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View Structure Prediction Details

Protein: MTR10
Organism: Saccharomyces cerevisiae
Length: 972 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTR10.

Description E-value Query
Range
Subject
Range
MTR10 - Nuclear import receptor, mediates the nuclear localization of proteins involved in mRNA-nucleus expo...
MTR10_YEAST - mRNA transport regulator MTR10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MTR10 PE=...
0.0 [1..972] [1..972]
XPO1 - exportin 1 (CRM1 homolog, yeast)
gi|109103010, gi... - gi|109103012|ref|XP_001115623.1| PREDICTED: similar to exportin 1 isoform 3 [Macaca mulatta], gi|109...
gi|208967809, gi... - gi|208967809|dbj|BAG72550.1| exportin 1 [synthetic construct], gi|123980736|gb|ABM82197.1| exportin ...
0.0 [4..958] [23..1018]
gi|5690335 - gi|5690335|gb|AAD47043.1|AF158021_1 CRM1/XPO1 protein [Xenopus laevis]
0.0 [4..958] [23..1018]
gi|14250864 - gi|14250864|emb|CAC39223.1| exportin 1b [Arabidopsis thaliana]
0.0 [5..958] [14..1026]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [3..958] [10..1023]
gi|11493965 - gi|11493965|gb|AAG35722.1| crm1 protein [Schizosaccharomyces pombe]
0.0 [3..958] [10..1024]
gi|5734611 - gi|5734611|dbj|BAA83347.1| Crm1-K1 [synthetic construct]
0.0 [3..958] [10..1024]

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Predicted Domain #1
Region A:
Residues: [1-642]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNLQVSDIE TALQCISSTA SQDDKNKALQ FLEQFQRSTV AWSICNEILS KEDPTNALLE  60
   61 LNIFAAQTLR NKVTYDLSQL ENNLPQFKDS LLTLLLSHNQ KLIITQLNVA LARLAIQFLE 120
  121 WQNPIFEIIS LLNSSPSILL NFLRILPEET LDIASTSLTE VEFNSRIHEL IDPIAEDVLK 180
  181 FLVSCIDLLQ NTDGNSSSSI SLEQILRCLN SWSYEFPVEQ LLTVQPLINL VFETISNGNE 240
  241 SDMEAFDSAI DCLCVILRES RDTTNEQLIS ALFHQLMLLQ EKLLPTLFTD HPLNDEYDDD 300
  301 LLEGMTRLFV EAGEAWSVVI SKNPDFFKPM VLVLLMLTCK NEDLDVVSYT FPFWFNFKQS 360
  361 LVLPRYQESR KAYSDIFVKL INGIITHLQY PSGQFSSKEE EDKFKDFRYH MGDVLKDCTA 420
  421 VVGTSEALSQ PLIRIKSAIE NNNSWQIMEA PLFSLRTMAK EISLTENTIL PEIIKIICNL 480
  481 PEQAKIRYAS TLVLGRYTEW TAKHPELLEV QLQYIFNGFQ LHEGSSDMQS IITASSHALM 540
  541 FFCSDCSKLL VGYIDQLINF FLNVQSSIDI ESQFELCQGL SAVINNQPEA KVSVIFQKLV 600
  601 DDNLRQIEAL IPQWKANPTL LAPQIADKID LLYALFEELK PR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [643-972]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YNYPQQGSEP LLPRIEFIWK ALRTLLVDAG AMTDSIIVER VAKLLRRIFE RFHVFCEPIL  60
   61 PSVAEFLIQG YLTTGFGSYL WCSGSLIVIF GDDESFPISP SLKDAVWKFA LSQCETFILN 120
  121 FNKFDKLQLN DYHEAIIDFF SLISDLIMFY PGAFLNSTEL LGPVLNVALE CVNKLDNYDA 180
  181 YICILRCLDD IISWGFKTPP ISTVSIEIVP DEWRKQVINE VVIAHGNQLI LVLFIGLVTT 240
  241 FENTAHSDAI SCIVKCLRIL TEANNNDATI CIDWIYKVVE QLGQVTLNER DNLAKAVVEG 300
  301 LNSKDYRKVR EGIRAFVGWY SRKNINSRFE 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
protein transporter activity 4.58709163830613 bayes_pls_golite062009
binding 3.0667965351474 bayes_pls_golite062009
transporter activity 2.92319684675174 bayes_pls_golite062009
nucleic acid binding 2.74745843355294 bayes_pls_golite062009
protein transmembrane transporter activity 2.74547353635661 bayes_pls_golite062009
RNA binding 2.62683106046883 bayes_pls_golite062009
nuclear export signal receptor activity 2.13470398426489 bayes_pls_golite062009
nuclear localization sequence binding 1.91487015967262 bayes_pls_golite062009
transcription regulator activity 1.90912542848632 bayes_pls_golite062009
DNA binding 1.77040152722002 bayes_pls_golite062009
protein binding 1.73688475473996 bayes_pls_golite062009
substrate-specific transporter activity 1.65364344577652 bayes_pls_golite062009
transmembrane transporter activity 1.6217303285315 bayes_pls_golite062009
transcription factor activity 1.27944481949335 bayes_pls_golite062009
mRNA binding 1.24616647164637 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.20870827474803 bayes_pls_golite062009
structural molecule activity 0.908029258648777 bayes_pls_golite062009
RNA cap binding 0.85485270555676 bayes_pls_golite062009
translation initiation factor activity 0.83079633551839 bayes_pls_golite062009
translation regulator activity 0.82193201542158 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.803700928110921 bayes_pls_golite062009
signal sequence binding 0.57106697498903 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.100181463251306 bayes_pls_golite062009
transcription activator activity 0.0797305392056347 bayes_pls_golite062009
pyrophosphatase activity 0.0635404099346928 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0548082069333885 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.052195223119721 bayes_pls_golite062009
transcription factor binding 0.00210118982863072 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle