YRC Public Data Repository - Protein Structure Prediction

Protein:	THRC_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	514 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for THRC_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|46442416, gi\|... - gi\|68470595\|ref\|XP_720543.1\| hypothetical protein CaO19.4233 [Candida albicans SC5314], gi\|68470332\|... orf19.11708, orf... - THR4 CGDID:CAL0000179 Assembly 19, Contig19-10202 (29952, 31484) CDS, translated using codon table 1...	374.0	[0..2]	[509..3]
gi\|85081402 - gi\|85081402\|ref\|XP_956711.1\| threonine synthase [Neurospora crassa OR74A] gi\|28917786, gi\|... - gi\|32404140\|ref\|XP_322683.1\| hypothetical protein [Neurospora crassa], gi\|28917786\|gb\|EAA27475.1\| th...	363.0	[0..6]	[512..22]
gi\|116200013, gi... - gi\|88179441\|gb\|EAQ86909.1\| threonine synthase [Chaetomium globosum CBS 148.51], gi\|116200013\|ref\|XP_...	363.0	[0..2]	[502..16]
THRC_ASHGO - Threonine synthase OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) GN=... THRC_ASHGO - Threonine synthase OS=Ashbya gossypii GN=THR4 PE=3 SV=1	359.0	[0..7]	[512..5]
gi\|49656839 - gi\|49656839\|emb\|CAG89555.1\| DEHA2F18986p [Debaryomyces hansenii] gi\|49656839, gi\|... - gi\|50425157\|ref\|XP_461170.1\| hypothetical protein DEHA0F20240g [Debaryomyces hansenii CBS767], gi\|49...	359.0	[0..1]	[512..1]
gi\|111064417 - gi\|111064417\|gb\|EAT85537.1\| hypothetical protein SNOG_06886 [Phaeosphaeria nodorum SN15]	358.0	[0..1]	[510..1]
gi\|50556742, gi\|... - gi\|50556742\|ref\|XP_505779.1\| YALI0F23221p [Yarrowia lipolytica], gi\|49651649\|emb\|CAG78590.1\| unnamed... gi\|49651649 - gi\|49651649\|emb\|CAG78590.1\| YALI0F23221p [Yarrowia lipolytica]	356.0	[0..7]	[513..4]
gi\|49641734, gi\|... - gi\|50305283\|ref\|XP_452601.1\| unnamed protein product [Kluyveromyces lactis], gi\|49641734\|emb\|CAH0145... gi\|49641734 - gi\|49641734\|emb\|CAH01452.1\| KLLA0C09020p [Kluyveromyces lactis]	355.0	[0..1]	[513..1]
gi\|49527937 - gi\|49527937\|emb\|CAG61588.1\| unnamed protein product [Candida glabrata] gi\|50292385, gi\|... - gi\|50292385\|ref\|XP_448625.1\| unnamed protein product [Candida glabrata], gi\|49527937\|emb\|CAG61588.1\|...	354.0	[0..1]	[512..1]
gi\|115399997, gi... - gi\|115399997\|ref\|XP_001215587.1\| threonine synthase [Aspergillus terreus NIH2624], gi\|114191253\|gb\|E...	353.0	[0..4]	[510..10]

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Predicted Domain #1

Region A:
Residues: [1-514]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSQVSYLST RGGSSNFSFE EAVLKGLAND GGLFIPSEIP QLPSGWIEAW KDKSFPEIAF  60
   61 EVMSLYIPRS EISADELKKL VDRSYSTFRH PETTPLKSLK NGLNVLELFH GPTFAFKDVA 120
  121 LQFLGNLFEF FLTRKNGNKP EDERDHLTVV GATSGDTGSA AIYGLRGKKD VSVFILFPNG 180
  181 RVSPIQEAQM TTVTDPNVHC ITVNGVFDDC QDLVKQIFGD VEFNKKHHIG AVNSINWARI 240
  241 LSQITYYLYS YLSVYKQGKA DDVRFIVPTG NFGDILAGYY AKRMGLPTKQ LVIATNENDI 300
  301 LNRFFKTGRY EKADSTQVSP SGPISAKETY SPAMDILVSS NFERYLWYLA LATEAPNHTP 360
  361 AEASEILSRW MNEFKRDGTV TVRPEVLEAA RRDFVSERVS NDETIDAIKK IYESDHYIID 420
  421 PHTAVGVETG LRCLEKTKDQ DITYICLSTA HPAKFDKAVN LALSSYSDYN FNTQVLPIEF 480
  481 DGLLDEERTC IFSGKPNIDI LKQIIEVTLS REKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	96.522879
Match:	1kl7A
Description:	Threonine synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
threonine synthase activity	3.59927532963055	bayes_pls_golite062009
carbon-oxygen lyase activity, acting on phosphates	2.61572425646119	bayes_pls_golite062009
catalytic activity	2.38994231321972	bayes_pls_golite062009
lyase activity	1.87743897464083	bayes_pls_golite062009
cysteine synthase activity	1.31641967296632	bayes_pls_golite062009
binding	1.19751827446411	bayes_pls_golite062009
tryptophan synthase activity	1.04832999357666	bayes_pls_golite062009
carbon-oxygen lyase activity	0.923824749425553	bayes_pls_golite062009
ammonia-lyase activity	0.476674617721478	bayes_pls_golite062009
L-threonine ammonia-lyase activity	0.37325071016009	bayes_pls_golite062009
protein binding	0.251404253093929	bayes_pls_golite062009
carbon-nitrogen lyase activity	0.249761226675912	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: