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View Structure Prediction Details

Protein: gi|26344600, gi|...
Organism: Mus musculus
Length: 149 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|26344600, gi|....

Description E-value Query
Range
Subject
Range
RNAS1_MUSSA - Ribonuclease pancreatic OS=Mus saxicola GN=Rnase1 PE=2 SV=1
255.0 [0..1] [149..1]
RNS1A_RATEX - Ribonuclease pancreatic alpha-type OS=Rattus exulans PE=3 SV=1
251.0 [0..1] [149..1]
gi|18376502 - gi|18376502|emb|CAC86435.1| pancreatic ribonuclease alpha [Berylmys bowersi]
249.0 [0..1] [148..1]
RNAS1_URARU - Ribonuclease pancreatic OS=Uranomys ruddi GN=RNASE1 PE=2 SV=1
248.0 [0..1] [149..1]
RNAS1_MUSPA - Ribonuclease pancreatic OS=Mus pahari GN=Rnase1 PE=2 SV=1
246.0 [0..1] [149..1]
RNAS1_NIVCR - Ribonuclease pancreatic OS=Niviventer cremoriventer GN=RNASE1 PE=2 SV=1
245.0 [0..1] [149..1]
RNS1A_RATFU - Ribonuclease pancreatic alpha-type OS=Rattus fuscipes PE=3 SV=1
243.0 [0..1] [149..1]
RNAS1_ABRJE - Ribonuclease pancreatic OS=Abrothrix jelskii GN=RNASE1 PE=2 SV=1
243.0 [0..1] [149..1]
RNAS1_LEOED, RNP... - (Q9WUS3) Ribonuclease pancreatic precursor (EC 3.1.27.5) (RNase 1) (RNase A), (Q9WUS3) Ribonuclease ...
RNAS1_LEOED - Ribonuclease pancreatic OS=Leopoldamys edwardsi GN=RNASE1 PE=2 SV=1
240.0 [0..1] [148..1]

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Predicted Domain #1
Region A:
Residues: [1-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLEKSLILF PLFVLLLGWV QPSLGRESAA QKFQRQHMDP DGSSINSPTY CNQMMKRRDM  60
   61 TNGSCKPVNT FVHEPLADVQ AVCSQENVTC KNRKSNCYKS SSALHITDCH LKGNSKYPNC 120
  121 DYKTTQYQKH IIVACEGNPY VPVHFDATV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.0
Match: 1c0bA
Description: Ribonuclease A (also ribonuclease B, S)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease activity 10.4228433759815 bayes_pls_golite062009
copper ion binding 7.83873950118271 bayes_pls_golite062009
glycosaminoglycan binding 5.76187095683544 bayes_pls_golite062009
heparin binding 5.47129826629317 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 5.17394108203326 bayes_pls_golite062009
polysaccharide binding 5.05032546822599 bayes_pls_golite062009
actin binding 4.92941980452441 bayes_pls_golite062009
cytoskeletal protein binding 4.36902055736911 bayes_pls_golite062009
receptor binding 3.75411703515817 bayes_pls_golite062009
pattern binding 3.51086739633778 bayes_pls_golite062009
nuclease activity 3.07697924678131 bayes_pls_golite062009
hydrolase activity 2.85517340051306 bayes_pls_golite062009
carbohydrate binding 2.53927247892334 bayes_pls_golite062009
binding 2.456168052491 bayes_pls_golite062009
RNA binding 2.36041337585723 bayes_pls_golite062009
protein binding 2.18342402068792 bayes_pls_golite062009
nucleic acid binding 2.03519718891127 bayes_pls_golite062009
DNA binding 1.74627208866206 bayes_pls_golite062009
catalytic activity 1.25983854650131 bayes_pls_golite062009
transition metal ion binding 1.13983199214716 bayes_pls_golite062009
endonuclease activity 0.716350502288269 bayes_pls_golite062009
ion binding 0.595243569666936 bayes_pls_golite062009
cation binding 0.579280414941568 bayes_pls_golite062009
metal ion binding 0.579280414941568 bayes_pls_golite062009
endoribonuclease activity 0.390109603204743 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle