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View Structure Prediction Details

Protein: KAP120
Organism: Saccharomyces cerevisiae
Length: 1032 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KAP120.

Description E-value Query
Range
Subject
Range
KA120_YEAST - Importin beta-like protein KAP120 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KAP120...
KAP120 - Karyopherin responsible for the nuclear import of ribosome maturation factor Rfp1p
0.0 [1..1032] [1..1032]
gi|123995715, gi... - gi|157928880|gb|ABW03725.1| importin 11 [synthetic construct], gi|123995715|gb|ABM85459.1| importin ...
IPO11 - importin 11
0.0 [8..1023] [1..972]
IPO11_MOUSE - Importin-11 OS=Mus musculus GN=Ipo11 PE=1 SV=1
0.0 [8..1023] [1..972]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [8..925] [1..861]
gi|28302264 - gi|28302264|gb|AAH46568.1| MGC52556 protein [Xenopus laevis]
0.0 [8..925] [1..861]

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Predicted Domain #1
Region A:
Residues: [1-702]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSLNELNL VQVLEQASNP QHIRSDVQKL AEQQLRQWET QAGFHYLLQS IYLNLSNSLQ  60
   61 IRWLAVIQFK NGVDKYWRST RINAIPKDEK ASIRGRLFEM IDEQNNQLCI QNAQASARIA 120
  121 RLDFPVEWPT LFEDLENLLN DEIIRKDSVK IYNILMHINQ IVKVLGTARI GRCRPAMQSK 180
  181 VPLILPLIVR IYLQSFEEWT TSSNLNYEDL SSLQVSYLAL KVLRRIICEG YDRPQTDQSV 240
  241 CDFIKLSVSH FEMLISNHEN FKKFDIYEKF IKCLGKLYFN LVTGSPANFI LLPCSTQILI 300
  301 TYTRLIFDKA PKVYRENSDV TGDFWEQTAI RGLLILKRVI NFIHKKGAIT LKARSDKLTI 360
  361 DASINKINTE FLNENLITRL VDTLMEWYLR LRPTELENWF MDPEEWINEQ MATSYEYQIR 420
  421 PCAENVFQDL MNTFSELLVP YLLKKIENDA SKLSNSLDDF LRKDAIYASF QLSASAVSEM 480
  481 VDFDRLLIQV FLPEATNTNI SGDELRIIRR RVALIINEWS TVKCSEESKS LCYKLFTNFL 540
  541 TDEDDKVVLL TTVQTVRTMV DDWNFNKDTF QPFLTENVHL LLRKILPSVS LTETRLYVLN 600
  601 TLSDIIIQTK PLISRDLLVE ILQIIPNLWE IATNNASEAI LANALLRLLR NLVSSLGSQS 660
  661 HLTWDIAIPV VALACDPSSM QYQLLSEDGY ELWGMLLQNF SS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
protein transporter activity 4.58709163830613 bayes_pls_golite062009
binding 3.0667965351474 bayes_pls_golite062009
protein transmembrane transporter activity 2.74547353635661 bayes_pls_golite062009
transporter activity 2.48700774379895 bayes_pls_golite062009
nucleic acid binding 2.34284977509828 bayes_pls_golite062009
substrate-specific transporter activity 2.26725422172281 bayes_pls_golite062009
nuclear export signal receptor activity 2.13470398426489 bayes_pls_golite062009
nuclear localization sequence binding 1.91487015967262 bayes_pls_golite062009
transcription regulator activity 1.76231475025891 bayes_pls_golite062009
protein binding 1.73688475473996 bayes_pls_golite062009
DNA binding 1.62032607987786 bayes_pls_golite062009
transmembrane transporter activity 1.28481004323799 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.09652988954158 bayes_pls_golite062009
transcription factor activity 0.923253759652909 bayes_pls_golite062009
structural molecule activity 0.908029258648777 bayes_pls_golite062009
translation initiation factor activity 0.83079633551839 bayes_pls_golite062009
translation regulator activity 0.82193201542158 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.803700928110921 bayes_pls_golite062009
molecular transducer activity 0.662662274021266 bayes_pls_golite062009
signal transducer activity 0.662662274021266 bayes_pls_golite062009
signal sequence binding 0.57106697498903 bayes_pls_golite062009
mRNA binding 0.46864854653143 bayes_pls_golite062009
RNA binding 0.40024158562931 bayes_pls_golite062009
active transmembrane transporter activity 0.252495966234234 bayes_pls_golite062009
ion transmembrane transporter activity 0.248585912061178 bayes_pls_golite062009
primary active transmembrane transporter activity 0.226380819487924 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.217517113570989 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.178770060806735 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.175241020572885 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.174922130116569 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.100181463251306 bayes_pls_golite062009
pyrophosphatase activity 0.0635404099346928 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0548082069333885 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.052195223119721 bayes_pls_golite062009
cation transmembrane transporter activity 0.0405268469927988 bayes_pls_golite062009
transcription activator activity 0.0232727461674547 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [703-916]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HDQEFDDKFV ELVPFLKYGI ETHTEILPTL LEIIKSYALI LNPVDFFSNN TFQDIFKQMS  60
   61 KYLLKLREDS FQLVLEIWEI LILSNESDYE NLLLQKFYET GVLSALFDAI FLEEAPSSYL 120
  121 CSQIIQIIAR ISYVNPDALM TFLATYHDNL PTSNENARMP ESIRKIVSKD QTYDSVVNKL 180
  181 LTGWIVCFRD IFDPKFKKVH ILGISSLLRT GLVP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [917-1032]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILTEFSSIAS LWIEMLEEIN ETNRGDCEKY HLNDIVTEQS IAFHPLTAEQ LRYHQLCKNN  60
   61 DPVHNISLKD FISQSMEYLE SHLGVERYQE FLKTINPSLL ENLQMFLSIQ PQEARP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle