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View Structure Prediction Details

Protein: lectin-29Ca-PA
Organism: Drosophila melanogaster
Length: 236 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lectin-29Ca-PA.

Description E-value Query
Range
Subject
Range
gi|7159330, gi|6... - gi|7159330|gb|AAF37722.1|AF237686_1 MHC class I recognition receptor Ly49I [Mus musculus], gi|675446...
157.0 [0..1] [235..45]
CLC4M_HYLLA - C-type lectin domain family 4 member M OS=Hylobates lar GN=CLEC4M PE=3 SV=1
155.0 [0..11] [233..165]
gi|83405563 - gi|83405563|gb|AAI10615.1| CLEC4M protein [Homo sapiens]
154.0 [0..8] [234..150]
CLC4M_SYMSY - C-type lectin domain family 4 member M OS=Symphalangus syndactylus GN=CLEC4M PE=3 SV=1
153.0 [0..11] [233..188]

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Predicted Domain #1
Region A:
Residues: [1-236]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYKYATCIFS IFALWNFWGV SAKKQDTSTG TNELPKAPMP YYTIENIDMH QQHWFTYNSL  60
   61 RQNGTLWRIG NMEQRLEMRL QSFQNQMETK LRALKQQIEP YMENVKMSNK IKMSVFKKIG 120
  121 SRHFYLEKQK KMPWDSAYDT CRQMGGHLAN ILDEKELNEI FSEETKKKYW VDINSRANDG 180
  181 ASWISTLSGR DVPFLKWKPN LATNIHNHCV YINSNEMYFE NCANDNYFAC QAEQWA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.69897
Match: 1sl6A
Description: Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
carbohydrate binding 2.5043603928753 bayes_pls_golite062009
pattern binding 1.70305894268927 bayes_pls_golite062009
polysaccharide binding 1.64288454942908 bayes_pls_golite062009
glycosaminoglycan binding 1.38067008278151 bayes_pls_golite062009
binding 1.28839159902614 bayes_pls_golite062009
receptor binding 1.12811568960851 bayes_pls_golite062009
sugar binding 0.968405226037797 bayes_pls_golite062009
protein binding 0.603261100926743 bayes_pls_golite062009
extracellular matrix structural constituent 0.30636688317721 bayes_pls_golite062009
receptor activity 0.172562676176019 bayes_pls_golite062009
growth factor activity 0.0253824551299395 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle