YRC Public Data Repository - Protein Structure Prediction

Protein:	contaminant_INT-...
Organism:	Homo sapiens
Length:	385 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for contaminant_INT-....

Description	E-value	Query Range	Subject Range
gi\|76678522 - gi\|76678522\|ref\|XP_588377.2\| PREDICTED: similar to SCCA2/SCCA1 fusion protein [Bos taurus]	388.0	[0..2]	[385..27]
gi\|109069435 - gi\|109069435\|ref\|XP_001091156.1\| PREDICTED: serine (or cysteine) proteinase inhibitor, clade B (oval...	388.0	[0..2]	[385..3]
gi\|481621 - gi\|481621\|pir\|\|S38962 serpin - pig	387.0	[0..3]	[385..4]
gi\|114605208 - gi\|114605208\|ref\|XP_001160054.1\| PREDICTED: serine (or cysteine) proteinase inhibitor, clade B (oval...	383.0	[0..2]	[385..3]
gi\|34875368, gi\|... - gi\|56090431\|ref\|NP_001007733.1\| similar to SPI6 [Rattus norvegicus], gi\|50926066\|gb\|AAH79063.1\| Seri...	382.0	[0..2]	[385..3]
gi\|51092274, gi\|... - gi\|51092274\|ref\|NP_033152.2\| serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member ...	382.0	[0..3]	[385..4]
gi\|30584889, gi\|... - gi\|61371906\|gb\|AAX43753.1\| serine or cysteine proteinase inhibitor clade B member 9 [synthetic const...	382.0	[0..2]	[385..3]
gi\|123979742, gi... - gi\|60655129\|gb\|AAX32128.1\| serine or cysteine proteinase inhibitor clade B member 9 [synthetic const... SERPINB9 - serpin peptidase inhibitor, clade B (ovalbumin), member 9	382.0	[0..2]	[385..3]
gi\|74003800 - gi\|74003800\|ref\|XP_855831.1\| PREDICTED: similar to Cytoplasmic antiproteinase 3 (CAP3) (CAP-3) (Prot...	380.0	[0..2]	[385..3]

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Predicted Domain #1

Region A:
Residues: [1-385]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSIGAASMEF CFDVFKELKV HHANENIFYC PIAIMSALAM VYLGAKDSTR TQINKVVRFD  60
   61 KLPGFGDSIE AQCGTSVNVH SSLRDILNQI TKPNDVYSFS LASRLYAEER YPILPEYLQC 120
  121 VKELYRGGLE PINFQTAADQ ARELINSWVE SQTNGIIRNV LQPSSVDSQT AMVLVNAIVF 180
  181 KGLWEKAFKD EDTQAMPFRV TEQESKPVQM MYQIGLFRVA SMASEKMKIL ELPFASGTMS 240
  241 MLVLLPDEVS GLEQLESIIN FEKLTEWTSS NVMEERKIKV YLPRMKMEEK YNLTSVLMAM 300
  301 GITDVFSSSA NLSGISSAES LKISQAVHAA HAEINEAGRE VVGSAEAGVD AASVSEEFRA 360
  361 DHPFLFCIKH IATNAVLFFG RCVSP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	98.522879
Match:	1jtiA
Description:	Ovalbumin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
serine-type endopeptidase inhibitor activity	6.13717785773502	bayes_pls_golite062009
peptidase inhibitor activity	6.07523919900796	bayes_pls_golite062009
endopeptidase inhibitor activity	6.01194624525726	bayes_pls_golite062009
enzyme inhibitor activity	3.67290572457064	bayes_pls_golite062009
protease binding	2.69747551802498	bayes_pls_golite062009
enzyme regulator activity	2.47388770421699	bayes_pls_golite062009
binding	2.02049891212041	bayes_pls_golite062009
protein binding	1.90236643189719	bayes_pls_golite062009
glycosaminoglycan binding	1.61358221181146	bayes_pls_golite062009
nucleic acid binding	1.46959492426289	bayes_pls_golite062009
DNA binding	1.31854786197421	bayes_pls_golite062009
transporter activity	1.29851101299849	bayes_pls_golite062009
heparin binding	1.21540270241849	bayes_pls_golite062009
receptor activity	1.1966923866485	bayes_pls_golite062009
transmembrane receptor activity	1.14424818451335	bayes_pls_golite062009
signal transducer activity	1.12659599250323	bayes_pls_golite062009
molecular transducer activity	1.12659599250323	bayes_pls_golite062009
transmembrane transporter activity	1.07876412297114	bayes_pls_golite062009
receptor binding	1.0390886965673	bayes_pls_golite062009
polysaccharide binding	0.99559313679422	bayes_pls_golite062009
type 2 angiotensin receptor binding	0.92552398196189	bayes_pls_golite062009
thyroid hormone transmembrane transporter activity	0.812950479764802	bayes_pls_golite062009
collagen binding	0.307023895861541	bayes_pls_golite062009
active transmembrane transporter activity	0.262958899612658	bayes_pls_golite062009
growth factor activity	0.21183671094477	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: