| Protein: | Dscam-PG |
| Organism: | Drosophila melanogaster |
| Length: | 2032 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PG.
| Description | E-value | Query Range |
Subject Range |
|
|
1553.0 | [0..3] | [2032..3] |
|
Region A: Residues: [1-232] |
1 11 21 31 41 51
| | | | | |
1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60
61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
121 NQFGSIISRD VHVRAVVAQY YEADVNKEHV IRGNSAVIKC LIPSFVADFV EVVSWHTDEE 180
181 ENYFPGAEYD GKYLVLPSGE LHIREVGPED GYKSYQCRTK HRLTGETRLS AT
|
| Detection Method: |  |
| Confidence: | 79.221849 |
| Match: | 2v5sA |
| Description: | No description for 2v5sA was found. |
|
Region A: Residues: [233-897] |
1 11 21 31 41 51
| | | | | |
1 KGRLVITEPV GSVGPKLTSG DDSRTVRIRQ EDSVTLLCPA QAYPVPVYRW YKFIEGTTRK 60
61 QAVVLNDRVK QVSGTLIIKD AVVEDSGKYL CVVNNSVGGE SVETVLTVTA PLSAKIDPPT 120
121 QTVDFGRPAV FTCQYTGNPI KTVSWMKDGK AIGHSEPVLR IESVKKEDKG MYQCFVRNDQ 180
181 ESAEASAELK LGGRFDPPVI RQAFQEETME PGPSVFLKCV AGGNPTPEIS WELDGKKIAN 240
241 NDRYQVGQYV TVNGDVVSYL NITSVHANDG GLYKCIAKSK VGVAEHSAKL NVYGLPYIRQ 300
301 MEKKAIVAGE TLIVTCPVAG YPIDSIVWER DNRALPINRK QKVFPNGTLI IENVERNSDQ 360
361 ATYTCVAKNQ EGYSARGSLE VQVMVPPSIA PFSFGDDPVN TGENAGVQCM VQKGDVPITI 420
421 KWTLNSRPII NGEEGITILK LSPKTSVLNI AAVEQDHRGV FKCIAENKAG SSFTTSELKV 480
481 NVPPRWILEP TDKAFAQGSD AKVECKADGF PKPQVTWKKA VGDTPGEYKD LKKSDNIRVE 540
541 EGTLHVDNIQ KTNEGYYLCE AINGIGSGLS AVIMISVQAP PEFTEKLRNQ TARRGEPAVL 600
601 QCEAKGEKPI GILWNMNNMR LDPKNDNRYT IREEILSTGV MSSLSIKRTE RSDSALFTCV 660
661 ATNAF
|
| Detection Method: | |
| Confidence: | 61.522879 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [898-1005] |
1 11 21 31 41 51
| | | | | |
1 GSDDASINMI VQEVPEMPYA LKVLDKSGRS VQLSWAQPYD GNSPLDRYII EFKRSRASWS 60
61 EIDRVIVPGH TTEAQVQKLS PATTYNIRIV AENAIGTSQS SEAVTIIT
|
| Detection Method: | |
| Confidence: | 36.69897 |
| Match: | 2nziA |
| Description: | No description for 2nziA was found. |
|
Region A: Residues: [1006-1117] |
1 11 21 31 41 51
| | | | | |
1 AEEAPSGKPQ NIKVEPVNQT TMRVTWKPPP RTEWNGEILG YYVGYKLSNT NSSYVFETIN 60
61 FITEEGKEHN LELQNLRVYT QYSVVIQAFN KIGAGPLSEE EKQFTAEGTP SQ
|
| Detection Method: | |
| Confidence: | 11.045757 |
| Match: | 2edxA |
| Description: | No description for 2edxA was found. |
|
Region A: Residues: [1118-1217] |
1 11 21 31 41 51
| | | | | |
1 PPSDTACTTL TSQTIRVGWV SPPLESANGV IKTYKVVYAP SDEWYDETKR HYKKTASSDT 60
61 VLHGLKKYTN YTMQVLATTA GGDGVRSVPI HCQTEPDVPE
|
| Detection Method: | |
| Confidence: | 8.0 |
| Match: | 2dlhA |
| Description: | No description for 2dlhA was found. |
|
Region A: Residues: [1218-1480] |
1 11 21 31 41 51
| | | | | |
1 APTDVKALVM GNAAILVSWR PPAQPNGIIT QYTVYSKAEG AETETKTQKV PHYQMSFEAT 60
61 ELEKNKPYEF WVTASTTIGE GQQSKSIVAM PSDQVPAKIA SFDDTFTATF KEDAKMPCLA 120
121 VGAPQPEITW KIKGVEFSAN DRMRVLPDGS LLIKSVNRQD AGDYSCHAEN SIAKDSITHK 180
181 LIVLAPPQSP HVTLSATTTD ALTVKLKPHE GDTAPLHGYT LHYKPEFGEW ETSEVSVDSQ 240
241 KHNIEGLLCG SRYQVYATGF NNI
|
| Detection Method: | |
| Confidence: | 13.39794 |
| Match: | 1tdqA |
| Description: | Structural basis for the interactions between tenascins and the C-type lectin domains from lecticans: evidence for a cross-linking role for tenascins |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.79244614134061 | bayes_pls_golite062009 |
| receptor activity | 3.73567137429359 | bayes_pls_golite062009 |
| cytokine binding | 3.58426984827737 | bayes_pls_golite062009 |
| signal transducer activity | 3.5100441341515 | bayes_pls_golite062009 |
| molecular transducer activity | 3.5100441341515 | bayes_pls_golite062009 |
| cytokine receptor activity | 3.25206686803048 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| growth factor binding | 2.4970104838834 | bayes_pls_golite062009 |
| receptor binding | 2.38673889309915 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| interleukin-2 binding | 1.67132604890013 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.56410665522466 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.53073516901486 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.53073516901486 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| mercury ion binding | 1.46191698606762 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.27192437373177 | bayes_pls_golite062009 |
| peptide hormone binding | 1.2420090521345 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| cytokine activity | 1.18680139050127 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| heparin binding | 1.15000556789505 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 1.1057194345531 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| protease binding | 0.942107032692451 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| growth hormone receptor activity | 0.840187286074179 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| cell surface binding | 0.630081242528945 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| collagen binding | 0.593745877718282 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| polysaccharide binding | 0.54737137289904 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.47107517390107 | bayes_pls_golite062009 |
| growth factor activity | 0.432629984792427 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| pattern binding | 0.31156427047296 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.301052531308189 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.115337814289139 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 0.0423783987133706 | bayes_pls_golite062009 |
| interleukin-11 binding | 0.0423783987133706 | bayes_pls_golite062009 |
|
Region A: Residues: [1481-1673] |
1 11 21 31 41 51
| | | | | |
1 GAGEASDILN TRTKGQKPKL PEKPRFIEVS SNSVSLHFKA WKDGGCPMSH FVVESKKRDQ 60
61 IEWNQISNNV KPDNNYVVLD LEPATWYNLR ITAHNSAGFT VAEYDFATLT VTGGTIAPLD 120
121 DGSGHGNVHT RIRLPAWMPE WLDLNFMVPL IATVVVVAVG ICVVCVALSR RRADDMRGGQ 180
181 KDVYYDVVYN QTM
|
| Detection Method: | |
| Confidence: | 11.0 |
| Match: | 1x5kA |
| Description: | The solution structure of the sixth fibronectin type III domain of human Neogenin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.79244614134061 | bayes_pls_golite062009 |
| receptor activity | 3.73567137429359 | bayes_pls_golite062009 |
| cytokine binding | 3.58426984827737 | bayes_pls_golite062009 |
| signal transducer activity | 3.5100441341515 | bayes_pls_golite062009 |
| molecular transducer activity | 3.5100441341515 | bayes_pls_golite062009 |
| cytokine receptor activity | 3.25206686803048 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| growth factor binding | 2.4970104838834 | bayes_pls_golite062009 |
| receptor binding | 2.38673889309915 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| interleukin-2 binding | 1.67132604890013 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.56410665522466 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.53073516901486 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.53073516901486 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| mercury ion binding | 1.46191698606762 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.27192437373177 | bayes_pls_golite062009 |
| peptide hormone binding | 1.2420090521345 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| cytokine activity | 1.18680139050127 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| heparin binding | 1.15000556789505 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 1.1057194345531 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| protease binding | 0.942107032692451 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| growth hormone receptor activity | 0.840187286074179 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| cell surface binding | 0.630081242528945 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| collagen binding | 0.593745877718282 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| polysaccharide binding | 0.54737137289904 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.47107517390107 | bayes_pls_golite062009 |
| growth factor activity | 0.432629984792427 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| pattern binding | 0.31156427047296 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.301052531308189 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.115337814289139 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 0.0423783987133706 | bayes_pls_golite062009 |
| interleukin-11 binding | 0.0423783987133706 | bayes_pls_golite062009 |
|
Region A: Residues: [1674-1791] |
1 11 21 31 41 51
| | | | | |
1 GPGATLDKRR PDLRDELGYI APPNRKLPPV PGSNYNTCDR IKRGRGGLRS NHSTWDPRRN 60
61 PNLYEELKAP PVPMHGNHYG HAHGNAECHY RHPGMEDEIC PYATFHLLGF REEMDPTK
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1792-1938] |
1 11 21 31 41 51
| | | | | |
1 AMNFQTFPHQ NGHAGPVPGH AGTMLPPGHP GHVHSRSGSQ SMPRANRYQR KNSQGGQSSI 60
61 YTPAPEYDDP ANCAEEDQYR RYTRVNSQGG SLYSGPGPEY DDPANCAPEE DQYGSQYGGP 120
121 YGQPYDHYGS RGSMGRRSIG SARNPGN
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1939-2032] |
1 11 21 31 41 51
| | | | | |
1 GSPEPPPPPP RNHDMSNSSF NDSKESNEIS EAECDRDHGP RGNYGAVKRS PQPKDQRTTE 60
61 EMRKLIERNE TGPKQLQLQQ ANGAGFTAYD TMAV
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
