YRC Public Data Repository - Protein Structure Prediction

Protein:	YAD7_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	527 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YAD7_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|46113357, gi\|... - gi\|68054113\|ref\|ZP_00538277.1\| 23S rRNA methyltransferase/RumA [Exiguobacterium sibiricum 255-15], g...	305.0	[0..106]	[527..2]
Y1863_LISIN - Uncharacterized RNA methyltransferase lin1863 OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=... Y1863_LISIN, YI6... - (Q92AQ7) Hypothetical RNA methyltransferase lin1863 (EC 2.1.1.-), Uncharacterized RNA methyltransfer...	304.0	[0..103]	[525..1]
gi\|51893956, gi\|... - gi\|51893956\|ref\|YP_076647.1\| RNA methyltransferase [Symbiobacterium thermophilum IAM 14863], gi\|5185...	304.0	[0..101]	[524..2]
gi\|226224354, gi... - gi\|226224354\|ref\|YP_002758461.1\| hypothetical RNA methyltransferase [Listeria monocytogenes Clip8145... gi\|254992256 - gi\|254992256\|ref\|ZP_05274446.1\| hypothetical RNA methyltransferase [Listeria monocytogenes FSL J2-06... Y1776_LISMF - Uncharacterized RNA methyltransferase LMOf2365_1776 OS=Listeria monocytogenes serotype 4b (strain F2...	303.0	[0..103]	[523..1]
gi\|47095677, gi\|... - gi\|47095677\|ref\|ZP_00233284.1\| RNA methyltransferase, TrmA family [Listeria monocytogenes str. 1/2a ... gi\|255028262 - gi\|255028262\|ref\|ZP_05300213.1\| hypothetical protein LmonL_01654 [Listeria monocytogenes LO28] YH51_LISMO, Y175... - (Q8Y6D6) Hypothetical RNA methyltransferase lmo1751 (EC 2.1.1.-), Uncharacterized RNA methyltransfer... gi\|126941860, gi... - gi\|254900744\|ref\|ZP_05260668.1\| hypothetical protein LmonJ_13049 [Listeria monocytogenes J0161], gi\|... gi\|224503324 - gi\|224503324\|ref\|ZP_03671631.1\| hypothetical protein LmonFR_12550 [Listeria monocytogenes FSL R2-561... Y1751_LISMO - Uncharacterized RNA methyltransferase lmo1751 OS=Listeria monocytogenes serovar 1/2a (strain ATCC BA... gi\|127765381, gi... - gi\|254913771\|ref\|ZP_05263783.1\| hypothetical protein LmonJ2_13279 [Listeria monocytogenes J2818], gi... gi\|133732615, gi... - gi\|254938158\|ref\|ZP_05269855.1\| hypothetical protein LmonF6_13559 [Listeria monocytogenes F6900], gi...	302.0	[0..103]	[523..1]
YEFA_BACSU, RLMC... - Uncharacterized RNA methyltransferase yefA OS=Bacillus subtilis GN=yefA PE=3 SV=1, 23S rRNA (uracil-... gi\|221312833 - gi\|221312833\|ref\|ZP_03594638.1\| hypothetical protein BsubsN3_03754 [Bacillus subtilis subsp. subtili... RLMCD_BACSU - 23S rRNA (uracil-C(5))-methyltransferase RlmCD OS=Bacillus subtilis (strain 168) GN=rlmCD PE=1 SV=1 gi\|221317757 - gi\|221317757\|ref\|ZP_03599051.1\| hypothetical protein BsubsJ_03708 [Bacillus subtilis subsp. subtilis... gi\|221322036 - gi\|221322036\|ref\|ZP_03603330.1\| hypothetical protein BsubsS_03794 [Bacillus subtilis subsp. subtilis...	302.0	[0..105]	[525..4]
Y687_BACHD - Uncharacterized RNA methyltransferase BH0687 OS=Bacillus halodurans GN=BH0687 PE=3 SV=1 Y687_BACHD - Uncharacterized RNA methyltransferase BH0687 OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197...	301.0	[0..103]	[525..3]
gi\|47092904, gi\|... - gi\|47092904\|ref\|ZP_00230686.1\| RNA methyltransferase, TrmA family [Listeria monocytogenes str. 4b H7... gi\|255521018 - gi\|255521018\|ref\|ZP_05388255.1\| hypothetical RNA methyltransferase [Listeria monocytogenes FSL J1-17...	301.0	[0..103]	[523..1]
gi\|52784541, gi\|... - gi\|52784541\|ref\|YP_090370.1\| YefA [Bacillus licheniformis ATCC 14580], gi\|52347043\|gb\|AAU39677.1\| Ye...	301.0	[0..102]	[525..1]
TRM2_YEAST - tRNA (uracil(54)-C(5))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN... TRM2 - tRNA methyltransferase, 5-methylates the uridine residue at position 54 of tRNAs and may also have a...	299.0	[0..25]	[524..46]

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Predicted Domain #1

Region A:
Residues: [1-102]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYPYCLKYLT NGLRSKQMIN FLCIQNILSA RTLKICRFRF LPTPSHPTHK MAQETRAISS  60
   61 ISEAANKRAR KLSKRRAKKP VEEGSSGHVL LLEIENLIEK PV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.39794
Match:	1neeA
Description:	Structure of archaeal translation factor aIF2beta from Methanobacterium thermoautrophicum
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [103-527]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LANVPFERFQ EIEVKISYLS SSGDGIGLVC NDQYAVVVPF TLPGDIVKAK LHFLADTYAL  60
   61 ADFLEVISPS EDRDDTLIKC PYFAKCGGCQ YQMLSYDKQL LQKKRVVEKA FQYYSKLDSS 120
  121 LLPAIKDTVG SPLQYNYRTK ITPHFDVPKG GTKGPLIIGF QEKGRRRVMD IEECPIATKT 180
  181 INEEYPKIIE DVQSRANTFK RGATILMRDS ATEDGKHCVI TDHKMIVREQ FGDLSFTFPA 240
  241 GAFFQNNNSI LEKFTSYVRE QLLNPFGRKE HQRPKYFVDA YCGSGLFSVA CSKGFLSVIG 300
  301 VEISADSVRY AEENAKRNNV SNATFIVGQA EKIFSSIETP PNETAMVIDP PRKGCDQSFL 360
  361 NQLLEYSPYR IVYISCNVHT QARDVGFLLS QEKGRSYKID EIRGFDLFPQ SHHVESILTL 420
  421 TKVVS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.39794
Match:	1uwvA
Description:	Crystal Structure of RumA, the iron-sulfur cluster containing E. coli 23S Ribosomal RNA 5-Methyluridine Methyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	4.15445027778357	bayes_pls_golite062009
rRNA methyltransferase activity	4.09362182773099	bayes_pls_golite062009
N-methyltransferase activity	4.07806017452628	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.07153733729662	bayes_pls_golite062009
protein methyltransferase activity	3.92746815303714	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.39429041855776	bayes_pls_golite062009
RNA methyltransferase activity	3.07428840534971	bayes_pls_golite062009
histone methyltransferase activity	2.99461585647365	bayes_pls_golite062009
tRNA methyltransferase activity	2.5931020126592	bayes_pls_golite062009
arginine N-methyltransferase activity	2.41876112831625	bayes_pls_golite062009
protein-arginine N-methyltransferase activity	2.41876112831625	bayes_pls_golite062009
transferase activity	2.22303238506686	bayes_pls_golite062009
DNA-methyltransferase activity	2.18991764495147	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	2.04350689362549	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	2.04350689362549	bayes_pls_golite062009
histone-arginine N-methyltransferase activity	2.04296107639729	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	2.04218282227834	bayes_pls_golite062009
tRNA (cytosine)-methyltransferase activity	1.88889414729709	bayes_pls_golite062009
tRNA (cytosine-5-)-methyltransferase activity	1.88889414729709	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	1.83964463328968	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	1.75675289134467	bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity	1.66871163498737	bayes_pls_golite062009
tRNA (adenine-N1-)-methyltransferase activity	1.29759910099835	bayes_pls_golite062009
tRNA (adenine)-methyltransferase activity	1.29759910099835	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific)	1.1103522853299	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	1.10713374933008	bayes_pls_golite062009
ligase activity	1.06979791212194	bayes_pls_golite062009
single-stranded DNA binding	0.97496043954059	bayes_pls_golite062009
structural constituent of ribosome	0.943661008731946	bayes_pls_golite062009
transcription regulator activity	0.914549843668268	bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity	0.89325812193225	bayes_pls_golite062009
DNA binding	0.86027591375666	bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity	0.703178429468566	bayes_pls_golite062009
ribonuclease activity	0.702449673647117	bayes_pls_golite062009
nucleic acid binding	0.616949327277483	bayes_pls_golite062009
structural molecule activity	0.596857566298868	bayes_pls_golite062009
aspartate-tRNA ligase activity	0.504302440847948	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	0.449277083957511	bayes_pls_golite062009
RNA binding	0.417524996559564	bayes_pls_golite062009
exoribonuclease activity	0.40223812695012	bayes_pls_golite062009
binding	0.383237930789959	bayes_pls_golite062009
sequence-specific DNA binding	0.32084431704638	bayes_pls_golite062009
transcription factor activity	0.298729064067577	bayes_pls_golite062009
O-methyltransferase activity	0.250946859465502	bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity	0.234572322347698	bayes_pls_golite062009
translation regulator activity	0.22908707234671	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	0.203168546434167	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.179682348023561	bayes_pls_golite062009
3'-5'-exoribonuclease activity	0.13299060447839	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: