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View Structure Prediction Details

Protein: PAC1
Organism: Saccharomyces cerevisiae
Length: 494 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PAC1.

Description E-value Query
Range
Subject
Range
gi|17225208 - gi|17225208|gb|AAL37300.1|AF323584_1 beta transducin-like protein HET-E2C*40 [Podospora anserina]
0.0 [33..492] [832..1246]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [3..492] [999..1479]

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Predicted Domain #1
Region A:
Residues: [1-153]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNWQQQLPL TDTQKNELDK SVLRYLNWNY KQTVRHEHAQ DYESVRHAIV TLSGFLLQES  60
   61 VDRQEFISNN DTSNESMVDI DELLLPKKWN SIVRLQKKII ELEQNTETLV SQIKDLNTQV 120
  121 SELAQFKPTT SNGTSAHNVL KWIPRNLPSC LIN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.522879
Match: 1gxrA_
Description: Groucho/tle1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [154-494]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VESSVTSVKL HPNLPIVFVA TDHGKLYAFD LFNYTIPLAS LQSHTKAITS MDVLFTNYTN  60
   61 SSKKNYLVIV TASKDLQIHV FKWVSEECKF QQIRSLLGHE HIVSAVKIWQ KNNDVHIASC 120
  121 SRDQTVKIWD FHNGWSLKTF QPHSQWVRSI DVLGDYIISG SHDTTLRLTH WPSGNGLSVG 180
  181 TGHEFPIEKV KFIHFIEDSP EIRFRTPSTD RYKNWGMQYC VSASRDRTIK IWEIPLPTLM 240
  241 AHRAPIPNPT DSNFRCVLTL KGHLSWVRDI SIRGQYLFSC ADDKSVRCWD LNTGQCLHVW 300
  301 EKLHTGFVNC LDLDVDFDSN VTPRQMMVTG GLDCKSNVFM R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 127.39794
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
dynactin binding 7.11157019623125 bayes_pls_golite062009
dynein heavy chain binding 6.59987903164261 bayes_pls_golite062009
histone methyltransferase activity (H3-K4 specific) 4.71992275913384 bayes_pls_golite062009
actin binding 3.86142918698875 bayes_pls_golite062009
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
tubulin binding 2.76945430061825 bayes_pls_golite062009
microtubule binding 2.72684103222924 bayes_pls_golite062009
dynein binding 2.54821997913979 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
snoRNA binding 2.20077763915561 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 2.18628561734369 bayes_pls_golite062009
actin filament binding 2.0735069176589 bayes_pls_golite062009
histone methyltransferase activity 1.85632145559025 bayes_pls_golite062009
transporter activity 1.65168247201205 bayes_pls_golite062009
nucleic acid binding 1.40004045504145 bayes_pls_golite062009
platelet-activating factor acetyltransferase activity 1.36229564654648 bayes_pls_golite062009
protein methyltransferase activity 1.35170368882651 bayes_pls_golite062009
transcription regulator activity 1.25687092973217 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.22384651674093 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
microtubule plus-end binding 1.01166033978052 bayes_pls_golite062009
myosin binding 0.989691178611801 bayes_pls_golite062009
protein transporter activity 0.964340340346761 bayes_pls_golite062009
0.88172763425403 bayes_pls_golite062009
myosin heavy chain kinase activity 0.848140419140051 bayes_pls_golite062009
DNA binding 0.711274653406079 bayes_pls_golite062009
dynein intermediate chain binding 0.707581908546932 bayes_pls_golite062009
histone binding 0.685319917508843 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.426429095658617 bayes_pls_golite062009
kinase activity 0.387572734234845 bayes_pls_golite062009
molecular transducer activity 0.367729389382533 bayes_pls_golite062009
signal transducer activity 0.367729389382533 bayes_pls_golite062009
structural molecule activity 0.254012051644049 bayes_pls_golite062009
transcription factor activity 0.243992994917491 bayes_pls_golite062009
protein kinase activity 0.229242350006544 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.226335610368636 bayes_pls_golite062009
ligase activity 0.20682813699621 bayes_pls_golite062009
enzyme regulator activity 0.161639372576406 bayes_pls_golite062009
chromatin binding 0.145491963066342 bayes_pls_golite062009
substrate-specific transporter activity 0.121183207943714 bayes_pls_golite062009
myosin II binding 0.12060669039328 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
RNA binding 0.0914092269020899 bayes_pls_golite062009
transcription repressor activity 0.084112683169759 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009
N-methyltransferase activity 0.00335766408304172 bayes_pls_golite062009

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