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View Structure Prediction Details

Protein: ENB1
Organism: Saccharomyces cerevisiae
Length: 606 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ENB1.

Description E-value Query
Range
Subject
Range
ENB1_YEAST - Siderophore iron transporter ENB1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ENB1 P...
ENB1 - Endosomal ferric enterobactin transporter, expressed under conditions of iron deprivation; member of...
2.0E-91 [1..606] [1..606]
gi|19386936 - gi|19386936|gb|AAL87047.1|AF448056_3 putative dothistromin transporter [Mycosphaerella pini]
gi|19386936 - gi|19386936|gb|AAL87047.1|AF448056_3 putative dothistromin transporter [Mycosphaerella pini]
1.0E-89 [2..602] [1..594]
gi|21225257, gi|... - gi|7649556|emb|CAB89031.1| putative membrane transport protein. [Streptomyces coelicolor A3(2)], gi|...
6.0E-85 [40..579] [5..522]
gi|16944692 - gi|16944692|emb|CAC28808.2| related to tetracycline efflux protein (otrb) [Neurospora crassa]
9.0E-84 [22..597] [2..577]
gi|15528453 - gi|15528453|emb|CAC69145.1| putative membrane protein [Pichia anomala]
1.0E-80 [7..603] [37..619]
gi|14389419 - gi|14389419|gb|AAF64435.2|AF238225_1 DHA14-like major facilitator [Botryotinia fuckeliana]
1.0E-80 [2..582] [37..594]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-79 [34..576] [9..530]
SPBC16A3.17c - membrane transporter
YBIH_SCHPO - Uncharacterized MFS-type transporter C16A3.17c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843...
2.0E-77 [9..603] [44..599]

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Predicted Domain #1
Region A:
Residues: [1-256]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLETDHSRND NLDDKSTVCY SEKTDSNVEK STTSGLRRID AVNKVLSDYS SFTAFGVTFS  60
   61 SLKTALLVAL FLQGYCTGLG GQISQSIQTY AANSFGKHSQ VGSINTVKSI VASVVAVPYA 120
  121 RISDRFGRIE CWIFALVLYT IGEIISAATP TFSGLFAGIV IQQFGYSGFR LLATALTGDL 180
  181 SGLRDRTFAM NIFLIPVIIN TWVSGNIVSS VAGNVAPYKW RWGYGIFCII VPISTLILVL 240
  241 PYVYAQYISW RSGKLP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1lviA_
Description: No description for 1lviA_ was found.

Predicted functions:

Term Confidence Notes
substrate-specific transmembrane transporter activity 5.46247398538901 bayes_pls_golite062009
ion transmembrane transporter activity 4.58978526526921 bayes_pls_golite062009
cation transmembrane transporter activity 4.31967711223954 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
binding 1.26757615356623 bayes_pls_golite062009
anion transmembrane transporter activity 1.24023641504332 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [257-325]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLKLKEKGQT LRQTLWKFAD DINLIGVILF TAFLVLVLLP LTIAGGATSK WREGHIIAMI  60
   61 VVGGCLGFI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [326-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLIWELKFAK NPFIPRVYLG DPTIYVALLM EFVWRLGLQI ELEYLVTVLM VAFGESTLSA  60
   61 QRIAQLYNFL QSCTNIVVGI MLHFYPHPKV FVVAGSLLGV IGMGLLYKYR VVYDGISGLI 120
  121 GAEIVVGIAG GMIRFPMWTL VHASTTHNEM ATVTGLLMSV YQIGDAVGAS IAGAIWTQRL 180
  181 AKELIQRLGS SLGMAIYKSP LNYLKKYP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [534-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGSEVRVQMI ESYSKIQRLL IIVSISFAAF NAVLCFFLRG FTVNKKQSLS AEEREKEKLK  60
   61 IKQQSWLRRV IGY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle