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View Structure Prediction Details

Protein: PHM7
Organism: Saccharomyces cerevisiae
Length: 991 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PHM7.

Description E-value Query
Range
Subject
Range
PHM7 - Protein of unknown function, expression is regulated by phosphate levels; green fluorescent protein ...
PHM7_YEAST - Phosphate metabolism protein 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PHM7 PE=1...
0.0 [1..991] [1..991]
CSCL6_ARATH - CSC1-like protein At1g62320 OS=Arabidopsis thaliana GN=At1g62320 PE=3 SV=2
0.0 [8..792] [5..765]

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Predicted Domain #1
Region A:
Residues: [1-193]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADSSSTSAF ISTLIIYGLT AVVFVWLFLL LRPKNRRVYE PRSLKDIQTI PEEERTEPVP  60
   61 EGYFGWVEYL LSKPHSFLIQ HTSVDGYFLL RYIGIVGSLS FVGCLLLLPI LLPVNATNGN 120
  121 NLQGFELLSF SNVTNKNRFY AHVFLSWIFF GLFTYVIYKE LYYYVVFRHA MQTTPLYDGL 180
  181 LSSRTVIVTE LHK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [194-292]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIAQEGEMQM RFPKASNVAF AYDLSDLQEL CKERAKNAAK YEAALNKVLN KCVKMTRNKT  60
   61 QKQLDKLYNN GTKPKDDLET YVPHKKRPKH RLGKLPLCL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.722 a.7.1 Spectrin repeat
View Download 0.420 a.47.2 t-snare proteins
View Download 0.394 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.352 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.348 f.17.1 F1F0 ATP synthase subunit C
View Download 0.318 a.24.17 Group V grass pollen allergen
View Download 0.298 a.7.1 Spectrin repeat
View Download 0.295 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.290 e.37.1 Bifunctional dehydrogenase/ferrochelatase Met8p, dimerisation and C-terminal domains
View Download 0.287 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.283 a.59.1 PAH2 domain
View Download 0.281 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.251 c.23.1 CheY-like
View Download 0.248 d.58.4 Dimeric alpha+beta barrel
View Download 0.219 a.138.1 Multiheme cytochromes
View Download 0.203 c.47.1 Thioredoxin-like
View Download 0.201 d.52.3 Prokaryotic type KH domain (KH-domain type II)

Predicted functions:

Term Confidence Notes
nucleic acid binding 3.16043509094686 bayes_pls_golite062009
binding 2.45816542782438 bayes_pls_golite062009
RNA binding 2.12977287614929 bayes_pls_golite062009
protein binding 1.45646458884073 bayes_pls_golite062009
transporter activity 1.17508255371693 bayes_pls_golite062009
transmembrane transporter activity 1.076425286008 bayes_pls_golite062009
mRNA binding 1.01590992981116 bayes_pls_golite062009
ligase activity 0.839455841912248 bayes_pls_golite062009
hydrolase activity 0.651922400349676 bayes_pls_golite062009
substrate-specific transporter activity 0.550646307051285 bayes_pls_golite062009
transcription regulator activity 0.502017879414539 bayes_pls_golite062009
DNA binding 0.393909838101373 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.30461161014793 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [293-780]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGKKVNTLSY SSKRIGELNE EIHEKQADWA SNDRQPACFI QFETQLEAQR CYQSVEAILG  60
   61 KKNFGKRLIG YSPEDVNWGS MRLSSKERHS RRAVANTIMV LLIIFWAFPV AVVGIISNVN 120
  121 FLTDKVPFLR FINNMPTFLM GVITGLLPTI ALVVLMSLVP PFIVMLGKLS GCVTRQETDL 180
  181 YSQAWYYAFA VIQIFLVVTA TSSASSTVDS IIDRPRSAMT LLANNLPKAS NFYIMYFILK 240
  241 GLTGPTWTIL QAVNLLLSKV LGRVLDSTPR QKWNRYNTLA TPRMGIVYPG IEILVCIYIC 300
  301 YSIIAPILLF FSTVMLTLLY VAYLYNLNYV FGFSFDLKGR NYPRALFQIF VGIYLSEVCL 360
  361 LGLFIMAKTW GPLVLEVFWI VVTALAHIYM KRKFIPLFDA VPLSAIRHAR GEPGYSYPTS 420
  421 DLGLQEIKDI ADEMKGKYEQ DNTHGILTPV TKDDLKKANL IPDNDGSSEN GTPSNPFESG 480
  481 SERASLSG

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 228.207608
Match: PF02714
Description: Domain of unknown function DUF221

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [781-991]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNAESDSIKK LNDTVIKKSS TLSSSTKDNN ESTFVPEGEK FRKFHYSDVE ALRNKRPYDE  60
   61 DDHSKHGPEG AVPVNADAGV IYSDPAAVMK EPQAFPPDVL ETNTWTRRIL QFFNPRRSYP 120
  121 FDSVRMRFPL VFNTSIEYDE EYLSSAYTDP CVREKDPIVW CCKDPLGVSK QQIQEARSNG 180
  181 LDVRDDFTRY DEKGKVIFTY NPPDYEPEAK K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [714-775]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGLQEIKDIA DEMKGKYEQD NTHGILTPVT KDDLKKANLI PDNDGSSENG TPSNPFESGS  60
   61 ER

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [776-832]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASLSGSNAES DSIKKLNDTV IKKSSTLSSS TKDNNESTFV PEGEKFRKFH YSDVEAL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [833-991]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNKRPYDEDD HSKHGPEGAV PVNADAGVIY SDPAAVMKEP QAFPPDVLET NTWTRRILQF  60
   61 FNPRRSYPFD SVRMRFPLVF NTSIEYDEEY LSSAYTDPCV REKDPIVWCC KDPLGVSKQQ 120
  121 IQEARSNGLD VRDDFTRYDE KGKVIFTYNP PDYEPEAKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle