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View Structure Prediction Details

Protein: PLP2
Organism: Saccharomyces cerevisiae
Length: 286 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PLP2.

Description E-value Query
Range
Subject
Range
PLP2 - Essential protein that interacts with the CCT (chaperonin containing TCP-1) complex to stimulate act...
PLP2_YEAST - Phosducin-like protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PLP2 PE=1 SV=1
4.0E-53 [1..286] [1..286]
PDCL3 - phosducin-like 3
2.0E-52 [12..240] [3..218]
gi|12835481 - gi|12835481|dbj|BAB23267.1| unnamed protein product [Mus musculus]
6.0E-52 [12..241] [3..219]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-46 [11..243] [1..236]
SPBC2A9.09 - phosducin family protein
YGI9_SCHPO - Phosducin-like protein C2A9.09 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC2A9.09 ...
9.0E-44 [11..243] [1..215]
gi|7573449, gi|1... - gi|7573449|emb|CAB87763.1| putative protein [Arabidopsis thaliana], gi|24030416|gb|AAN41366.1| unkno...
2.0E-40 [13..280] [12..256]
gi|9558421, gi|3... - gi|9558421|dbj|BAB03357.1| putative phosducin-like 3 [Oryza sativa Japonica Group], gi|34906294|ref|...
1.0E-39 [13..269] [12..237]

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Predicted Domain #1
Region A:
Residues: [1-237]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNEPMFQVQ VDESEDSEWN DILRAKGVIP ERAPSPTAKL EEALEEAIAK QHENRLEDKD  60
   61 LSDLEELEDD EDEDFLEAYK IKRLNEIRKL QERSKFGEVF HINKPEYNKE VTLASQGKKY 120
  121 EGAQTNDNGE EDDGGVYVFV HLSLQSKLQS RILSHLFQSA ACKFREIKFV EIPANRAIEN 180
  181 YPESNCPTLI VYYRGEVIKN MITLLELGGN NSKMEDFEDF MVKVGAVAEG DNRLIMN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.27013
Match: 1a0rP_
Description: Phosducin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein disulfide isomerase activity 2.22938352402713 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds 2.22938352402713 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups 2.0668189994058 bayes_pls_golite062009
antioxidant activity 1.38472228155226 bayes_pls_golite062009
transcription regulator activity 1.26775679034218 bayes_pls_golite062009
protein binding 1.18479617596618 bayes_pls_golite062009
peroxidase activity 1.15636364216535 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 1.15636364216535 bayes_pls_golite062009
disulfide oxidoreductase activity 0.893289664404565 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
binding 0.618139748326926 bayes_pls_golite062009
peroxiredoxin activity 0.366096607480921 bayes_pls_golite062009
glutathione peroxidase activity 0.360252986649711 bayes_pls_golite062009
transcription activator activity 0.322947914353705 bayes_pls_golite062009
protein disulfide oxidoreductase activity 0.27885589181966 bayes_pls_golite062009
thioredoxin peroxidase activity 0.163136748643487 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [238-286]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDDEESREER KLHYGEKKSI RSGIRGKFNV GIGGNDDGNI NDDDDGFFD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.045757
Match: 1bjx__
Description: Protein disulfide isomerase, PDI
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle