YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: SWH1
Organism: Saccharomyces cerevisiae
Length: 1188 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SWH1.

Description E-value Query
Range
Subject
Range
SWH1 - Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats; localizes to the G...
0.0 [1..1188] [1..1188]
gi|67904152, gi|... - gi|67904152|ref|XP_682332.1| hypothetical protein AN9063.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
0.0 [20..1188] [121..1243]
OSBL1_RAT - Oxysterol-binding protein-related protein 1 OS=Rattus norvegicus GN=Osbpl1a PE=1 SV=1
0.0 [267..1188] [10..950]
gi|38567327, gi|... - gi|38567327|emb|CAE76615.1| related to oxysterol-binding protein [Neurospora crassa], gi|32408555|re...
gi|85074703 - gi|85074703|ref|XP_965719.1| hypothetical protein NCU00579 [Neurospora crassa OR74A]
0.0 [18..1188] [151..1235]
gi|17529999 - gi|17529999|gb|AAL40663.1|AF392450_1 oxysterol-binding protein-like protein OSBPL1B [Homo sapiens]
0.0 [267..1188] [10..950]
gi|46128417, gi|... - gi|46128417|ref|XP_388762.1| hypothetical protein FG08586.1 [Gibberella zeae PH-1], gi|42549771|gb|E...
0.0 [15..1188] [152..1266]

Back

Predicted Domain #1
Region A:
Residues: [1-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQPDLSSVA ISKPLLKLKL LDALRQGSFP NLQDLLKKQF QPLDDPNVQQ VLHLMLHYAV  60
   61 QVAPMAVIKE IVHHWVSTTN TTFLNIHLDL NERDSNGNTP LHIAAYQSRG DIVAFLLDQP 120
  121 TINDCVLNNS HLQAIEMCKN LNIAQMMQVK RSTYVAETAQ EFRTAFNNRD FGHLESILSS 180
  181 PRNAELLDIN GMDPETGDTV LHEFVKKRDV IMCRWLLEHG ADPFKRDRKG KLPIELVRKV 240
  241 NENDTATSTK IAIDIELKKL LERATREQSV IDVTNNNLHE APTYKGYLKK WTNFAQGYKL 300
  301 RWFILSSDGK LSYYIDQADT KNACRGSLNM SSCSLHLDSS EKLKFEIIGG NNGVIRWHLK 360
  361 GNHPIETNRW VWAIQGAIRY AKDREILLHN GP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.0
Match: 1n11A_
Description: Ankyrin-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.46128459961519 bayes_pls_golite062009
protein binding 1.6716587413544 bayes_pls_golite062009
transporter activity 1.62618963155033 bayes_pls_golite062009
transmembrane transporter activity 1.36262284136123 bayes_pls_golite062009
substrate-specific transporter activity 0.970617674606391 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.786064957992193 bayes_pls_golite062009
ion transmembrane transporter activity 0.370811261525551 bayes_pls_golite062009
transcription regulator activity 0.271428013908666 bayes_pls_golite062009
nucleic acid binding 0.106792084948545 bayes_pls_golite062009
cytoskeletal protein binding 0.0888208413153098 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [393-518]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YSPSLALSHG LSSKVSNKEN LHATSKRLTK SPHLSKSTLT QNDHDNDDDS TNNNNNKSNN  60
   61 DYDDNNNNNN NDDDDYDDDD ESRPLIEPLP LISSRSQSLS EITPGPHSRK STVSSTRAAD 120
  121 IPSDDE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [519-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYSEDDSDDD GNSSYTMENG GENDGDEDLN AIYGPYIQKL HMLQRSISIE LASLNELLQD  60
   61 KQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [581-724]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QHDEYWNTVN TSIETVSEFF DKLNRLTSQR EKRMIAQMTK QRDVNNVWIQ SVKDLEMELV  60
   61 DKDEKLVALD KERKNLKKML QKKLNNQPQV ETEANEESDD ANSMIKGSQE STNTLEEIVK 120
  121 FIEATKESDE DSDADEFFDA EEAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [725-855]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDKKANDSED LTTNKETPAN AKPQEEAPED ESLIVISSPQ VEKKNQLLKE GSFVGYEDPV  60
   61 RTKLALDEDN RPKIGLWSVL KSMVGQDLTK LTLPVSFNEP TSLLQRVSED IEYSHILDQA 120
  121 ATFEDSSLRM L

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
oxysterol binding 5.62675037461468 bayes_pls_golite062009
sterol binding 4.18891468109664 bayes_pls_golite062009
3.02967613614595 bayes_pls_golite062009
steroid binding 2.54679035876403 bayes_pls_golite062009
binding 2.38976505793668 bayes_pls_golite062009
phosphoinositide binding 1.88386267925687 bayes_pls_golite062009
lipid binding 1.8520231230392 bayes_pls_golite062009
phospholipid binding 1.53854106315366 bayes_pls_golite062009
cholesterol binding 0.644339278395346 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [856-961]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YVAAFTASMY ASTTNRVSKP FNPLLGETFE YARTDGQYRF FTEQVSHHPP ISATWTESPK  60
   61 WDFYGECNVD SSFNGRTFAV QHLGLWYITI RPDHNISVPE ETYSWK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [962-1086]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPNNTVIGIL MGKPQVDNSG DVKVTNHTTG DYCMLHYKAH GWTSAGAYEV RGEVFNKDDK  60
   61 KLWVLGGHWN DSIYGKKVTA RGGELTLDRI KTANSATGGP KLDGSKFLIW KANERPSVPF 120
  121 NLTSF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1087-1188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALTLNALPPH LIPYLAPTDS RLRPDQRAME NGEYDKAAAE KHRVEVKQRA AKKEREQKGE  60
   61 EYRPKWFVQE EHPVTKSLYW KFNGEYWNKR KNHDFKDCAD IF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle