YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|153196513, gi...
Organism:	Listeria monocytogenes 10403S
Length:	331 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|153196513, gi....

Description	E-value	Query Range	Subject Range
gi\|47096648, gi\|... - gi\|47096648\|ref\|ZP_00234235.1\| oxidoreductase, aldo/keto reductase family [Listeria monocytogenes st... gi\|254912564, gi... - gi\|254912564\|ref\|ZP_05262576.1\| hypothetical protein LmonJ2_07186 [Listeria monocytogenes J2818], gi... gi\|126943781, gi... - gi\|254899297\|ref\|ZP_05259221.1\| hypothetical protein LmonJ_05774 [Listeria monocytogenes J0161], gi\|... gi\|153180048, gi... - gi\|254936890\|ref\|ZP_05268587.1\| hypothetical protein LmonF6_07181 [Listeria monocytogenes F6900], gi...	361.0	[0..1]	[331..1]
gi\|25316285, gi\|... - pir\|\|AG1696 oxidoreductase homolog lin2113 [imported] - Listeria innocua (strain Clip11262), gi\|1641... gi\|16801179 - gi\|16801179\|ref\|NP_471447.1\| hypothetical protein lin2113 [Listeria innocua Clip11262]	361.0	[0..1]	[331..1]
gi\|226224603, gi... - gi\|226224603\|ref\|YP_002758710.1\| oxidoreductase [Listeria monocytogenes Clip81459], gi\|225877065\|emb... gi\|254877882 - gi\|254877882\|ref\|ZP_05250592.1\| oxidoreductase [Listeria monocytogenes FSL J2-071] gi\|254854362 - gi\|254854362\|ref\|ZP_05243710.1\| oxidoreductase [Listeria monocytogenes FSL R2-503] gi\|254825505 - gi\|254825505\|ref\|ZP_05230506.1\| oxidoreductase [Listeria monocytogenes FSL J1-194] gi\|133726722, gi... - gi\|153167851\|ref\|ZP_01927936.1\| hypothetical protein LMHG_01288 [Listeria monocytogenes FSL N1-017],... gi\|46908233, gi\|... - gi\|46908233\|ref\|YP_014622.1\| aldo/keto reductase family oxidoreductase [Listeria monocytogenes str. ...	360.0	[0..1]	[331..1]
gi\|33596263 - gi\|33596263\|ref\|NP_883906.1\| putative oxidoreductase [Bordetella parapertussis 12822] gi\|33573266 - gi\|33573266\|emb\|CAE36928.1\| putative oxidoreductase [Bordetella parapertussis]	360.0	[0..1]	[325..1]
gi\|33602077, gi\|... - gi\|33602077\|ref\|NP_889637.1\| putative oxidoreductase [Bordetella bronchiseptica RB50], gi\|33576515\|e...	360.0	[0..1]	[325..1]
gi\|33592063, gi\|... - gi\|33592063\|ref\|NP_879707.1\| putative oxidoreductase [Bordetella pertussis Tohama I], gi\|33571707\|em...	358.0	[0..1]	[325..1]
gi\|78062171, gi\|... - gi\|78062171\|ref\|YP_372079.1\| aldo/keto reductase [Burkholderia sp. 383], gi\|77970056\|gb\|ABB11435.1\| ...	354.0	[0..1]	[325..1]
gi\|91779252, gi\|... - gi\|91779252\|ref\|YP_554460.1\| putative aldo/keto reductase [Burkholderia xenovorans LB400], gi\|916919...	352.0	[0..1]	[325..1]
gi\|32141123, gi\|... - gi\|32141123\|ref\|NP_733514.1\| aldo/keto reductase [Streptomyces coelicolor A3(2)], gi\|24413737\|emb\|CA...	352.0	[0..1]	[326..1]
gi\|68227685, gi\|... - gi\|68227685\|ref\|ZP_00566891.1\| Aldo/keto reductase [Frankia sp. EAN1pec], gi\|68204973\|gb\|EAN19139.1\|...	349.0	[0..2]	[325..74]

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Predicted Domain #1

Region A:
Residues: [1-331]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYVKFGNTG MDVSKICLGT MGFGDKDKWI HKWVLDEANS RPIIKKALDL GINFFDTANI  60
   61 YSYGESEKIV GRALKDYANR DDIVLATKVQ QTMRPDRPNS GGLSRKTILS EIDHSLKRLE 120
  121 TDYVDLYIIH RFDENTPIEE TMEALHDVVK SGKARYIGAS AMYAWQFQKA QRVAERNGWT 180
  181 KFVSMQNHYN MIYREEEREM IPFCRDEKIA ITPYSPLASG RLTRDLNETT DRSETDPVQK 240
  241 SKYDDMMNAD KGIIERVAEL AETHQVSRDK IALAWLLNKD EITSPIIGAQ KESHLESAVE 300
  301 ALNIKLTTSE VNYLEELYIP HPVVGALPTT K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	80.522879
Match:	1pyfA
Description:	Structure of NADPH-dependent family 11 aldo-keto reductase AKR11A(apo)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
potassium channel activity	7.51963276589303	bayes_pls_golite062009
voltage-gated potassium channel activity	7.40239094355354	bayes_pls_golite062009
voltage-gated cation channel activity	6.67507110634301	bayes_pls_golite062009
metal ion transmembrane transporter activity	6.588881463055	bayes_pls_golite062009
voltage-gated ion channel activity	6.52286930358188	bayes_pls_golite062009
voltage-gated channel activity	6.50716590143831	bayes_pls_golite062009
cation channel activity	5.72172645555113	bayes_pls_golite062009
ion channel activity	5.15119282480682	bayes_pls_golite062009
channel activity	5.07214658557001	bayes_pls_golite062009
passive transmembrane transporter activity	5.07214658557001	bayes_pls_golite062009
substrate-specific channel activity	5.02503292701043	bayes_pls_golite062009
gated channel activity	4.92848832197692	bayes_pls_golite062009
pyridoxine 4-dehydrogenase activity	3.25535446462297	bayes_pls_golite062009
ion transmembrane transporter activity	2.63772951680109	bayes_pls_golite062009
cation transmembrane transporter activity	2.58068601897668	bayes_pls_golite062009
aldo-keto reductase activity	2.57303336304449	bayes_pls_golite062009
aryl-alcohol dehydrogenase activity	2.5168190536972	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.46488926936937	bayes_pls_golite062009
alpha-keto ester reductase activity	2.31616201247794	bayes_pls_golite062009
alpha-keto amide reductase activity	2.31616201247794	bayes_pls_golite062009
steroid dehydrogenase activity	2.19555484888528	bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.87468990921314	bayes_pls_golite062009
catalytic activity	1.68179794468736	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.48881830724998	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.37056379693287	bayes_pls_golite062009
transporter activity	1.24767072239634	bayes_pls_golite062009
oxidoreductase activity	1.17915737521094	bayes_pls_golite062009
aldehyde reductase activity	1.16639404121425	bayes_pls_golite062009
binding	1.15657176144267	bayes_pls_golite062009
transmembrane transporter activity	1.03420335553507	bayes_pls_golite062009
potassium channel regulator activity	1.03017249802223	bayes_pls_golite062009
substrate-specific transporter activity	0.783004917746429	bayes_pls_golite062009
protein binding	0.220529867719707	bayes_pls_golite062009
3-alpha-hydroxysteroid dehydrogenase (B-specific) activity	0.207008954325429	bayes_pls_golite062009
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	0.207008954325429	bayes_pls_golite062009
	0.139676323362391	bayes_pls_golite062009
channel regulator activity	0.12154513851913	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: