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View Structure Prediction Details

Protein: ABZ1
Organism: Saccharomyces cerevisiae
Length: 787 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ABZ1.

Description E-value Query
Range
Subject
Range
ABZ1 - Para-aminobenzoate (PABA) synthase, has similarity to Escherichia coli PABA synthase components PabA...
PABS_YEAST - Aminodeoxychorismate synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ABZ1 PE=1 ...
0.0 [1..787] [1..787]
gi|17132576, gi|... - gi|17230935|ref|NP_487483.1| p-aminobenzoic acid synthase [Nostoc sp. PCC 7120], gi|17132576|dbj|BAB...
gi|25291359 - pir||AD2236 p-aminobenzoic acid synthase [imported] - Nostoc sp. (strain PCC 7120)
0.0 [13..787] [2..691]
gi|12231159 - gi|12231159|emb|CAC22117.1| PABA synthase [Streptomyces griseus]
0.0 [15..786] [1..689]
gi|1575336 - gi|1575336|gb|AAC44866.1| PapA
0.0 [16..786] [5..699]
gi|9621911 - gi|9621911|gb|AAF89583.1|AF166096_1 para-aminobenzoic acid synthetase [Coprinus cinereus]
0.0 [13..786] [4..735]
gi|710438 - gi|710438|gb|AAB30312.1| p-aminobenzoic acid synthase [Streptomyces venezuelae]
0.0 [15..786] [1..660]

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Predicted Domain #1
Region A:
Residues: [1-249]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSDTIDTKQ QQQQLHVLFI DSYDSFTYNV VRLIEQQTDI SPGVNAVHVT TVHSDTFQSM  60
   61 DQLLPLLPLF DAIVVGPGPG NPNNGAQDMG IISELFENAN GKLDEVPILG ICLGFQAMCL 120
  121 AQGADVSELN TIKHGQVYEM HLNDAARACG LFSGYPDTFK STRYHSLHVN AEGIDTLLPL 180
  181 CTTEDENGIL LMSAQTKNKP WFGVQYHPES CCSELGGLLV SNFLKLSFIN NVKTGRWEKK 240
  241 KLNGEFSDI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 257.855515
Match: 1qdlB_
Description: Anthranilate synthase GAT subunit, TrpG
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
anthranilate synthase activity 9.07528926783927 bayes_pls_golite062009
oxo-acid-lyase activity 7.16633518631507 bayes_pls_golite062009
4-amino-4-deoxychorismate synthase activity 4.48164623771604 bayes_pls_golite062009
indole-3-glycerol-phosphate synthase activity 4.14261580175621 bayes_pls_golite062009
nucleic acid binding 1.7339517212315 bayes_pls_golite062009
ligase activity 1.70348758031146 bayes_pls_golite062009
catalytic activity 1.30391542469987 bayes_pls_golite062009
binding 1.22860407524238 bayes_pls_golite062009
transferase activity, transferring pentosyl groups 1.01721974200042 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 0.774587372455935 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.628648036096965 bayes_pls_golite062009
imidazoleglycerol-phosphate synthase activity 0.270391651600004 bayes_pls_golite062009
carbon-carbon lyase activity 0.0769356405014503 bayes_pls_golite062009
protein binding 0.0152024556625711 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [250-787]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSRLDRTIDR DPIYKVKEKY PKGEDTTYVK QFEVSEDPKL TFEICNIIRE EKFVMSSSVI  60
   61 SENTGEWSII ALPNSASQVF THYGAMKKTT VHYWQDSEIS YTLLKKCLDG QDSDLPGSLE 120
  121 VIHEDKSQFW ITLGKFMENK IIDNHREIPF IGGLVGILGY EIGQYIACGR CNDDENSLVP 180
  181 DAKLVFINNS IVINHKQGKL YCISLDNTFP VALEQSLRDS FVRKKNIKQS LSWPKYLPEE 240
  241 IDFIITMPDK LDYAKAFKKC QDYMHKGDSY EMCLTTQTKV VPSAVIEPWR IFQTLVQRNP 300
  301 APFSSFFEFK DIIPRQDETP PVLCFLSTSP ERFLKWDADT CELRPIKGTV KKGPQMNLAK 360
  361 ATRILKTPKE FGENLMILDL IRNDLYELVP DVRVEEFMSV QEYATVYQLV SVVKAHGLTS 420
  421 ASKKTRYSGI DVLKHSLPPG SMTGAPKKIT VQLLQDKIES KLNKHVNGGA RGVYSGVTGY 480
  481 WSVNSNGDWS VNIRCMYSYN GGTSWQLGAG GAITVLSTLD GELEEMYNKL ESNLQIFM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 481.457575
Match: 1k0eA_
Description: P-aminobenzoate synthase component I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
anthranilate synthase activity 11.4918303265177 bayes_pls_golite062009
4-amino-4-deoxychorismate synthase activity 9.91522831720207 bayes_pls_golite062009
oxo-acid-lyase activity 9.57649905871948 bayes_pls_golite062009
carbon-carbon lyase activity 2.42362294309332 bayes_pls_golite062009
catalytic activity 2.11110806828104 bayes_pls_golite062009
binding 1.73874372115438 bayes_pls_golite062009
lyase activity 0.454734323696838 bayes_pls_golite062009
protein binding 0.323833479841771 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle