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View Structure Prediction Details

Protein: CG8258-PA
Organism: Drosophila melanogaster
Length: 546 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG8258-PA.

Description E-value Query
Range		 Subject
Range
gi|116754081, gi... - gi|88950858|ref|ZP_01153432.1| Chaperonin Cpn60/TCP-1 [Methanosaeta thermophila PT], gi|88930057|gb|...
 504.0 [0..4] [545..1]

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Predicted Domain #1
Region A:
Residues: [1-546] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALSVPKAPG VSQMLKDGAR MYSGLEEAVF RNISACKEFA QTMRSAYGPN GMNKMIINHI  60
   61 EKQFVTSDAG TIMRELDVEH PAAKLIVMAS QMQDAEVGDG TNFVVVLAGA LLESAEELLR 120
  121 LGITTAEISD GYEKALEKAL EILPNLVSHK IEDYRNVEKV KEVLRTSIMS KQYGQEDFLN 180
  181 DLVSKACVSI LPDEGTFNVD NIRICKILGS GLTKSEVVRG MVFKRFVEGD VTYAEKAKIV 240
  241 IFSCPVDIIQ TETKGTVLIK SADELLSFSS GEESLLESQI KAIADAGVKV VVAGGKVGDM 300
  301 ALHFLNKYGL MAVRLNSKFD LRRLSRSVNA TVLPRITTPS QEELGYCDKV CIEELGDTTI 360
  361 VAFRNEGKDS RIATVVIRGA TDNFMDDIER ALDDAINNFK CLTRDGRYLP GAGATEIELA 420
  421 TQLSAYADTL PGLDQYAVRK FANALEVFPK ALAENSGING TEIVNQLYLA HNNEAGKTIG 480
  481 FDIEAEKAST IDTTKAKLFD LYQSKFWGLK YAVGAAATIL KVDQIIMAKR AGGPKVRQAA 540
  541 GSDDES

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 137.0
Match: 1q3rA
Description: Crystal structure of the chaperonin from Thermococcus strain KS-1 (nucleotide-free form of single mutant)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
unfolded protein binding 9.9038451294995 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 3.6934849790316 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 3.40373598585301 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 3.28982639907979 bayes_pls_golite062009
binding 3.11215702001989 bayes_pls_golite062009
protein binding 2.03574683256805 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.88769858570433 bayes_pls_golite062009
ATPase activity 1.85640607183492 bayes_pls_golite062009
pyrophosphatase activity 1.81343301131567 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.79412354283105 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.79183933227438 bayes_pls_golite062009
nucleic acid binding 1.67284737458957 bayes_pls_golite062009
DNA binding 1.60256620441721 bayes_pls_golite062009
transporter activity 1.27879339110564 bayes_pls_golite062009
transmembrane transporter activity 1.08697283907212 bayes_pls_golite062009
chaperone binding 0.91200031047441 bayes_pls_golite062009
substrate-specific transporter activity 0.828920415160435 bayes_pls_golite062009
hydrolase activity 0.577900060851977 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.573106450426516 bayes_pls_golite062009
ATPase activity, coupled 0.527748436977659 bayes_pls_golite062009
ion transmembrane transporter activity 0.280310103153739 bayes_pls_golite062009
active transmembrane transporter activity 0.275534581026027 bayes_pls_golite062009
hydrogen-exporting ATPase activity, phosphorylative mechanism 0.26275673855778 bayes_pls_golite062009
primary active transmembrane transporter activity 0.252704226951294 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.243984617084631 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.205808843369749 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.202279803135899 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.20198255686005 bayes_pls_golite062009
transferase activity 0.18639662517366 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.16424934648837 bayes_pls_golite062009
catalytic activity 0.107125378994589 bayes_pls_golite062009
kinase activity 0.0871496920547826 bayes_pls_golite062009
cation transmembrane transporter activity 0.0778814959589007 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle