YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7297069, gi\|2...
Organism:	Drosophila melanogaster
Length:	246 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7297069, gi|2....

Description	E-value	Query Range	Subject Range
FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima GN=fabG PE=3 SV=1 FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / D...	278.0	[0..3]	[244..2]
gi\|146296617, gi... - gi\|82501013\|ref\|ZP_00886394.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Caldicellulosiruptor sacc...	278.0	[0..1]	[244..1]
gi\|53688164 - gi\|53688164\|ref\|ZP_00110036.2\| COG1028: Dehydrogenases with different specificities (related to shor...	272.0	[0..2]	[244..107]
gi\|18310052, gi\|... - gi\|18310052\|ref\|NP_561986.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens st...	272.0	[0..4]	[244..2]
gi\|255313843 - gi\|255313843\|ref\|ZP_05355426.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255516524 - gi\|255516524\|ref\|ZP_05384200.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255649624 - gi\|255649624\|ref\|ZP_05396526.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|254974717 - gi\|254974717\|ref\|ZP_05271189.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255092105 - gi\|255092105\|ref\|ZP_05321583.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile CI... gi\|90575404, gi\|... - gi\|90575404\|ref\|ZP_01231888.1\| hypothetical protein CdifQ_02001165 [Clostridium difficile QCD-32g58]...	268.0	[0..1]	[244..1]
gi\|115250215, gi... - gi\|126698778\|ref\|YP_001087675.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile 6... gi\|255306086 - gi\|255306086\|ref\|ZP_05350258.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile AT... gi\|255100197 - gi\|255100197\|ref\|ZP_05329174.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC...	268.0	[0..1]	[244..1]
gi\|91184216, gi\|... - gi\|91217712\|ref\|ZP_01254669.1\| putative 3-oxoacyl-[acyl-carrier protein] reductase [Psychroflexus to...	268.0	[0..1]	[244..8]
gi\|168210762, gi... - gi\|170711222\|gb\|EDT23404.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens B st... gi\|110675446, gi... - gi\|110800799\|ref\|YP_695772.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens A... gi\|170660709, gi... - gi\|170660709\|gb\|EDT13392.1\| 3-oxoacyl- reductase [Clostridium perfringens E str. JGS1987], gi\|168207...	268.0	[0..4]	[244..2]
gi\|75908644, gi\|... - gi\|75908644\|ref\|YP_322940.1\| Short-chain dehydrogenase/reductase SDR [Anabaena variabilis ATCC 29413...	267.0	[0..2]	[243..37]
gi\|110803752, gi... - gi\|110803752\|ref\|YP_698460.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens S...	267.0	[0..4]	[244..2]

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Predicted Domain #1

Region A:
Residues: [1-246]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERWQNKLAV VTGASGGIGA ACARAMIGAG LRVVGLARRE AKLKELRESL PRELQANFIP  60
   61 RRCDVSKEDQ VQSSFDWIER ELEGADVLLN NAGITRETEL VTPSNTQKLK EVIDTNVMGV 120
  121 IWCTREAFNN MKRRGGEGHV LIINSIAGHQ VLNFIDVLPS FNIYPATKFA ITAITETYRQ 180
  181 EFQLHSNKIR VTGICPGAVN TNIFPEEIHF YVKDMARLEP ANIADAVMYA LRTPPHVQVS 240
  241 IITIMY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.69897
Match:	1xg5A
Description:	Structure of human putative dehydrogenase MGC4172 in complex with NADP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural molecule activity	2.31813292180084	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
fatty acid synthase activity	1.23679054027553	bayes_pls_golite062009
binding	0.982999356179965	bayes_pls_golite062009
oxidoreductase activity	0.9367410227151	bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity	0.604742541607263	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	0.54910246066113	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.418775403210681	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.32207755075663	bayes_pls_golite062009
DNA binding	0.302492036575815	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.196071455245233	bayes_pls_golite062009
transcription regulator activity	0.177044638410302	bayes_pls_golite062009
nucleic acid binding	0.100470710829263	bayes_pls_golite062009
transporter activity	0.0589212193613019	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: