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View Structure Prediction Details

Protein: SSO1
Organism: Saccharomyces cerevisiae
Length: 290 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SSO1.

Description E-value Query
Range
Subject
Range
gi|303605 - gi|303605|dbj|BAA03436.1| epimorphin [Homo sapiens]
2.0E-52 [3..289] [1..290]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-52 [2..287] [10..297]
STX1B_MOUSE - Syntaxin-1B OS=Mus musculus GN=Stx1b PE=1 SV=1
gi|251471 - gi|251471|gb|AAB22526.1| syntaxin, P35B [rats, brain, Peptide, 288 aa]
ENSCJAT00000005845 - null
gi|114662156 - gi|114662156|ref|XP_001145497.1| PREDICTED: similar to syntaxin B [Pan troglodytes]
STX1B - syntaxin 1B
STX1B_RAT - Syntaxin-1B OS=Rattus norvegicus GN=Stx1b PE=1 SV=1
6.0E-51 [3..287] [1..286]
STX1B_SHEEP - Syntaxin-1B OS=Ovis aries GN=STX1B PE=2 SV=1
STX1B_BOVIN - Syntaxin-1B OS=Bos taurus GN=STX1B PE=1 SV=1
8.0E-51 [3..287] [1..286]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
2.0E-50 [3..287] [1..286]
gi|18859443, gi|... - gi|7107406|gb|AAF36403.1|AF229154_1 syntaxin 1B [Danio rerio], gi|18859443|ref|NP_571598.1| syntaxin...
4.0E-50 [3..287] [1..286]
gi|7595847, gi|7... - gi|7595847|gb|AAF64478.1| syntaxin 1A [Macaca mulatta], gi|74136291|ref|NP_001028037.1| syntaxin 1B ...
4.0E-50 [3..287] [1..287]
STX1A_MOUSE - Syntaxin-1A OS=Mus musculus GN=Stx1a PE=1 SV=3
6.0E-50 [3..287] [1..287]

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Predicted Domain #1
Region A:
Residues: [1-140]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYNNPYQLE TPFEESYELD EGSSAIGAEG HDFVGFMNKI SQINRDLDKY DHTINQVDSL  60
   61 HKRLLTEVNE EQASHLRHSL DNFVAQATDL QFKLKNEIKS AQRDGIHDTN KQAQAENSRQ 120
  121 RFLKLIQDYR IVDSNYKEEN 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [196-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RHQELLKLEK SMAELTQLFN DMEELVIEQQ ENVDVIDKNV EDAQLDVEQG VGHTDKAVKS  60
   61 ARKARKNKIR CWLIVFAIIV VVVVVVVVPA VVKTR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 902.69897
Match: 1fioA_
Description: Sso1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphatidic acid binding 8.51970136264329 bayes_pls_golite062009
SNAP receptor activity 3.50393203740159 bayes_pls_golite062009
binding 2.33192450173199 bayes_pls_golite062009
calcium-dependent protein binding 1.88288628726104 bayes_pls_golite062009
SNARE binding 1.85060343142976 bayes_pls_golite062009
transporter activity 1.74189664015129 bayes_pls_golite062009
protein binding 1.61683263008775 bayes_pls_golite062009
substrate-specific transporter activity 1.49085442233849 bayes_pls_golite062009
protein transporter activity 1.29299397166394 bayes_pls_golite062009
transmembrane transporter activity 1.13101548288086 bayes_pls_golite062009
calcium channel inhibitor activity 0.90937110343252 bayes_pls_golite062009
extracellular ligand-gated ion channel activity 0.86350507004267 bayes_pls_golite062009
excitatory extracellular ligand-gated ion channel activity 0.86350507004267 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.643064875848901 bayes_pls_golite062009
gated channel activity 0.621670335227137 bayes_pls_golite062009
ligand-gated ion channel activity 0.41937155561589 bayes_pls_golite062009
ligand-gated channel activity 0.41937155561589 bayes_pls_golite062009
ion transmembrane transporter activity 0.370484918396857 bayes_pls_golite062009
passive transmembrane transporter activity 0.0647076360772156 bayes_pls_golite062009
channel activity 0.0647076360772156 bayes_pls_golite062009
substrate-specific channel activity 0.0435980899803177 bayes_pls_golite062009
phospholipid binding 0.0172309833091902 bayes_pls_golite062009
cytoskeletal protein binding 0.00476738027966683 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [141-195]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEQAKRQYMI IQPEATEDEV EAAISDVGGQ QIFSQALLNA NRRGEAKTAL AEVQA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 902.69897
Match: 1fioA_
Description: Sso1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle