YRC Public Data Repository - Protein Structure Prediction

Protein:	SNX3
Organism:	Saccharomyces cerevisiae
Length:	162 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SNX3.

Description	E-value	Query Range	Subject Range
SNX3 - Sorting nexin required to maintain late-Golgi resident enzymes in their proper location by recycling... gi\|151945434 - gi\|151945434\|gb\|EDN63677.1\| sorting nexin [Saccharomyces cerevisiae YJM789] gi\|207340829 - gi\|207340829\|gb\|EDZ69059.1\| YOR357Cp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190407650 - gi\|190407650\|gb\|EDV10917.1\| sorting nexin GRD19 [Saccharomyces cerevisiae RM11-1a] SNX3_YEAST - Sorting nexin-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SNX3 PE=1 SV=1	1.0E-38	[1..162]	[1..162]
SNX3_MOUSE - Sorting nexin-3 OS=Mus musculus GN=Snx3 PE=1 SV=3	1.0E-31	[8..158]	[4..148]
gi\|60653701, gi\|... - gi\|60653703\|gb\|AAX29545.1\| sorting nexin 3 [synthetic construct], gi\|60653701\|gb\|AAX29544.1\| sorting...	2.0E-31	[8..158]	[4..148]
gi\|114608755, gi... - gi\|55627184\|ref\|XP_518671.1\| PREDICTED: sorting nexin 3 isoform 5 [Pan troglodytes], gi\|114608755\|re... gi\|190402237 - gi\|190402237\|gb\|ACE77651.1\| sorting nexin 3 (predicted) [Sorex araneus] gi\|12850385, gi\|... - gi\|74208380\|dbj\|BAE26381.1\| unnamed protein product [Mus musculus], gi\|74185844\|dbj\|BAE32792.1\| unna... gi\|197215628 - gi\|197215628\|gb\|ACH53022.1\| sorting nexin 3 (predicted) [Otolemur garnettii] gi\|164449657 - gi\|164449657\|gb\|ABY56295.1\| sorting nexin 3 (predicted) [Papio anubis] SNX3 - sorting nexin 3 gi\|61361693, gi\|... - gi\|61361693\|gb\|AAX42088.1\| sorting nexin 3 [synthetic construct], gi\|190691283\|gb\|ACE87416.1\| sortin... gi\|226526922 - gi\|226526922\|gb\|ACO71280.1\| sorting nexin 3 (predicted) [Dasypus novemcinctus] gi\|166183799 - gi\|166183799\|gb\|ABY84161.1\| sorting nexin 3 (predicted) [Callithrix jacchus] gi\|149722861 - gi\|149722861\|ref\|XP_001504033.1\| PREDICTED: similar to Sorting nexin-3 (Protein SDP3) [Equus caballu... SNX3_BOVIN - Sorting nexin-3 OS=Bos taurus GN=SNX3 PE=2 SV=3 SNX3_PONAB - Sorting nexin-3 OS=Pongo abelii GN=SNX3 PE=2 SV=3 gi\|109073121, gi... - gi\|109073121\|ref\|XP_001094537.1\| PREDICTED: sorting nexin 3 isoform 4 [Macaca mulatta], gi\|109073119... gi\|169409579 - gi\|169409579\|gb\|ACA57921.1\| sorting nexin 3 (predicted) [Callicebus moloch] gi\|183637195 - gi\|183637195\|gb\|ACC64553.1\| sorting nexin 3 (predicted) [Rhinolophus ferrumequinum] SNX3_PONPY - Sorting nexin-3 - Pongo pygmaeus (Orangutan) gi\|217038307 - gi\|217038307\|gb\|ACJ76604.1\| sorting nexin 3 (predicted) [Oryctolagus cuniculus] gi\|55250822 - gb\|AAH86258.1\| Unknown (protein for MGC:98781) [Xenopus laevis] SNX3_RAT - Sorting nexin-3 OS=Rattus norvegicus GN=Snx3 PE=1 SV=1	2.0E-31	[8..158]	[4..148]
gi\|195329484, gi... - gi\|195329484\|ref\|XP_002031441.1\| GM24045 [Drosophila sechellia], gi\|194120384\|gb\|EDW42427.1\| GM24045... gi\|194183518, gi... - gi\|195500545\|ref\|XP_002097417.1\| GE26205 [Drosophila yakuba], gi\|194183518\|gb\|EDW97129.1\| GE26205 [D... gi\|195571379, gi... - gi\|195571379\|ref\|XP_002103681.1\| GD18845 [Drosophila simulans], gi\|194199608\|gb\|EDX13184.1\| GD18845 ... gi\|220948892, gi... - gi\|220957720\|gb\|ACL91403.1\| CG6359-PA [synthetic construct], gi\|220948892\|gb\|ACL86989.1\| CG6359-PA [... CG6359-PA, FBpp0... - This gene is referred to in FlyBase by the symbol Dmel\CG6359 (CG6359, FBgn0038065). It is a protein... gi\|125773063\|ref... - GA19538-PA [Drosophila pseudoobscura], GA19538 [Drosophila pseudoobscura pseudoobscura] gi\|125773063, gi... - gi\|54637523\|gb\|EAL26925.1\| GA19538 [Drosophila pseudoobscura pseudoobscura], gi\|125773063\|ref\|XP_001... gi\|194742369, gi... - gi\|194742369\|ref\|XP_001953675.1\| GF17109 [Drosophila ananassae], gi\|190626712\|gb\|EDV42236.1\| GF17109... gi\|194901676, gi... - gi\|194901676\|ref\|XP_001980378.1\| GG19071 [Drosophila erecta], gi\|190652081\|gb\|EDV49336.1\| GG19071 [D... gi\|195158897, gi... - gi\|195158897\|ref\|XP_002020320.1\| GL13919 [Drosophila persimilis], gi\|194117089\|gb\|EDW39132.1\| GL1391...	1.0E-30	[1..158]	[1..153]
gi\|21538835 - gi\|21538835\|gb\|AAM61764.1\|AF461063_3 sorting nexin 3 [Takifugu rubripes]	2.0E-30	[6..156]	[2..146]
gi\|147898463, gi... - gi\|27696428\|gb\|AAH43969.1\| MGC53351 protein [Xenopus laevis], gi\|147898463\|ref\|NP_001079514.1\| hypot...	8.0E-29	[5..158]	[2..149]

Back

Predicted Domain #1

Region A:
Residues: [1-162]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPREFKSFGS TEKSLLSKGH GEPSYSEIYA EPENFLEIEV HNPKTHIPNG MDSKGMFTDY  60
   61 EIICRTNLPS FHKRVSKVRR RYSDFEFFRK CLIKEISMLN HPKVMVPHLP GKILLSNRFS 120
  121 NEVIEERRQG LNTWMQSVAG HPLLQSGSKV LVRFIEAEKF VG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.522879
Match:	1h6hA_
Description:	p40phox NADPH oxidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.88408675542289	bayes_pls_golite062009
protein binding	2.01416287650553	bayes_pls_golite062009
phosphoinositide binding	1.69611539954228	bayes_pls_golite062009
phospholipid binding	1.3509978234193	bayes_pls_golite062009
lipid binding	0.663652920263169	bayes_pls_golite062009
phosphatidylinositol-3-phosphate binding	0.643843925142106	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: