSD VEQFEGLQYA LFSTSFVEVL GGIFFIFTAC 480
  481 FIIKDKYNAT RGLQDATAQQ QQRDERGQIA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.0
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
binding 1.25550149366993 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle