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View Structure Prediction Details

Protein: Su(var)205-PB, S...
Organism: Drosophila melanogaster
Length: 206 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Su(var)205-PB, S....

Description E-value Query
Range
Subject
Range
gi|109067205 - gi|109067205|ref|XP_001095397.1| PREDICTED: similar to chromobox homolog 3 [Macaca mulatta]
191.0 [0..3] [206..268]
gi|114666540 - gi|114666540|ref|XP_523820.2| PREDICTED: similar to heterochromatin protein 1 beta [Pan troglodytes]
176.0 [0..30] [206..191]
gi|109488886 - gi|109488886|ref|XP_340886.3| PREDICTED: similar to Chromobox protein homolog 1 (Heterochromatin pro...
172.0 [0..30] [206..591]
gi|76645259 - gi|76645259|ref|XP_873631.1| PREDICTED: similar to Chromobox protein homolog 1 (Heterochromatin prot...
169.0 [0..30] [206..127]
gi|73976140 - gi|73976140|ref|XP_539136.2| PREDICTED: similar to chromobox homolog 3 isoform 1 [Canis familiaris]
169.0 [0..3] [206..9]
gi|209945056, gi... - gi|63146373|gb|AAY34032.1| heterochromatin protein 1A [Drosophila simulans], gi|209945056|gb|ACI9675...
167.0 [0..1] [206..1]
HP1_DROVI - Heterochromatin protein 1 OS=Drosophila virilis GN=HP1A PE=3 SV=1
162.0 [0..1] [206..1]
gi|83699408, gi|... - gi|83699408|ref|NP_031650.2| chromobox homolog 3 (Drosophila HP1 gamma) [Mus musculus], gi|80474659|...
162.0 [0..3] [206..9]
gi|58568516 - gi|58568516|gb|AAW78991.1| GekBS145P [Gekko japonicus]
161.0 [0..16] [206..22]

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Predicted Domain #1
Region A:
Residues: [1-77]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKIDNPES SAKVSDAEEE EEEYAVEKII DRRVRKGKVE YYLKWKGYPE TENTWEPENN  60
   61 LDCQDLIQQY EASRKDE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.221849
Match: 1knaA
Description: Heterochromatin protein 1, HP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription repressor activity 4.08500855631983 bayes_pls_golite062009
transcription regulator activity 3.64390820819794 bayes_pls_golite062009
methylated histone residue binding 3.42338304360938 bayes_pls_golite062009
chromatin binding 3.1924157640698 bayes_pls_golite062009
binding 3.06758476214113 bayes_pls_golite062009
protein binding 2.66728689880621 bayes_pls_golite062009
nucleic acid binding 2.19167058827256 bayes_pls_golite062009
DNA binding 2.05514577638135 bayes_pls_golite062009
histone binding 2.00388175060339 bayes_pls_golite062009
transcription activator activity 1.46529895769882 bayes_pls_golite062009
sequence-specific DNA binding 1.10020047862576 bayes_pls_golite062009
DNA-dependent ATPase activity 0.998957812785999 bayes_pls_golite062009
general transcriptional repressor activity 0.75184432495983 bayes_pls_golite062009
DNA helicase activity 0.726970683178132 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.494788451379878 bayes_pls_golite062009
transcription corepressor activity 0.294457188332415 bayes_pls_golite062009
catalytic activity 0.14067200158938 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [78-206]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKSAASKKDR PSSSAKAKET QGRASSSTST ASKRKSEEPT APSGNKSKRT TDAEQDTIPV  60
   61 SGSTGFDRGL EAEKILGASD NNGRLTFLIQ FKGVDQAEMV PSSVANEKIP RMVIHFYEER 120
  121 LSWYSDNED

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.045757
Match: 2fmmA
Description: No description for 2fmmA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle