YRC Public Data Repository - Protein Structure Prediction

Protein:	LTP1
Organism:	Saccharomyces cerevisiae
Length:	161 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LTP1.

Description	E-value	Query Range	Subject Range
gi\|151942856 - gi\|151942856\|gb\|EDN61202.1\| protein tyrosine phosphatase [Saccharomyces cerevisiae YJM789] gi\|190408009 - gi\|190408009\|gb\|EDV11274.1\| 18 kDa phosphotyrosine phosphatase [Saccharomyces cerevisiae RM11-1a] LTP1 - Protein phosphotyrosine phosphatase of unknown cellular role; activated by adenine PPAL_YEAST - Low molecular weight phosphotyrosine protein phosphatase OS=Saccharomyces cerevisiae (strain ATCC 20...	4.0E-52	[1..161]	[1..161]
ACP1 - acid phosphatase 1, soluble	2.0E-49	[4..159]	[2..155]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	6.0E-49	[4..159]	[2..155]
gi\|257210 - gi\|257210\|gb\|AAB23589.1\| low M(r) phosphotyrosine protein phosphatase isoenzyme AcP2 [rats, liver, P... IPI:IPI00231705.... - Ensembl_locations(Chr-bp):6-41523421 Splice isoform ACP2 of P41498	8.0E-49	[4..159]	[4..157]
gi\|16943635, gi\|... - gi\|16943635\|gb\|AAK83456.1\| low molecular weight protein tyrosine phosphatase 1a [Xenopus laevis], gi...	1.0E-48	[1..159]	[1..157]

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Predicted Domain #1

Region A:
Residues: [1-161]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIEKPKISV AFICLGNFCR SPMAEAIFKH EVEKANLENR FNKIDSFGTS NYHVGESPDH  60
   61 RTVSICKQHG VKINHKGKQI KTKHFDEYDY IIGMDESNIN NLKKIQPEGS KAKVCLFGDW 120
  121 NTNDGTVQTI IEDPWYGDIQ DFEYNFKQIT YFSKQFLKKE L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	917.228787
Match:	1d1pA_
Description:	Tyrosine phosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoprotein phosphatase activity	6.88246946508693	bayes_pls_golite062009
phosphatase activity	6.45415826301085	bayes_pls_golite062009
phosphoric ester hydrolase activity	6.24793868976995	bayes_pls_golite062009
protein tyrosine phosphatase activity	5.42677419561083	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	5.27901564747165	bayes_pls_golite062009
hydrolase activity	3.65742648154352	bayes_pls_golite062009
catalytic activity	1.99182579317454	bayes_pls_golite062009
binding	1.7522117458664	bayes_pls_golite062009
transcription regulator activity	0.628751319213679	bayes_pls_golite062009
acid phosphatase activity	0.62303289859123	bayes_pls_golite062009
nucleic acid binding	0.557666750724006	bayes_pls_golite062009
DNA binding	0.357202336581626	bayes_pls_golite062009
protein binding	0.332591807861153	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: