| Protein: | MTHR1_SCHPO |
| Organism: | Schizosaccharomyces pombe 972h- |
| Length: | 603 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTHR1_SCHPO.
| Description | E-value | Query Range |
Subject Range |
|
|
872.0 | [0..1] | [595..1] |
|
|
872.0 | [0..1] | [597..1] |
|
|
867.0 | [0..1] | [597..1] |
|
|
865.0 | [0..1] | [587..1] |
|
|
851.0 | [0..1] | [597..1] |
|
|
849.0 | [0..2] | [590..18] |
|
|
848.0 | [0..2] | [596..67] |
|
|
848.0 | [0..2] | [596..67] |
|
|
847.0 | [0..1] | [602..1] |
|
Region A: Residues: [1-293] |
1 11 21 31 41 51
| | | | | |
1 MKISDKLLHP DWKEKVTYSY EFFPPKTSTG VQNLYNRIDR MKTWGRPMFV DVTWGAGGTS 60
61 SELTPGIVNV IQTDFEVDTC MHLTCTNMST EMIDAALKRA HETGCRNILA LRGDPVKDTD 120
121 WTEGESGFRY ASDLVRYIRT HYNDEFCIGV AGYPEGYSPD DDIDESIKHL KLKVDEGADF 180
181 IVTQMFYDVD NFIAWVDKVR AAGINIPIFP GIMPIQAWDS FIRRAKWSGV KIPQHFMDTL 240
241 VPVKDDDEGV RERGVELIVE MCRKLIASGI TRLHFYTMNL EKAVKMIIER LGL
|
| Detection Method: |  |
| Confidence: | 104.0 |
| Match: | 1v93A |
| Description: | 5,10-Methylenetetrahydrofolate Reductase from Thermus thermophilus HB8 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| methylenetetrahydrofolate reductase (NADPH) activity | 3.97406471031265 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-NH group of donors | 3.43788898294589 | bayes_pls_golite062009 |
| oxidoreductase activity | 3.26500423104107 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor | 2.35093189018748 | bayes_pls_golite062009 |
| catalytic activity | 2.15527229494088 | bayes_pls_golite062009 |
| 1-pyrroline-5-carboxylate dehydrogenase activity | 2.11575302268542 | bayes_pls_golite062009 |
| binding | 1.55766253746824 | bayes_pls_golite062009 |
| transcription regulator activity | 0.413628997019645 | bayes_pls_golite062009 |
| nucleic acid binding | 0.385543917258092 | bayes_pls_golite062009 |
| protein binding | 0.229798056306674 | bayes_pls_golite062009 |
| DNA binding | 0.214617895050106 | bayes_pls_golite062009 |
|
Region A: Residues: [294-452] |
1 11 21 31 41 51
| | | | | |
1 LDENLAPIVD TNNVELTNAS SQDRRINEGV RPIFWRTRNE SYVSRTDQWD ELPHGRWGDS 60
61 RSPAFGEFDA IRYGLRMSPK EITTSWGSPK SYSEIGDLFA RYCEKKISSL PWSDLPISDE 120
121 ADLIRDQLLS MNRNAFLTIN SQPALNGEKS SHPVFGWGP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [453-603] |
1 11 21 31 41 51
| | | | | |
1 PNGYVFQKPY VEFFVHPSLL NELKETVKKL NSVSYFVTNK NGDLDTNSQY EIPNAVTWGV 60
61 FPNREIIQPT IVESTSFLAW KDEAYSLGME WANAYSPDSI SRKLLVSMMK EWFLCVIVDN 120
121 DFQNGQSLFD VFNKMRSLKD IHPELYYANA S
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.807 | 0.078 | methylenetetrahydrofolate reductase (NADPH) activity | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
