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View Structure Prediction Details

Protein: ttv-PA, FBpp0305367
Organism: Drosophila melanogaster
Length: 760 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ttv-PA, FBpp0305367.

Description E-value Query
Range
Subject
Range
gi|3435314 - gi|3435314|gb|AAC32397.1| putative tumor suppressor homolog [Drosophila melanogaster]
953.0 [0..1] [760..1]

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Predicted Domain #1
Region A:
Residues: [1-202]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQAKKRYILV FVSCAFLAYA YFGGYRLKVS PLRPRRAQHE SAKDGGVQPH EQLPSFLGAH  60
   61 DMQELQLLQS NQSKSLDSSK HLVTRKPDCR METCFDFTRC YDRFLVYIYP PEPLNSLGAA 120
  121 PPTSANYQKI LTAIQESRYY TSDPTAACLF VLGIDTLDRD SLSEDYVRNV PSRLARLPYW 180
  181 NNGRNHIIFN LYSGTWPDYA EN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [203-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLGFDAGEAI LAKASMGVLQ LRHGFDVSIP LFHKQFPLRA GATGTVQSNN FP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [255-327]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANKKYLLAFK GKRYVHGIGS ETRNSLFHLH NGRDMVLVTT CRHGKSWREL QDNRCDEDNR  60
   61 EYDRYDYETL LQN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [328-446]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STFCLVPRGR RLGSFRFLEA LQAGCIPVLL SNAWVLPFES KIDWKQAAIW ADERLLLQVP  60
   61 DIVRSIPAER IFALRQQTQV LWERYFGSIE KIVFTTFEII RERLPDYPVR SSLVWNSSP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [447-760]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GALLTLPTFA DSSRYMPFLL NSMGAEPRHN YTAVIYVQIG AALGPNAALY KLVRTITKSQ  60
   61 FVERILVLWA ADRPLPLKKR WPPTSHIPLH VISLGGSTRS QGAGPTSQTT EGRPSISQRF 120
  121 LPYDEIQTDA VLSLDEDAIL NTDELDFAYT VWRDFPERIV GYPARAHFWD DSKNAWGYTS 180
  181 KWTNYYSIVL TGAAFYHRYY NYLYTNWLSL LLLKTVQQSS NCEDILMNLL VSHVTRKPPI 240
  241 KVTQRKGYKD RETGRSPWND PDHFIQRQSC LNTFAAVFGY MPLIRSNLRM DPMLYRDPVS 300
  301 NLRKKYRQIE LVGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 89.39794
Match: 1omxA
Description: Alpha-1,4-N-acetylhexosaminyltransferase (Alpha-GalNAcT EXTL2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity, transferring hexosyl groups 4.49413422196176 bayes_pls_golite062009
UDP-glycosyltransferase activity 4.08451171179562 bayes_pls_golite062009
glucuronosyltransferase activity 4.02728111834164 bayes_pls_golite062009
heparan sulfate N-acetylglucosaminyltransferase activity 3.99063852016951 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 3.4614674054855 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 3.19923094610567 bayes_pls_golite062009
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity 3.19489360002767 bayes_pls_golite062009
N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity 2.76301940238613 bayes_pls_golite062009
mannosyltransferase activity 2.61384249067286 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.60650378115696 bayes_pls_golite062009
catalytic activity 1.88676710996045 bayes_pls_golite062009
nucleotidyltransferase activity 1.31793036737589 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.15057449386373 bayes_pls_golite062009
cytidylyltransferase activity 1.14240569193314 bayes_pls_golite062009
glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity 0.999230163117909 bayes_pls_golite062009
protein binding 0.967722609820275 bayes_pls_golite062009
alpha-1,2-mannosyltransferase activity 0.82476668382543 bayes_pls_golite062009
binding 0.667238976803188 bayes_pls_golite062009
transferase activity 0.55272271617052 bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity 0.513376694534047 bayes_pls_golite062009
uridylyltransferase activity 0.321928989676507 bayes_pls_golite062009
mannose-phosphate guanylyltransferase activity 0.2363835251362 bayes_pls_golite062009
UDP-galactosyltransferase activity 0.10185872015123 bayes_pls_golite062009
galactosyltransferase activity 0.0931461042017721 bayes_pls_golite062009
acetylglucosaminyltransferase activity 0.0562130308868509 bayes_pls_golite062009
guanylyltransferase activity 0.0539392112504681 bayes_pls_golite062009
intramolecular oxidoreductase activity 0.0122078907283503 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle