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View Structure Prediction Details

Protein: HXT14
Organism: Saccharomyces cerevisiae
Length: 540 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HXT14.

Description E-value Query
Range
Subject
Range
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1
0.0 [4..538] [12..528]
gi|171554 - gi|171554|gb|AAA34624.1| galactose permease
0.0 [1..538] [10..535]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..538] [7..529]
GTR3_CANLF - Solute carrier family 2, facilitated glucose transporter member 3 OS=Canis lupus familiaris GN=SLC2A...
0.0 [54..540] [4..468]
GTR3_SHEEP - Solute carrier family 2, facilitated glucose transporter member 3 OS=Ovis aries GN=SLC2A3 PE=2 SV=1
0.0 [55..540] [5..468]

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Predicted Domain #1
Region A:
Residues: [1-264]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAQIPYQHS SGYISHFHNN ELDAGRGRDY NVTIKYLDDK EENIEGQAAK ISHNASLHIP  60
   61 VLLCLVISLG GFIFGWDIGT IGGMTNMVSF QEKFGTTNII HDDETIFVST KKLTDLQIGL 120
  121 IISIFNISCG VGALTLSKIG DWIGRKGGIW FALVVYCIGI TIQILSYGRW YFLTLGRAVT 180
  181 GIGVGVTTVL VPMFLSENSP LKIRGSMVST YQLIVTFGIL MGNILNFICE RCYKDPTQNI 240
  241 AWQLPLFLGY IWAIIIGMSL VYVP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [310-526]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNEETNNESK KQSLVKRNTF EFIMGKPKLW LRLIIGMMIM AFQQLSGINY FFYYGTSVFK  60
   61 GVGIKDPYIT SIILSSVNFL STILGIYYVE KWGHKTCLLY GSTNLLFYMM TYATVGTFGR 120
  121 ETDFSNIVLI IVTCCFIFWF AITLGPVTFV LVSELFPLRT RAISMAICTF INWMFNFLIS 180
  181 LLTPMIVSKI DFKLGYIFAA CLLALIIFSW ILVPETR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 463.0103
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted Domain #2
Region A:
Residues: [265-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESPQYLAKIK NDVPSAKYSF ARMNGIPATD SMVIEFIDDL LENNY

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [527-540]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKNEQEINKI FEPE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 463.0103
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted functions:

Term Confidence Notes
glycerol transmembrane transporter activity 7.11654923455995 bayes_pls_golite062009
alcohol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
polyol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity 5.74077413704789 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 3.3746965264994 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 3.3746965264994 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 2.63293544825311 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
binding 1.89539096965643 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
sugar binding 0.285073104957756 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle