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View Structure Prediction Details

Protein: gi|114658395
Organism: Pan troglodytes
Length: 362 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|114658395.

Description E-value Query
Range		 Subject
Range
MO4L1_MOUSE - Mortality factor 4-like protein 1 OS=Mus musculus GN=Morf4l1 PE=1 SV=2
 0.0 [1..362] [1..362]
gi|109082084 - gi|109082084|ref|XP_001108618.1| PREDICTED: similar to Mortality factor 4-like protein 1 (MORF-relat...
 0.0 [1..362] [1..362]
gi|114658399 - gi|114658399|ref|XP_001152223.1| PREDICTED: MORF-related gene 15 isoform 4 [Pan troglodytes]
 0.0 [1..362] [1..361]
gi|73951711 - gi|73951711|ref|XP_852758.1| PREDICTED: similar to Mortality factor 4-like protein 1 (MORF-related g...
 0.0 [12..362] [36..385]
MG15_MOUSE - (P60762) Transcription factor-like protein MRG15 (MORF-related gene 15 protein) (Mortality factor 4-...
gi|114658397 - gi|114658397|ref|XP_001152351.1| PREDICTED: MORF-related gene 15 isoform 6 [Pan troglodytes]
gi|123984365, gi... - gi|168279109|dbj|BAG11434.1| mortality factor 4-like protein 1 [synthetic construct], gi|123998323|g...
gi|4454704, gi|1... - gi|8895208|gb|AAF80854.1|AF167173_1 MSL3-1 protein [Homo sapiens], gi|6841360|gb|AAF29033.1|AF161546...
gi|54035370 - gb|AAH84008.1| Unknown (protein for MGC:98166) [Xenopus laevis]
gi|109082086 - gi|109082086|ref|XP_001108662.1| PREDICTED: similar to mortality factor 4 like 1 isoform b isoform 3...
 0.0 [1..362] [1..323]
MO4L1_PONAB - Mortality factor 4-like protein 1 OS=Pongo abelii GN=MORF4L1 PE=2 SV=1
MO4L1_PONPY - Mortality factor 4-like protein 1 - Pongo pygmaeus (Orangutan)
 0.0 [1..362] [1..323]
gi|67968852 - gi|67968852|dbj|BAE00783.1| unnamed protein product [Macaca fascicularis]
 0.0 [1..362] [1..323]
MO4L1_RAT - Mortality factor 4-like protein 1 OS=Rattus norvegicus GN=Morf4l1 PE=2 SV=1
 0.0 [1..362] [1..323]

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Predicted Domain #1
Region A:
Residues: [1-189] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPKQDPKPK FQEGERVLCF HGPLLYEAKC VKVAIKDKQV KYFIHYSGWN KKSAVRPRRS  60
   61 EKSLKTHEDI VALFPVPEGA PSVHHPLLTS SWDEWVPESR VLKYVDTNLQ KQRELQKANQ 120
  121 EQYAEGKMRG AAPGKKTSGL QQKNVEVKTK KNKQKTPGNG DGGSTSETPQ PPRKKRARVD 180
  181 PTVENEETF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.09691
Match: 2efiA
Description: No description for 2efiA was found.

Predicted functions:

Term Confidence Notes
transcription repressor activity 4.08500855631983 bayes_pls_golite062009
chromatin binding 3.84065302930105 bayes_pls_golite062009
transcription regulator activity 3.64390820819794 bayes_pls_golite062009
methylated histone residue binding 3.42338304360938 bayes_pls_golite062009
binding 3.06758476214113 bayes_pls_golite062009
protein binding 2.66728689880621 bayes_pls_golite062009
nucleic acid binding 2.19167058827256 bayes_pls_golite062009
DNA binding 2.05514577638135 bayes_pls_golite062009
histone binding 2.00388175060339 bayes_pls_golite062009
satellite DNA binding 1.4681464542396 bayes_pls_golite062009
transcription activator activity 1.46529895769882 bayes_pls_golite062009
sequence-specific DNA binding 1.10020047862576 bayes_pls_golite062009
DNA-dependent ATPase activity 0.998957812785999 bayes_pls_golite062009
general transcriptional repressor activity 0.75184432495983 bayes_pls_golite062009
DNA helicase activity 0.726970683178132 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.494788451379878 bayes_pls_golite062009
transcription corepressor activity 0.294457188332415 bayes_pls_golite062009
catalytic activity 0.14067200158938 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [190-362] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRVEVKVKI PEELKPWLVD DWDLITRQKQ LFYLPAKKNV DSILEDYANY KKSRGNTDNK  60
   61 EYAVNEVVAG IKEYFNVMLG TQLLYKFERP QYAEILADHP DAPMSQVYGA PHLLRLFVRI 120
  121 GAMLAYTPLD EKSLALLLNY LHDFLKYLAK NSATLFSASD YEVAPPEYHR KAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.69897
Match: 2aqlA
Description: Crystal Structure of the MRG15 MRG domain
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle