YRC Public Data Repository - Protein Structure Prediction

Protein:	ETFB
Organism:	Homo sapiens
Length:	255 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ETFB.

Description	E-value	Query Range	Subject Range
gi\|49089300, gi\|... - gi\|67523567\|ref\|XP_659843.1\| hypothetical protein AN2239.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	3.0E-79	[2..255]	[648..906]
gi\|114328758, gi... - gi\|114328758\|ref\|YP_745915.1\| electron transfer flavoprotein beta-subunit [Granulibacter bethesdensi...	7.0E-79	[2..255]	[33..282]
ETFB_PONAB - Electron transfer flavoprotein subunit beta OS=Pongo abelii GN=ETFB PE=2 SV=3 ETFB_PONPY - Electron transfer flavoprotein subunit beta - Pongo pygmaeus (Orangutan)	3.0E-78	[1..255]	[1..255]
gi\|33597651 - gi\|33597651\|ref\|NP_885294.1\| electron transfer flavoprotein beta-subunit [Bordetella parapertussis 1... gi\|33576869, gi\|... - gi\|33602430\|ref\|NP_889990.1\| electron transfer flavoprotein beta-subunit [Bordetella bronchiseptica ... gi\|33574079 - gi\|33574079\|emb\|CAE38403.1\| electron transfer flavoprotein beta-subunit [Bordetella parapertussis]	3.0E-78	[4..255]	[18..265]
gi\|71042617, gi\|... - gi\|71042619\|pdb\|2A1U\|B Chain B, Crystal Structure Of The Human Etf E165betaa Mutant, gi\|71042617\|pdb...	4.0E-78	[1..255]	[1..255]
gi\|109125757, gi... - gi\|109125759\|ref\|XP_001116320.1\| PREDICTED: similar to electron-transfer-flavoprotein, beta polypept...	6.0E-78	[1..255]	[1..255]
ETFB_RAT - Electron transfer flavoprotein subunit beta OS=Rattus norvegicus GN=Etfb PE=2 SV=3	2.0E-77	[1..255]	[1..255]
ETFB_MOUSE - Electron transfer flavoprotein subunit beta OS=Mus musculus GN=Etfb PE=1 SV=3	2.0E-77	[1..255]	[1..255]

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Predicted Domain #1

Region A:
Residues: [1-255]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAELRVLVAV KRVIDYAVKI RVKPDRTGVV TDGVKHSMNP FCEIAVEEAV RLKEKKLVKE  60
   61 VIAVSCGPAQ CQETIRTALA MGADRGIHVE VPPAEAERLG PLQVARVLAK LAEKEKVDLV 120
  121 LLGKQAIDDD CNQTGQMTAG FLDWPQGTFA SQVTLEGDKL KVEREIDGGL ETLRLKLPAV 180
  181 VTADLRLNEP RYATLPNIMK AKKKKIEVIK PGDLGVDLTS KLSVISVEDP PQRTAGVKVE 240
  241 TTEDLVAKLK EIGRI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	80.09691
Match:	1efvB
Description:	Small, beta subunit of electron transfer flavoprotein ETFP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.91619517870463	bayes_pls_golite062009
nucleic acid binding	1.38436645708366	bayes_pls_golite062009
DNA binding	1.35936746868519	bayes_pls_golite062009
ligase activity	1.13489674466232	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.883268134837366	bayes_pls_golite062009
catalytic activity	0.828867994386867	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.724532065311415	bayes_pls_golite062009
electron carrier activity	0.40873603017227	bayes_pls_golite062009
transferase activity	0.40273889227698	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: