| Protein: | Dscam-PAH |
| Organism: | Drosophila melanogaster |
| Length: | 2016 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PAH.
| Description | E-value | Query Range |
Subject Range |
|
|
1557.0 | [0..1] | [2016..1] |
|
Region A: Residues: [1-139] |
1 11 21 31 41 51
| | | | | |
1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60
61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
121 NQFGSIISRD VHVRAVVNQ
|
| Detection Method: |  |
| Confidence: | 78.522879 |
| Match: | 2v5sA |
| Description: | No description for 2v5sA was found. |
|
Region A: Residues: [140-817] |
1 11 21 31 41 51
| | | | | |
1 FYGADILMEY VIRGNAAVLK CSIPSFVADF VRVESWIDEE GTELRPSENY DGKYLVLPSG 60
61 ELHIREVGPE DGYKSYQCRT KHRLTGETRL SATKGRLVIT EPIGSKAPSV PTGVMVFQQQ 120
121 VPLLSTFAML CQAQAFPVPV FRWYKFIEGT TRKQAVVLND RVKQVSGTLI IKDAVVEDSG 180
181 KYLCVVNNSV GGESVETVLT VTAPLSAKID PPTQTVDFGR PAVFTCQYTG NPIKTVSWMK 240
241 DGKAIGHSEP VLRIESVKKE DKGMYQCFVR NDQESAEASA ELKLGGRFDP PVIRQAFQEE 300
301 TMEPGPSVFL KCVAGGNPTP EISWELDGKK IANNDRYQVG QYVTVNGDVV SYLNITSVHA 360
361 NDGGLYKCIA KSKVGVAEHS AKLNVYGLPY IRQMEKKAIV AGETLIVTCP VAGYPIDSIV 420
421 WERDNRALPI NRKQKVFPNG TLIIENVERN SDQATYTCVA KNQEGYSARG SLEVQVMVPP 480
481 KITPFTFGDE PTNVEDSVSV TCLISSGDLP IDIEWLFNDY GISSFSGMTV YRGGKRTSML 540
541 TIDNVHARHA GKYSCRARNH ASAVNFTTEL IVNVPPRWIL EPTDKAFAQG SDAKVECKAD 600
601 GFPKPQVTWK KAVGDTPGEY KDLKKSDNIR VEEGTLHVDN IQKTNEGYYL CEAINGIGSG 660
661 LSAVIMISVQ APPEFTEK
|
| Detection Method: | |
| Confidence: | 58.69897 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [818-1371] |
1 11 21 31 41 51
| | | | | |
1 LRNQTARRGE PAVLQCEAKG EKPIGILWNM NNMRLDPKND NRYTIREEIL STGVMSSLSI 60
61 KRTERSDSAL FTCVATNAFG SDDASINMIV QEVPEMPYAL KVLDKSGRSV QLSWAQPYDG 120
121 NSPLDRYIIE FKRSRASWSE IDRVIVPGHT TEAQVQKLSP ATTYNIRIVA ENAIGTSQSS 180
181 EAVTIITAEE APSGKPQNIK VEPVNQTTMR VTWKPPPRTE WNGEILGYYV GYKLSNTNSS 240
241 YVFETINFIT EEGKEHNLEL QNLRVYTQYS VVIQAFNKIG AGPLSEEEKQ FTAEGTPSQP 300
301 PSDTACTTLT SQTIRVGWVS PPLESANGVI KTYKVVYAPS DEWYDETKRH YKKTASSDTV 360
361 LHGLKKYTNY TMQVLATTAG GDGVRSVPIH CQTEPDVPEA PTDVKALVMG NAAILVSWRP 420
421 PAQPNGIITQ YTVYSKAEGA ETETKTQKVP HYQMSFEATE LEKNKPYEFW VTASTTIGEG 480
481 QQSKSIVAMP SDQVPAKIAS FDDTFTATFK EDAKMPCLAV GAPQPEITWK IKGVEFSAND 540
541 RMRVLPDGSL LIKS
|
| Detection Method: | |
| Confidence: | 30.30103 |
| Match: | 2v5yA |
| Description: | No description for 2v5yA was found. |
|
Region A: Residues: [1372-1598] |
1 11 21 31 41 51
| | | | | |
1 VNRQDAGDYS CHAENSIAKD SITHKLIVLA PPQSPHVTLS ATTTDALTVK LKPHEGDTAP 60
61 LHGYTLHYKP EFGEWETSEV SVDSQKHNIE GLLCGSRYQV YATGFNNIGA GEASDILNTR 120
121 TKGQKPKLPE KPRFIEVSSN SVSLHFKAWK DGGCPMSHFV VESKKRDQIE WNQISNNVKP 180
181 DNNYVVLDLE PATWYNLRIT AHNSAGFTVA EYDFATLTVT GGTIAPS
|
| Detection Method: | |
| Confidence: | 22.0 |
| Match: | 1fnhA |
| Description: | Fibronectin, different Fn3 modules |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| transmembrane receptor activity | 4.81256300373074 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| receptor activity | 4.66147271961356 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| cytokine binding | 4.43581512268554 | bayes_pls_golite062009 |
| cytokine receptor activity | 4.08668869714207 | bayes_pls_golite062009 |
| growth factor binding | 4.06808996928726 | bayes_pls_golite062009 |
| molecular transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| signal transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 3.5949595622742 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| receptor binding | 2.38673889309915 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| peptide hormone binding | 2.12033076929638 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| mercury ion binding | 1.85843060232985 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| interleukin-2 binding | 1.67132604890013 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.56410665522466 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.27192437373177 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| growth hormone receptor activity | 1.15929762138929 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| heparin binding | 1.15000556789505 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| cytokine activity | 1.09433218752101 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| peptide binding | 0.92031154055894 | bayes_pls_golite062009 |
| interleukin-6 binding | 0.888638861691021 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 0.888638861691021 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| collagen binding | 0.593745877718282 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.554350228628563 | bayes_pls_golite062009 |
| polysaccharide binding | 0.54737137289904 | bayes_pls_golite062009 |
| hormone binding | 0.49524185948356 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.47107517390107 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.46168925186147 | bayes_pls_golite062009 |
| pattern binding | 0.44460010885883 | bayes_pls_golite062009 |
| growth factor activity | 0.432629984792427 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| cell surface binding | 0.366415248711076 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.301052531308189 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protease binding | 0.12595904253108 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.115337814289139 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 0.0423783987133706 | bayes_pls_golite062009 |
| interleukin-11 binding | 0.0423783987133706 | bayes_pls_golite062009 |
|
Region A: Residues: [1599-1816] |
1 11 21 31 41 51
| | | | | |
1 RDLPELSAED TIRIILSNLN LVVPVVAALL VIIIAIIVIC ILRSKGNHHK DDVVYNQTMG 60
61 PGATLDKRRP DLRDELGYIA PPNRKLPPVP GSNYNTCDRI KRGRGGLRSN HSTWDPRRNP 120
121 NLYEELKAPP VPMHGNHYGH AHGNAECHYR HPGMEDEICP YATFHLLGFR EEMDPTKAMN 180
181 FQTFPHQNGH AGPVPGHAGT MLPPGHPGHV HSRSGSQS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1817-2016] |
1 11 21 31 41 51
| | | | | |
1 MPRANRYQRK NSQGGQSSIY TPAPEYDDPA NCAEEDQYRR YTRVNSQGGS LYSGPGPEYD 60
61 DPANCAPEED QYGSQYGGPY GQPYDHYGSR GSMGRRSIGS ARNPGNGSPE PPPPPPRNHD 120
121 MSNSSFNDSK ESNEISEAEC DRDHGPRGNY GAVKRSPQPK DQRTTEEMRK LIERNETGPK 180
181 QLQLQQANGA GFTAYDTMAV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
