| Protein: | Dscam-PR |
| Organism: | Drosophila melanogaster |
| Length: | 2013 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PR.
| Description | E-value | Query Range |
Subject Range |
|
|
1566.0 | [0..3] | [2013..3] |
|
Region A: Residues: [1-144] |
1 11 21 31 41 51
| | | | | |
1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60
61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
121 NQFGSIISRD VHVRAVVAQY YDTD
|
| Detection Method: |  |
| Confidence: | 80.69897 |
| Match: | 2v5sA |
| Description: | No description for 2v5sA was found. |
|
Region A: Residues: [145-252] |
1 11 21 31 41 51
| | | | | |
1 VNKAYVIRGN AAVLKCEIPS FVADFVSVVS WHTDQNEDFL PGSEYDGKYL VLPSGELHIR 60
61 EVGPEDGYKS YQCRTKHRLT GETRLSATKG RLVITEPVGS IGPRLTSG
|
| Detection Method: | |
| Confidence: | 10.09691 |
| Match: | 1igtB |
| Description: | Immunoglobulin heavy chain variable domain, VH; Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma; Immunoglobulin heavy chain gamma constant domain 2, CH2-gamma; Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 6.64811984458494 | bayes_pls_golite062009 |
| alpha-actinin binding | 5.77350124471385 | bayes_pls_golite062009 |
| actinin binding | 5.69539760434923 | bayes_pls_golite062009 |
| antigen binding | 5.59543448804521 | bayes_pls_golite062009 |
| structural constituent of muscle | 4.93896503565413 | bayes_pls_golite062009 |
| olfactory receptor activity | 4.21057154107121 | bayes_pls_golite062009 |
| receptor activity | 4.00123250685257 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.81769911097805 | bayes_pls_golite062009 |
| peptide antigen binding | 3.64034637674979 | bayes_pls_golite062009 |
| binding | 3.17641566810715 | bayes_pls_golite062009 |
| signal transducer activity | 3.10913345555941 | bayes_pls_golite062009 |
| molecular transducer activity | 3.10913345555941 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 2.83860944503193 | bayes_pls_golite062009 |
| IgG binding | 2.62006935586983 | bayes_pls_golite062009 |
| protein binding | 2.22855404705168 | bayes_pls_golite062009 |
| IgE binding | 1.73481096568834 | bayes_pls_golite062009 |
| IgE receptor activity | 1.73481096568834 | bayes_pls_golite062009 |
| receptor binding | 1.70260377709721 | bayes_pls_golite062009 |
| growth factor binding | 1.60826091835429 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.58610597245454 | bayes_pls_golite062009 |
| actin binding | 1.42681407553255 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 1.36789541796983 | bayes_pls_golite062009 |
| protein kinase activity | 1.36635494500222 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32330470851159 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 1.27793818082552 | bayes_pls_golite062009 |
| DNA binding | 1.19412627500732 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.17845072849922 | bayes_pls_golite062009 |
| transcription regulator activity | 1.16252234499274 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.02428106476324 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.02286631988334 | bayes_pls_golite062009 |
| kinase activity | 0.929878054374821 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.878595022643164 | bayes_pls_golite062009 |
| sugar binding | 0.851973726002024 | bayes_pls_golite062009 |
| immunoglobulin binding | 0.84834833214265 | bayes_pls_golite062009 |
| protein complex binding | 0.83543827718565 | bayes_pls_golite062009 |
| actin filament binding | 0.760856470721016 | bayes_pls_golite062009 |
| peptide binding | 0.729048089532569 | bayes_pls_golite062009 |
| coreceptor activity | 0.661209696849389 | bayes_pls_golite062009 |
| collagen binding | 0.635057461053063 | bayes_pls_golite062009 |
| cytokine binding | 0.631436442105379 | bayes_pls_golite062009 |
| titin binding | 0.599892148302011 | bayes_pls_golite062009 |
| integrin binding | 0.599569390248921 | bayes_pls_golite062009 |
| structural molecule activity | 0.567620977360967 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.564762108830441 | bayes_pls_golite062009 |
| transcription factor activity | 0.54549168007511 | bayes_pls_golite062009 |
| immunoglobulin receptor activity | 0.53605856667766 | bayes_pls_golite062009 |
| IgG receptor activity | 0.50231877534761 | bayes_pls_golite062009 |
| myosin heavy chain binding | 0.49788128784685 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.447829399094714 | bayes_pls_golite062009 |
| cytokine receptor activity | 0.34165331857492 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 0.318890055375093 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.28309679787333 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.0579247757286607 | bayes_pls_golite062009 |
|
Region A: Residues: [253-906] |
1 11 21 31 41 51
| | | | | |
1 DESRILRVYL AASATLLCPA QAYPVPFFRW YKFIEGTTRK QAVVLNDRVK QVSGTLIIKD 60
61 AVVEDSGKYL CVVNNSVGGE SVETVLTVTA PLSAKIDPPT QTVDFGRPAV FTCQYTGNPI 120
121 KTVSWMKDGK AIGHSEPVLR IESVKKEDKG MYQCFVRNDQ ESAEASAELK LGGRFDPPVI 180
181 RQAFQEETME PGPSVFLKCV AGGNPTPEIS WELDGKKIAN NDRYQVGQYV TVNGDVVSYL 240
241 NITSVHANDG GLYKCIAKSK VGVAEHSAKL NVYGLPYIRQ MEKKAIVAGE TLIVTCPVAG 300
301 YPIDSIVWER DNRALPINRK QKVFPNGTLI IENVERNSDQ ATYTCVAKNQ EGYSARGSLE 360
361 VQVMELPQVD QFHFNANGVN GGQAVRVMCM VSSGDLPIDI YWLKDGQPLL RSIYHKIDEY 420
421 TLILSLRQTT IGDSGNYTCV ASNAAGVASR WSILKVKVPP RWILEPTDKA FAQGSDAKVE 480
481 CKADGFPKPQ VTWKKAVGDT PGEYKDLKKS DNIRVEEGTL HVDNIQKTNE GYYLCEAING 540
541 IGSGLSAVIM ISVQAPPEFT EKLRNQTARR GEPAVLQCEA KGEKPIGILW NMNNMRLDPK 600
601 NDNRYTIREE ILSTGVMSSL SIKRTERSDS ALFTCVATNA FGSDDASINM IVQE
|
| Detection Method: | |
| Confidence: | 58.69897 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [907-1004] |
1 11 21 31 41 51
| | | | | |
1 VPEMPYALKV LDKSGRSVQL SWAQPYDGNS PLDRYIIEFK RSRASWSEID RVIVPGHTTE 60
61 AQVQKLSPAT TYNIRIVAEN AIGTSQSSEA VTIITAEE
|
| Detection Method: | |
| Confidence: | 37.30103 |
| Match: | 2nziA |
| Description: | No description for 2nziA was found. |
|
Region A: Residues: [1005-1109] |
1 11 21 31 41 51
| | | | | |
1 APSGKPQNIK VEPVNQTTMR VTWKPPPRTE WNGEILGYYV GYKLSNTNSS YVFETINFIT 60
61 EEGKEHNLEL QNLRVYTQYS VVIQAFNKIG AGPLSEEEKQ FTAEG
|
| Detection Method: | |
| Confidence: | 10.522879 |
| Match: | 2edxA |
| Description: | No description for 2edxA was found. |
|
Region A: Residues: [1110-1481] |
1 11 21 31 41 51
| | | | | |
1 TPSQPPSDTA CTTLTSQTIR VGWVSPPLES ANGVIKTYKV VYAPSDEWYD ETKRHYKKTA 60
61 SSDTVLHGLK KYTNYTMQVL ATTAGGDGVR SVPIHCQTEP DVPEAPTDVK ALVMGNAAIL 120
121 VSWRPPAQPN GIITQYTVYS KAEGAETETK TQKVPHYQMS FEATELEKNK PYEFWVTAST 180
181 TIGEGQQSKS IVAMPSDQVP AKIASFDDTF TATFKEDAKM PCLAVGAPQP EITWKIKGVE 240
241 FSANDRMRVL PDGSLLIKSV NRQDAGDYSC HAENSIAKDS ITHKLIVLAP PQSPHVTLSA 300
301 TTTDALTVKL KPHEGDTAPL HGYTLHYKPE FGEWETSEVS VDSQKHNIEG LLCGSRYQVY 360
361 ATGFNNIGAG EA
|
| Detection Method: | |
| Confidence: | 13.154902 |
| Match: | 1zlgA |
| Description: | No description for 1zlgA was found. |
|
Region A: Residues: [1482-1595] |
1 11 21 31 41 51
| | | | | |
1 SDILNTRTKG QKPKLPEKPR FIEVSSNSVS LHFKAWKDGG CPMSHFVVES KKRDQIEWNQ 60
61 ISNNVKPDNN YVVLDLEPAT WYNLRITAHN SAGFTVAEYD FATLTVTGGT IAPS
|
| Detection Method: | |
| Confidence: | 12.154902 |
| Match: | 1x3dA |
| Description: | Solution structure of the fibronectin type-III domain of human fibronectin type-III domain containing protein 3a |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| transmembrane receptor activity | 4.81256300373074 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| receptor activity | 4.66147271961356 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| cytokine binding | 4.43581512268554 | bayes_pls_golite062009 |
| cytokine receptor activity | 4.08668869714207 | bayes_pls_golite062009 |
| signal transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| molecular transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| growth factor binding | 3.39021787583547 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| interleukin-2 binding | 2.68205932397612 | bayes_pls_golite062009 |
| interleukin-7 binding | 2.52651471003365 | bayes_pls_golite062009 |
| receptor binding | 2.38673889309915 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 2.15011619378442 | bayes_pls_golite062009 |
| peptide hormone binding | 2.12033076929638 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| interleukin-12 binding | 1.99482977929342 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 1.99168831878759 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 1.99168831878759 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.9781930293417 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.9781930293417 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| cytokine activity | 1.93281236178924 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| interleukin-11 binding | 1.57103867592521 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 1.57103867592521 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.56410665522466 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| mercury ion binding | 1.46191698606762 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| growth factor activity | 1.16355032792247 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| heparin binding | 1.15000556789505 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 1.1057194345531 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 1.10508957821356 | bayes_pls_golite062009 |
| sialic acid binding | 0.992369242781511 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| interleukin-12 alpha subunit binding | 0.924116090838821 | bayes_pls_golite062009 |
| peptide binding | 0.92031154055894 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| growth hormone receptor activity | 0.840187286074179 | bayes_pls_golite062009 |
| pattern binding | 0.82756944920828 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.78428502513367 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| collagen binding | 0.593745877718282 | bayes_pls_golite062009 |
| ciliary neurotrophic factor binding | 0.578087868054051 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| polysaccharide binding | 0.54737137289904 | bayes_pls_golite062009 |
| hormone binding | 0.49524185948356 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor binding | 0.338520586013721 | bayes_pls_golite062009 |
| peptidase activator activity | 0.249363133780499 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protease binding | 0.12595904253108 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| sugar binding | 0.113922042820831 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
| interleukin-12 receptor binding | 0.0393437987205916 | bayes_pls_golite062009 |
|
Region A: Residues: [1596-1784] |
1 11 21 31 41 51
| | | | | |
1 RDLPELSAED TIRIILSNLN LVVPVVAALL VIIIAIIVIC ILRSKGNHHK DDVVYNQTMG 60
61 PGATLDKRRP DLRDELGYIA PPNRKLPPVP GSNYNTCDRI KRGRGGLRSN HSTWDPRRNP 120
121 NLYEELKAPP VPMHGNHYGH AHGNAECHYR HPGMEDEICP YATFHLLGFR EEMDPTKAMN 180
181 FQTFPHQNG
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1785-2013] |
1 11 21 31 41 51
| | | | | |
1 HAGPVPGHAG TMLPPGHPGH VHSRSGSQSM PRANRYQRKN SQGGQSSIYT PAPEYDDPAN 60
61 CAEEDQYRRY TRVNSQGGSL YSGPGPEYDD PANCAPEEDQ YGSQYGGPYG QPYDHYGSRG 120
121 SMGRRSIGSA RNPGNGSPEP PPPPPRNHDM SNSSFNDSKE SNEISEAECD RDHGPRGNYG 180
181 AVKRSPQPKD QRTTEEMRKL IERNETGPKQ LQLQQANGAG FTAYDTMAV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
