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View Structure Prediction Details

Protein: SPR1
Organism: Saccharomyces cerevisiae
Length: 445 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPR1.

Description E-value Query
Range
Subject
Range
SPR1_YEAST - Sporulation-specific glucan 1,3-beta-glucosidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S...
SPR1 - Sporulation-specific exo-1,3-beta-glucanase; contributes to ascospore thermoresistance
0.0 [1..445] [1..445]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [2..444] [6..435]
EXG_CANAL - Glucan 1,3-beta-glucosidase OS=Candida albicans GN=XOG1 PE=1 SV=3
0.0 [2..444] [6..435]
EXG_KLULA - Glucan 1,3-beta-glucosidase OS=Kluyveromyces lactis GN=KLLA0C05324g PE=3 SV=1
EXG_KLULA - Glucan 1,3-beta-glucosidase OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC ...
0.0 [1..444] [1..425]
EXG2_WICAO - Glucan 1,3-beta-glucosidase 2 OS=Wickerhamomyces anomalus GN=EXG2 PE=3 SV=1
2.0E-98 [9..444] [6..426]
EXG_SCHOC - Glucan 1,3-beta-glucosidase OS=Schwanniomyces occidentalis PE=3 SV=1
4.0E-95 [2..444] [1..423]

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Predicted Domain #1
Region A:
Residues: [1-297]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSFRGLTTL TLLFTKLVNC NPVSTKNRDS IQFIYKEKDS IYSAINNQAI NEKIHGVNLG  60
   61 GWLVLEPYIT PSLFETFRTN PYNDDGIPVD EYHFCEKLGY EKAKERLYSH WSTFYKEEDF 120
  121 AKIASQGFNL VRIPIGYWAF TTLSHDPYVT AEQEYFLDRA IDWARKYGLK VWIDLHGAAG 180
  181 SQNGFDNSGL RDSYKFLEDE NLSATMKALT YILSKYSTDV YLDTVIGIEL LNEPLGPVID 240
  241 MERLKNLLLK PAYDYLRNKI NSNQIIVIHD AFQPYHYWDG FLNDEKNEYG VIIDHHH

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [320-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WGKDAVSEKH WSVAGEF

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [400-414]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AFEMTGGWIM WCYKT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1328.69897
Match: 1cz1A_
Description: Exo-beta-(1,3)-glucanase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, acting on glycosyl bonds 5.36248919165223 bayes_pls_golite062009
glucan 1,3-beta-glucosidase activity 5.16200085143699 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 4.11319792356479 bayes_pls_golite062009
glucosidase activity 3.69195576225095 bayes_pls_golite062009
beta-glucosidase activity 3.14931331494576 bayes_pls_golite062009
chitinase activity 2.45357334610104 bayes_pls_golite062009
alpha-amylase activity 2.09193270404736 bayes_pls_golite062009
amylase activity 2.03484942782894 bayes_pls_golite062009
catalytic activity 1.85569074294201 bayes_pls_golite062009
hydrolase activity 1.22608062881808 bayes_pls_golite062009
binding 1.08189849662259 bayes_pls_golite062009
hexosaminidase activity 0.763360027922833 bayes_pls_golite062009
carbohydrate binding 0.4998423581103 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.266938437560648 bayes_pls_golite062009
beta-N-acetylhexosaminidase activity 0.263065978664289 bayes_pls_golite062009
hyalurononglucosaminidase activity 0.123700697143861 bayes_pls_golite062009
receptor binding 0.0577582382963624 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [298-319]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YQVFSQVELT RKMNERIKIA CQ

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [337-399]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAALTDCTKW LNGVGLGARY DGSWTKDNEK SHYINTCANN ENIALWPEER KQNTRKFIEA  60
   61 QLD

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [415-445]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENSIEWDVEK LIQLNIFPQP INDRKYPNQC H

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1328.69897
Match: 1cz1A_
Description: Exo-beta-(1,3)-glucanase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle