YRC Public Data Repository - Protein Structure Prediction

Protein:	NIP7
Organism:	Saccharomyces cerevisiae
Length:	181 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NIP7.

Description	E-value	Query Range	Subject Range
NIP7 - nuclear import 7 homolog (S. cerevisiae) NIP7_PONPY - 60S ribosome subunit biogenesis protein NIP7 homolog - Pongo pygmaeus (Orangutan) NIP7_PONAB - 60S ribosome subunit biogenesis protein NIP7 homolog OS=Pongo abelii GN=NIP7 PE=2 SV=1 gi\|123995231, gi... - gi\|123995231\|gb\|ABM85217.1\| nuclear import 7 homolog (S. cerevisiae) [synthetic construct], gi\|12398... ENSPTRT00000044085 - null gi\|90082984 - gi\|90082984\|dbj\|BAE90574.1\| unnamed protein product [Macaca fascicularis]	2.0E-88	[1..179]	[1..179]
NIP7_RAT - 60S ribosome subunit biogenesis protein NIP7 homolog OS=Rattus norvegicus GN=Nip7 PE=2 SV=1	2.0E-88	[1..179]	[1..179]
NIP7_MOUSE - 60S ribosome subunit biogenesis protein NIP7 homolog OS=Mus musculus GN=Nip7 PE=1 SV=1	3.0E-88	[1..179]	[1..179]
NIP7_SCHPO - 60S ribosome subunit biogenesis protein nip7 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ... SPCC320.11c - RNA-binding protein	3.0E-83	[1..180]	[1..180]
gi\|190407752 - gi\|190407752\|gb\|EDV11017.1\| 60S ribosome subunit biogenesis protein NIP7 [Saccharomyces cerevisiae R... gi\|151942590 - gi\|151942590\|gb\|EDN60936.1\| nuclear import-related protein [Saccharomyces cerevisiae YJM789] NIP7_YEAST - 60S ribosome subunit biogenesis protein NIP7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c... NIP7 - Nucleolar protein required for 60S ribosome subunit biogenesis, constituent of 66S pre-ribosomal par...	5.0E-79	[1..181]	[1..181]
CE08687 - status:Confirmed UniProt:P91154 protein_id:AAB37628.1	1.0E-77	[1..179]	[1..179]
CG7006-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7006 (CG7006, FBgn0039233). It is a protein... gi\|220954436, gi... - gi\|220954436\|gb\|ACL89761.1\| CG7006-PA [synthetic construct], gi\|220944648\|gb\|ACL84867.1\| CG7006-PA [...	4.0E-77	[1..180]	[1..180]
gi\|66853678, gi\|... - gi\|71002718\|ref\|XP_756040.1\| 60S ribosome biogenesis protein Nip7 [Aspergillus fumigatus Af293], gi\|... gi\|159130094 - gi\|159130094\|gb\|EDP55208.1\| 60S ribosome biogenesis protein Nip7, putative [Aspergillus fumigatus A1... gi\|28394453 - gi\|28394453\|gb\|AAM08680.1\| Nip7p [Aspergillus fumigatus]	8.0E-71	[1..174]	[1..178]
gi\|85083988 - gi\|85083988\|ref\|XP_957229.1\| hypothetical protein [Neurospora crassa OR74A] gi\|32403156, gi\|... - gi\|32403156\|ref\|XP_322191.1\| hypothetical protein [Neurospora crassa], gi\|28918317\|gb\|EAA27993.1\| hy...	5.0E-70	[1..180]	[1..204]

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Predicted Domain #1

Region A:
Residues: [1-181]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRQLTEEETK VVFEKLAGYI GRNISFLVDN KELPHVFRLQ KDRVYYVPDH VAKLATSVAR  60
   61 PNLMSLGICL GKFTKTGKFR LHITSLTVLA KHAKYKIWIK PNGEMPFLYG NHVLKAHVGK 120
  121 MSDDIPEHAG VIVFAMNDVP LGFGVSAKST SESRNMQPTG IVAFRQADIG EYLRDEDTLF 180
  181 T

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	6.552842
Match:	PF03657
Description:	Uncharacterised protein family (UPF0113)

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
RNA binding	2.67504868533195	bayes_pls_golite062009
binding	1.85616760502339	bayes_pls_golite062009
nucleic acid binding	1.26170105245043	bayes_pls_golite062009
transcription regulator activity	1.25899985044692	bayes_pls_golite062009
DNA binding	1.00086161863786	bayes_pls_golite062009
transcription factor activity	0.459074630080185	bayes_pls_golite062009
protein binding	0.377070376016177	bayes_pls_golite062009
ligase activity	0.365702917579223	bayes_pls_golite062009
catalytic activity	0.147263815852997	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: