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View Structure Prediction Details

Protein: PGRC1_MOUSE
Organism: Mus musculus
Length: 195 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PGRC1_MOUSE.

Description E-value Query
Range		 Subject
Range
PGRC1_PONPY - Membrane-associated progesterone receptor component 1 - Pongo pygmaeus (Orangutan)
PGRC1_PONAB - Membrane-associated progesterone receptor component 1 OS=Pongo abelii GN=PGRMC1 PE=2 SV=3
 204.0 [0..1] [195..1]
gi|74212322 - gi|74212322|dbj|BAE40314.1| unnamed protein product [Mus musculus]
 203.0 [0..1] [195..1]
PGRMC1 - progesterone receptor membrane component 1
HGNC:16090|MIM:3... - receptor membrane component 1
gi|123981742, gi... - gi|123996565|gb|ABM85884.1| progesterone receptor membrane component 1 [synthetic construct], gi|123...
 203.0 [0..1] [195..1]
gi|57112339 - gi|57112339|ref|XP_538151.1| PREDICTED: similar to progesterone receptor membrane component [Canis f...
 198.0 [0..1] [195..1]
gi|7513461 - pir||JC5260 progesterone membrane binding protein - pig
PGRC1_PIG - Membrane-associated progesterone receptor component 1 OS=Sus scrofa GN=PGRMC1 PE=1 SV=3
 198.0 [0..1] [195..1]
PGRC1_BOVIN - Membrane-associated progesterone receptor component 1 OS=Bos taurus GN=PGRMC1 PE=2 SV=3
 197.0 [0..1] [195..1]
gi|109132048 - gi|109132048|ref|XP_001100639.1| PREDICTED: similar to progesterone receptor membrane component 1 [M...
 197.0 [0..1] [195..1]
PGRC2_RAT - Membrane-associated progesterone receptor component 2 OS=Rattus norvegicus GN=Pgrmc2 PE=1 SV=1
 192.0 [0..4] [192..30]

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Predicted Domain #1
Region A:
Residues: [1-195] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAEDVVATG ADPSELEGGG LLHEIFTSPL NLLLLGLCIF LLYKIVRGDQ PGASGDNDDD  60
   61 EPPPLPRLKR RDFTPAELRR FDGVQDPRIL MAINGKVFDV TKGRKFYGPE GPYGVFAGRD 120
  121 ASRGLATFCL DKEALKDEYD DLSDLTPAQQ ETLSDWDSQF TFKYHHVGKL LKEGEEPTVY 180
  181 SDDEEPKDET ARKNE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.0
Match: 1j03A
Description: Solution structure of a putative steroid-binding protein from Arabidopsis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.61930799072963 bayes_pls_golite062009
transporter activity 0.920087041947819 bayes_pls_golite062009
transmembrane transporter activity 0.739503099682459 bayes_pls_golite062009
substrate-specific transporter activity 0.535501995010142 bayes_pls_golite062009
receptor activity 0.452968145702868 bayes_pls_golite062009
protein binding 0.391553538500747 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.314610777889032 bayes_pls_golite062009
ion transmembrane transporter activity 0.0578908750434612 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle