YRC Public Data Repository - Protein Structure Prediction

Protein:	RPIA_MOUSE
Organism:	Mus musculus
Length:	236 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPIA_MOUSE.

Description	E-value	Query Range	Subject Range
RPIA - ribose 5-phosphate isomerase A	342.0	[0..1]	[236..75]
ENSMMUT000000129... - null, null gi\|114578714 - gi\|114578714\|ref\|XP_525809.2\| PREDICTED: ribose 5-phosphate isomerase A (ribose 5-phosphate epimeras...	342.0	[0..1]	[236..75]
RPIA_MOUSE - Ribose-5-phosphate isomerase OS=Mus musculus GN=Rpia PE=1 SV=2	339.0	[0..1]	[236..68]
gi\|109473646, gi... - gi\|62647453\|ref\|XP_342708.2\| PREDICTED: similar to Ribose-5-phosphate isomerase (Phosphoriboisomeras...	338.0	[0..1]	[236..68]
RPIA - ribose 5-phosphate isomerase A gi\|109103776 - gi\|109103776\|ref\|XP_001094618.1\| PREDICTED: similar to Ribose-5-phosphate isomerase (Phosphoriboisom...	333.0	[0..1]	[236..1]
gi\|55250104, gi\|... - gi\|55925229\|ref\|NP_001007290.1\| ribose 5-phosphate isomerase A [Danio rerio], gi\|55250104\|gb\|AAH8554...	331.0	[0..4]	[235..42]
gi\|78369498, gi\|... - gi\|78369498\|ref\|NP_001030510.1\| ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase) [Bos t...	328.0	[0..1]	[236..1]
gi\|53136558, gi\|... - gi\|71896441\|ref\|NP_001026341.1\| ribose 5-phosphate isomerase A [Gallus gallus], gi\|53136558\|emb\|CAG3...	321.0	[0..4]	[234..2]

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Predicted Domain #1

Region A:
Residues: [1-236]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKAEEAKKL ASHTAVENHV KNNQVLGIGS GSTIVHAVQR IAERVKQENL DLICIPTSFQ  60
   61 ARQLILQYGL TLSDLDQHPE IDLAIDGADE VDAELNLIKG GGGCLTQEKI VAGYASRFIV 120
  121 IADFRKDSKN LGDRWHKGIP IEVIPMAYVP VSRAVAQKFG GEVELRMAVN KAGPVVTDNG 180
  181 NFILDWKFDR VHKWSEVNTA IKMTPGVVDT GLFINMAERV YFGMQDGSVN VREKPF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	77.69897
Match:	1lk5A
Description:	D-ribose-5-phosphate isomerase (RpiA), catalytic domain; D-ribose-5-phosphate isomerase (RpiA), lid domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribose-5-phosphate isomerase activity	2.23318567990318	bayes_pls_golite062009
6-phosphogluconolactonase activity	1.97756803122763	bayes_pls_golite062009
nucleic acid binding	1.15193795385115	bayes_pls_golite062009
binding	0.867979574569016	bayes_pls_golite062009
intramolecular oxidoreductase activity	0.61058174487002	bayes_pls_golite062009
transcription regulator activity	0.527142798518238	bayes_pls_golite062009
DNA binding	0.465566131334457	bayes_pls_golite062009
catalytic activity	0.424959044318554	bayes_pls_golite062009
glucosamine-6-phosphate deaminase activity	0.111185777194415	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	0.075853172283603	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: