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View Structure Prediction Details

Protein: GAS4
Organism: Saccharomyces cerevisiae
Length: 471 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GAS4.

Description E-value Query
Range
Subject
Range
GAS4 - 1,3-beta-glucanosyltransferase, involved with Gas2p in spore wall assembly; has similarity to Gas1p;...
gi|151945503 - gi|151945503|gb|EDN63744.1| conserved protein [Saccharomyces cerevisiae YJM789]
GAS4_YEAST - 1,3-beta-glucanosyltransferase GAS4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GAS4...
0.0 [1..452] [1..452]
gi|6911253 - gi|6911253|gb|AAF31451.1|AF221545_1 PHR3p [Candida albicans]
0.0 [9..435] [5..445]
gi|18073449 - gi|18073449|emb|CAC83344.1| GAS-1 homologue [Candida glabrata]
0.0 [2..377] [1..370]
EPD1_CANMA - Protein EPD1 OS=Candida maltosa GN=EPD1 PE=3 SV=1
0.0 [2..377] [1..370]
gi|10441337 - gi|10441337|gb|AAG16996.1|AF184908_1 pH-regulated protein 2 [Candida dubliniensis]
gi|241947959, gi... - gi|241947959|ref|XP_002416702.1| pH-regulated protein 2 [Candida dubliniensis CD36], gi|223640040|em...
0.0 [2..377] [1..370]
GEL2_ASPFC - 1,3-beta-glucanosyltransferase gel2 OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)...
GEL2_ASPFU - 1,3-beta-glucanosyltransferase gel2 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 1013...
GEL2_ASPFU - 1,3-beta-glucanosyltransferase gel2 OS=Aspergillus fumigatus GN=gel2 PE=3 SV=1
0.0 [7..413] [4..413]

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Predicted Domain #1
Region A:
Residues: [1-343]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMVFSSTFIF LILELVVLCE ASVHTIQIKD KHFVDTVTGK PFFIKGVDYQ PGGSSDVSEK  60
   61 QDPLSNPDAC ARDILLFQEL GINTVRIYSI NPDLNHDACM TMLAMAGIYL ILDVNSPLQN 120
  121 QHLNRYEPWT TYNEVYLEHV FKVVEQFSHY NNTLGFFAGN EIVNDKRSAQ YSPAYVKELI 180
  181 GTMKNYISAH SPRTIPVGYS AADDLNYRVS LSEYLECKDD DKPENSVDFY GVNSYQWCGQ 240
  241 QTMQTSGYDT LVDAYRSYSK PVFFSEFGCN KVLPRQFQEI GYLFSEEMYS VFCGGLVYEF 300
  301 SQEDNNYGLV EYQEDDSVQL LADFEKLKSH YQNIEFPSMK TLK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 229.920819
Match: PF03198
Description: Glycolipid anchored surface protein (GAS1)

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
glucan 1,3-beta-glucosidase activity 4.74305379082042 bayes_pls_golite062009
beta-glucosidase activity 4.08728799854386 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 3.82308281904462 bayes_pls_golite062009
glucosidase activity 3.42748790579187 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 2.21061553009372 bayes_pls_golite062009
hydrolase activity 1.33241439716102 bayes_pls_golite062009
binding 0.519762370064533 bayes_pls_golite062009
alpha-amylase activity 0.318549118740213 bayes_pls_golite062009
fucose binding 0.289279546872586 bayes_pls_golite062009
hexosaminidase activity 0.152927193173404 bayes_pls_golite062009
chitinase activity 0.139132768318145 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [344-471]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETVQMEETPS CAEDYENLKI ESKIAKNLGS SLIKKGVKVE KGKYIDIHED QLSTNVTILD  60
   61 KHGDRWNGPK KIEIRQSLTL ADLEGEEQED ADEDKDDLKR KHRNSASISG PLLPLGLCLL 120
  121 FFTFSLFF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.510 d.110.4 SNARE-like
View Download 0.454 a.29.2 Bromodomain
View Download 0.353 a.40.1 Calponin-homology domain, CH-domain
View Download 0.340 a.7.7 BAG domain
View Download 0.319 d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.309 d.129.4 Cell-division protein ZipA, C-terminal domain
View Download 0.297 d.87.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
View Download 0.282 a.26.1 4-helical cytokines
View Download 0.273 a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.235 d.224.1 SufE-like
View Download 0.216 a.25.1 Ferritin-like
View Download 0.204 d.52.4 YhbC-like, N-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle