| Protein: | DHX8 |
| Organism: | Homo sapiens |
| Length: | 1220 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DHX8.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [7..1220] | [1..1214] |
|
|
0.0 | [1..1220] | [1..1244] |
|
|
0.0 | [13..1220] | [26..1233] |
|
|
0.0 | [15..1220] | [15..1216] |
|
|
0.0 | [19..1220] | [6..1210] |
|
|
0.0 | [11..1148] | [11..1148] |
|
Region A: Residues: [1-138] |
1 11 21 31 41 51
| | | | | |
1 MAVAVAMAGA LIGSEPGPAE ELAKLEYLSL VSKVCTELDN HLGINDKDLA EFVISLAEKN 60
61 TTFDTFKASL VKNGAEFTDS LISNLLRLIQ TMRPPAKPST SKDPVVKPKT EKEKLKELFP 120
121 VLCQPDNPSV RTMLDEDD
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [139-238] |
1 11 21 31 41 51
| | | | | |
1 VKVAVDVLKE LEALMPSAAG QEKQRDAEHR DRTKKKKRSR SRDRNRDRDR DRERNRDRDH 60
61 KRRHRSRSRS RSRTRERNKV KSRYRSRSRS QSPPKDRKDR
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [239-500] |
1 11 21 31 41 51
| | | | | |
1 DKYGERNLDR WRDKHVDRPP PEEPTIGDIY NGKVTSIMQF GCFVQLEGLR KRWEGLVHIS 60
61 ELRREGRVAN VADVVSKGQR VKVKVLSFTG TKTSLSMKDV DQETGEDLNP NRRRNLVGET 120
121 NEETSMRNPD RPTHLSLVSA PEVEDDSLER KRLTRISDPE KWEIKQMIAA NVLSKEEFPD 180
181 FDEETGILPK VDDEEDEDLE IELVEEEPPF LRGHTKQSMD MSPIKIVKNP DGSLSQAAMM 240
241 QSALAKERRE LKQAQREAEM DS
|
| Detection Method: | |
| Confidence: | 2.27 |
| Match: | 1yz6A |
| Description: | Crystal structure of intact alpha subunit of aIF2 from Pyrococcus abyssi |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [501-560] |
1 11 21 31 41 51
| | | | | |
1 IPMGLNKHWV DPLPDAEGRQ IAANMRGIGM MPNDIPEWKK HAFGGNKASY GKKTQMSILE 60
61
|
| Detection Method: | |
| Confidence: | 66.221849 |
| Match: | 2db3A |
| Description: | No description for 2db3A was found. |
|
Region A: Residues: [561-1129] |
1 11 21 31 41 51
| | | | | |
1 QRESLPIYKL KEQLVQAVHD NQILIVIGET GSGKTTQITQ YLAEAGYTSR GKIGCTQPRR 60
61 VAAMSVAKRV SEEFGCCLGQ EVGYTIRFED CTSPETVIKY MTDGMLLREC LIDPDLTQYA 120
121 IIMLDEAHER TIHTDVLFGL LKKTVQKRQD MKLIVTSATL DAVKFSQYFY EAPIFTIPGR 180
181 TYPVEILYTK EPETDYLDAS LITVMQIHLT EPPGDILVFL TGQEEIDTAC EILYERMKSL 240
241 GPDVPELIIL PVYSALPSEM QTRIFDPAPP GSRKVVIATN IAETSLTIDG IYYVVDPGFV 300
301 KQKVYNSKTG IDQLVVTPIS QAQAKQRAGR AGRTGPGKCY RLYTERAYRD EMLTTNVPEI 360
361 QRTNLASTVL SLKAMGINDL LSFDFMDAPP METLITAMEQ LYTLGALDDE GLLTRLGRRM 420
421 AEFPLEPMLC KMLIMSVHLG CSEEMLTIVS MLSVQNVFYR PKDKQALADQ KKAKFHQTEG 480
481 DHLTLLAVYN SWKNNKFSNP WCYENFIQAR SLRRAQDIRK QMLGIMDRHK LDVVSCGKST 540
541 VRVQKAICSG FFRNAAKKDP QEGYRTLID
|
| Detection Method: | |
| Confidence: | 33.30103 |
| Match: | 2p6rA |
| Description: | No description for 2p6rA was found. |
| Term | Confidence | Notes |
| 4.704140727858 | bayes_pls_golite062009 | |
| binding | 2.44689197844883 | bayes_pls_golite062009 |
| RNA binding | 2.29590582680214 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.57653963868443 | bayes_pls_golite062009 |
| RNA helicase activity | 1.42791449104435 | bayes_pls_golite062009 |
| nucleic acid binding | 1.41477043612798 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 1.39335733374328 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 1.36724390116598 | bayes_pls_golite062009 |
| DNA binding | 1.11699929651302 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| transcription regulator activity | 0.989226939888218 | bayes_pls_golite062009 |
| mRNA binding | 0.76699944561918 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.652333406433794 | bayes_pls_golite062009 |
| helicase activity | 0.6191010101321 | bayes_pls_golite062009 |
| motor activity | 0.61636596887462 | bayes_pls_golite062009 |
| structural molecule activity | 0.596382945962261 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.461763181659193 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.458831409927227 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.455976987338331 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.422944846459286 | bayes_pls_golite062009 |
| snRNA binding | 0.418985924846052 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 0.29664013896754 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 0.29664013896754 | bayes_pls_golite062009 |
| translation release factor activity | 0.178286731022211 | bayes_pls_golite062009 |
| translation termination factor activity | 0.151456842619444 | bayes_pls_golite062009 |
| nucleotide binding | 0.114848452385726 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.10713474095071 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.0916519414118148 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.0915913646217636 | bayes_pls_golite062009 |
| protein binding | 0.071010918255742 | bayes_pls_golite062009 |
| transcription factor activity | 0.0434163635422169 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.0272673919333979 | bayes_pls_golite062009 |
|
Region A: Residues: [1130-1220] |
1 11 21 31 41 51
| | | | | |
1 QQVVYIHPSS ALFNRQPEWV VYHELVLTTK EYMREVTTID PRWLVEFAPA FFKVSDPTKL 60
61 SKQKKQQRLE PLYNRYEEPN AWRISRAFRR R
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
