YRC Public Data Repository - Protein Structure Prediction

Protein:	NIP7
Organism:	Saccharomyces cerevisiae
Length:	181 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NIP7.

Description	E-value	Query Range	Subject Range
NIP7 - nuclear import 7 homolog (S. cerevisiae) NIP7_PONPY - 60S ribosome subunit biogenesis protein NIP7 homolog - Pongo pygmaeus (Orangutan) NIP7_PONAB - 60S ribosome subunit biogenesis protein NIP7 homolog OS=Pongo abelii GN=NIP7 PE=2 SV=1 gi\|123995231, gi... - gi\|123995231\|gb\|ABM85217.1\| nuclear import 7 homolog (S. cerevisiae) [synthetic construct], gi\|12398... ENSPTRT00000044085 - null gi\|90082984 - gi\|90082984\|dbj\|BAE90574.1\| unnamed protein product [Macaca fascicularis]	2.0E-88	[1..179]	[1..179]
NIP7_RAT - 60S ribosome subunit biogenesis protein NIP7 homolog OS=Rattus norvegicus GN=Nip7 PE=2 SV=1	2.0E-88	[1..179]	[1..179]
NIP7_MOUSE - 60S ribosome subunit biogenesis protein NIP7 homolog OS=Mus musculus GN=Nip7 PE=1 SV=1	3.0E-88	[1..179]	[1..179]
NIP7_SCHPO - 60S ribosome subunit biogenesis protein nip7 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ... SPCC320.11c - RNA-binding protein	3.0E-83	[1..180]	[1..180]
gi\|190407752 - gi\|190407752\|gb\|EDV11017.1\| 60S ribosome subunit biogenesis protein NIP7 [Saccharomyces cerevisiae R... gi\|151942590 - gi\|151942590\|gb\|EDN60936.1\| nuclear import-related protein [Saccharomyces cerevisiae YJM789] NIP7_YEAST - 60S ribosome subunit biogenesis protein NIP7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c... NIP7 - Nucleolar protein required for 60S ribosome subunit biogenesis, constituent of 66S pre-ribosomal par...	5.0E-79	[1..181]	[1..181]
CE08687 - status:Confirmed UniProt:P91154 protein_id:AAB37628.1	1.0E-77	[1..179]	[1..179]
CG7006-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7006 (CG7006, FBgn0039233). It is a protein... gi\|220954436, gi... - gi\|220954436\|gb\|ACL89761.1\| CG7006-PA [synthetic construct], gi\|220944648\|gb\|ACL84867.1\| CG7006-PA [...	4.0E-77	[1..180]	[1..180]
gi\|66853678, gi\|... - gi\|71002718\|ref\|XP_756040.1\| 60S ribosome biogenesis protein Nip7 [Aspergillus fumigatus Af293], gi\|... gi\|159130094 - gi\|159130094\|gb\|EDP55208.1\| 60S ribosome biogenesis protein Nip7, putative [Aspergillus fumigatus A1... gi\|28394453 - gi\|28394453\|gb\|AAM08680.1\| Nip7p [Aspergillus fumigatus]	8.0E-71	[1..174]	[1..178]
gi\|85083988 - gi\|85083988\|ref\|XP_957229.1\| hypothetical protein [Neurospora crassa OR74A] gi\|32403156, gi\|... - gi\|32403156\|ref\|XP_322191.1\| hypothetical protein [Neurospora crassa], gi\|28918317\|gb\|EAA27993.1\| hy...	5.0E-70	[1..180]	[1..204]

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Predicted Domain #1

Region A:
Residues: [1-181]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRQLTEEETK VVFEKLAGYI GRNISFLVDN KELPHVFRLQ KDRVYYVPDH VAKLATSVAR  60
   61 PNLMSLGICL GKFTKTGKFR LHITSLTVLA KHAKYKIWIK PNGEMPFLYG NHVLKAHVGK 120
  121 MSDDIPEHAG VIVFAMNDVP LGFGVSAKST SESRNMQPTG IVAFRQADIG EYLRDEDTLF 180
  181 T

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	6.552842
Match:	PF03657
Description:	Uncharacterised protein family (UPF0113)

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
RNA binding	2.67504868533195	bayes_pls_golite062009
binding	1.85616760502339	bayes_pls_golite062009
nucleic acid binding	1.26170105245043	bayes_pls_golite062009
transcription regulator activity	1.25899985044692	bayes_pls_golite062009
DNA binding	1.00086161863786	bayes_pls_golite062009
transcription factor activity	0.459074630080185	bayes_pls_golite062009
protein binding	0.377070376016177	bayes_pls_golite062009
ligase activity	0.365702917579223	bayes_pls_golite062009
catalytic activity	0.147263815852997	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: