| Protein: | TRE2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 809 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRE2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..809] | [1..809] |
|
|
0.0 | [124..803] | [17..750] |
|
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0.0 | [124..802] | [17..751] |
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0.0 | [124..803] | [17..751] |
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0.0 | [124..803] | [17..752] |
|
|
0.0 | [159..778] | [135..764] |
|
Region A: Residues: [1-151] |
1 11 21 31 41 51
| | | | | |
1 MRSSYQPVST TNFEHENAIP TASSSHNLLM SQRFDDSPPS SNDNSIETNI TPPPEPPSYE 60
61 FDIEDPHDDL HKRTHLQRVS IGFQEKILEP LMENIIHPLL QISKFVPDKA DYYLSKIGNP 120
121 FILRRFFYII FMSFIAYYVL SSGYLFNEKA S
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.436 | a.1.1 | Globin-like |
| View | Download | 0.310 | a.1.1 | Globin-like |
| View | Download | 0.282 | a.1.1 | Globin-like |
| View | Download | 0.273 | a.1.1 | Globin-like |
| View | Download | 0.254 | a.1.1 | Globin-like |
|
Region A: Residues: [152-224] |
1 11 21 31 41 51
| | | | | |
1 GSKGMFSQHD ILFEYAKKSV DLAKFERDLE YISSMPHGSG TKGDAAIYRY IQESFDNNGL 60
61 KLVKEMGYSV YSN
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|
Region B: Residues: [338-363] |
1 11 21 31 41 51
| | | | | |
1 QYSTGDASGL NWDGSPVEEK DHKFWR
|
|
Region C: Residues: [418-636] |
1 11 21 31 41 51
| | | | | |
1 REKHFIPNIV GKIEGREQSD KAIIIAASRN SINFGTTYPN FGTAALLSIV QLFQEVKYKF 60
61 GWKPLRNIYF ISFGGTEFNY AGSSELVEQR LTPLKDEIYS LIDISQLGIP FAEKYENGKT 120
121 RGELSIETHP LLKKFFNRNA HGNFDISVDN VQHYGDWTPF LANGIPVSVI SSDSTRNRDT 180
181 PTETSEDKFE RVEKILEDEQ NQQSVKDLLV YLLHISMEL
|
| Detection Method: | |
| Confidence: | 243.0103 |
| Match: | 1de4C_ |
| Description: | Transferrin receptor ectodomain, C-terminal domain; Transferrin receptor ectodomain, apical domain; Transferrin receptor ectodomain, protease-like domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 3.64510404037841 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 3.26499474130077 | bayes_pls_golite062009 |
| hydrolase activity | 2.98013991489506 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.66431152897721 | bayes_pls_golite062009 |
| receptor activity | 2.50668975998057 | bayes_pls_golite062009 |
| molecular transducer activity | 2.43554678928141 | bayes_pls_golite062009 |
| signal transducer activity | 2.43554678928141 | bayes_pls_golite062009 |
| metallopeptidase activity | 2.04062448553328 | bayes_pls_golite062009 |
| exopeptidase activity | 1.5759162922092 | bayes_pls_golite062009 |
| catalytic activity | 1.3989281287879 | bayes_pls_golite062009 |
| binding | 1.13031326446259 | bayes_pls_golite062009 |
| transferrin receptor activity | 1.08060244646522 | bayes_pls_golite062009 |
| carboxypeptidase activity | 0.891655769761122 | bayes_pls_golite062009 |
| metalloexopeptidase activity | 0.472688733072762 | bayes_pls_golite062009 |
| nucleic acid binding | 0.454707207494165 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 0.204452912688153 | bayes_pls_golite062009 |
| metallocarboxypeptidase activity | 0.180859448845431 | bayes_pls_golite062009 |
| transcription regulator activity | 0.175639750716837 | bayes_pls_golite062009 |
| DNA binding | 0.115087846898245 | bayes_pls_golite062009 |
| aminopeptidase activity | 0.0966237570696103 | bayes_pls_golite062009 |
|
Region A: Residues: [225-337] |
1 11 21 31 41 51
| | | | | |
1 YPGNVSISYY DNKNEKHDLE LSKENFNPLS SNGKLSKVSL IYGGKGTTYD LQHLKDSKTI 60
61 EDGKDYVLLL QYDKLVSQQV LIAEKFGAKA VIFISEPYGE NIDVVQSKPV GLP
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|
Region B: Residues: [364-417] |
1 11 21 31 41 51
| | | | | |
1 QTHIPTIPIS TRQGKELLSR LSSGGVTVDD GNSDRSNSGK MGDVLIDVDL QTNV
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|
Region C: Residues: [637-809] |
1 11 21 31 41 51
| | | | | |
1 IDDPLLHFDI ISYVEDIDER LQRLEQAYPE KLNFTSIIKG LLFWKKIGSE WASWTQGWEN 60
61 IVWSHGDGIE PSLLSINRWT WNKKLTNIGR RTCSPAGLPN RSFYKNVLFG PTLIQEDKSK 120
121 NGGNVDFWTF PGVMDAIYDD DWKRAQEQID LIGKVLHQSA ALFVEETNDI GYK
|
| Detection Method: | |
| Confidence: | 243.0103 |
| Match: | 1de4C_ |
| Description: | Transferrin receptor ectodomain, C-terminal domain; Transferrin receptor ectodomain, apical domain; Transferrin receptor ectodomain, protease-like domain |
| Matching Structure (courtesy of the PDB): |
|
