YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Sox15-PA
Organism: Drosophila melanogaster
Length: 784 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Sox15-PA.

Description E-value Query
Range
Subject
Range
gi|66571104 - gi|66571104|gb|AAY51517.1| IP09065p [Drosophila melanogaster]
290.0 [0..1] [784..1]

Back

Predicted Domain #1
Region A:
Residues: [1-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPSYDHEHP HHLLTNYNSK KYPHVSRTPE YSHSTGSDYP EHGGYLTDGR LMHESNSDAG  60
   61 IYHVRQGSEH SSPSLHSPAI QSSGYENEHL NEAVLAAHSH SHSPMPMVSS AYVGGGTASG 120
  121 SLINSNIPLL GGGG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [135-298]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSVLNKFLSH PHAGMVGGGT GQMEDCTSHS PIEAASMWSY DYKGDLCAPN CGYLERHKPL  60
   61 PADLKYRPGG TQSKSAKESR IRRPMNAFMV WAKIERKKLA DENPDLHNAD LSKMLGKKWR 120
  121 SLTPQDRRPY VEEAERLRVI HMTEHPNYKY RPRRRKQSKL RAMQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.69897
Match: 1o4xB
Description: TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA binding 5.15324651287773 bayes_pls_golite062009
transcription regulator activity 4.9607192917135 bayes_pls_golite062009
nucleic acid binding 4.70730250099648 bayes_pls_golite062009
transcription factor activity 3.82658263870186 bayes_pls_golite062009
binding 3.6211482127468 bayes_pls_golite062009
sequence-specific DNA binding 2.96229555092695 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.84606709725198 bayes_pls_golite062009
transcription activator activity 1.62744929149746 bayes_pls_golite062009
transcription repressor activity 1.53825678633232 bayes_pls_golite062009
protein binding 1.131658134984 bayes_pls_golite062009
transcription factor binding 1.10315330167937 bayes_pls_golite062009
DNA bending activity 0.87985209274756 bayes_pls_golite062009
chromatin binding 0.830960835937769 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [299-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGGKEQSESS PNPGTGGSKS NPKLATPPLA TASSSYTTPT DESTCNSTNQ NHGQSTPGGL  60
   61 YEQPLKPTYS PSSVDCYSNA DSTEQIESLA AN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.22
Match: 1pk8A
Description: Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [391-490]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CPPALLNESS PTGGGYDNSL LLKKLTKPSP SRAAKSRQEK LAKSEEKNKG SQSQGQSQQG  60
   61 IYAATYPLAP TSVAVVAARG MYVTCNNRGL LDHGHSVKGT 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [491-614]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FYPPVSVSED DNSTSMRNSI SALQQHCNVV TSTPSSSGGT MPTSEMSSYT VSMADNCGNL  60
   61 RLSMNELSGN EYLPSANAYG MQYEDFLRYQ SNDMDYSTSA VEHKETTSDS ASGQKCLKYP 120
  121 DTNQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.30103
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [615-784]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYDDYEAEAY SNAMLPATAA SYYTQLPYPP TSLAAFPLQL AVPFQQTTSG AYGAQPIQSG  60
   61 YLHYGNYGGY EGMAQSQPQN QAPVHHQQAS HSAPPSLSVP PNQTVTSNSA AISMQQHHHH 120
  121 HFGPAPGMVG VGVGVGVGVG VGEMLFEQQQ RKDDEISNIL AGVRKTCYSN 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.0
Match: 1c82A
Description: Hyaluronate lyase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle