Protein: | RAD50 |
Organism: | Saccharomyces cerevisiae |
Length: | 1312 amino acids |
Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAD50.
Description | E-value | Query Range |
Subject Range |
|
0.0 | [74..1203] | [734..1847] |
|
0.0 | [74..1200] | [737..1847] |
|
0.0 | [85..1203] | [743..1845] |
|
0.0 | [84..1203] | [739..1845] |
|
0.0 | [74..1190] | [733..1833] |
|
0.0 | [74..1203] | [737..1850] |
Region A: Residues: [1-56] |
1 11 21 31 41 51 | | | | | | 1 MSAIYKLSIQ GIRSFDSNDR ETIEFGKPLT LIVGMNGSGK TTIIECLKYA TTGDLP |
Detection Method: | |
Confidence: | 2.39794 |
Match: | 1f2tA_ |
Description: | Rad50 |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [57-404] |
1 11 21 31 41 51 | | | | | | 1 PNSKGGVFIH DPKITGEKDI RAQVKLAFTS ANGLNMIVTR NIQLLMKKTT TTFKTLEGQL 60 61 VAINNSGDRS TLSTRSLELD AQVPLYLGVP KAILEYVIFC HQEDSLWPLS EPSNLKKKFD 120 121 EIFQAMKFTK ALDNLKSIKK DMSVDIKLLK QSVEHLKLDK DRSKAMKLNI HQLQTKIDQY 180 181 NEEVSEIESQ LNEITEKSDK LFKSNQDFQK ILSKVENLKN TKLSISDQVK RLSNSIDILD 240 241 LSKPDLQNLL ANFSKVLMDK NNQLRDLETD ISSLKDRQSS LQSLSNSLIR RQGELEAGKE 300 301 TYEKNRNHLS SLKEAFQHKF QGLSNIENSD MAQVNHEMSQ FKAFISQD |
Detection Method: | |
Confidence: | 78.228787 |
Match: | 1i84S_ |
Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [405-501] |
1 11 21 31 41 51 | | | | | | 1 LTDTIDQFAK DIQLKETNLS DLIKSITVDS QNLEYNKKDR SKLIHDSEEL AEKLKSFKSL 60 61 STQDSLNHEL ENLKTYKEKL QSWESENIIP KLNQKIE |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [502-610] |
1 11 21 31 41 51 | | | | | | 1 EKNNEMIILE NQIEKFQDRI MKTNQQADLY AKLGLIKKSI NTKLDELQKI TEKLQNDSRI 60 61 RQVFPLTQEF QRADLEMDFQ KLFINMQKNI AINNKKMHEL DRRYTNALY |
Detection Method: | |
Confidence: | 9.69897 |
Match: | 2tmaA_ |
Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
Term | Confidence | Notes |
transcription regulator activity | 3.33295639088462 | bayes_pls_golite062009 |
DNA binding | 3.24326474452285 | bayes_pls_golite062009 |
nucleic acid binding | 3.08466758182729 | bayes_pls_golite062009 |
binding | 2.82931587763241 | bayes_pls_golite062009 |
transcription factor activity | 2.60119592373341 | bayes_pls_golite062009 |
chromatin binding | 1.68308196781423 | bayes_pls_golite062009 |
sequence-specific DNA binding | 1.49672337781081 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 1.27509072978642 | bayes_pls_golite062009 |
telomeric DNA binding | 1.18912537020579 | bayes_pls_golite062009 |
transcription repressor activity | 0.92388271789346 | bayes_pls_golite062009 |
transcription activator activity | 0.76577083878065 | bayes_pls_golite062009 |
protein binding | 0.730593483550931 | bayes_pls_golite062009 |
structure-specific DNA binding | 0.576650348476301 | bayes_pls_golite062009 |
transcription factor binding | 0.42980456622574 | bayes_pls_golite062009 |
hydrolase activity | 0.168066467681021 | bayes_pls_golite062009 |
specific RNA polymerase II transcription factor activity | 0.10360223465653 | bayes_pls_golite062009 |
histone binding | 0.0391625783266718 | bayes_pls_golite062009 |
double-stranded DNA binding | 0.0277518020584662 | bayes_pls_golite062009 |
Region A: Residues: [611-690] |
1 11 21 31 41 51 | | | | | | 1 NLNTIEKDLQ DNQKSKEKVI QLLSENLPED CTIDEYNDVL EETELSYKTA LENLKMHQTT 60 61 LEFNRKALEI AERDSCCYLC |
Detection Method: | |
Confidence: | 9.69897 |
Match: | 2tmaA_ |
Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [691-752] |
1 11 21 31 41 51 | | | | | | 1 SRKFENESFK SKLLQELKTK TDANFEKTLK DTVQNEKEYL HSLRLLEKHI ITLNSINEKI 60 61 DN |
Detection Method: | |
Confidence: | 9.69897 |
Match: | 2tmaA_ |
Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [753-828] |
1 11 21 31 41 51 | | | | | | 1 SQKCLEKAKE ETKTSKSKLD ELEVDSTKLK DEKELAESEI RPLIEKFTYL EKELKDLENS 60 61 SKTISEELSI YNTSED |
Detection Method: | |
Confidence: | 9.69897 |
Match: | 2tmaA_ |
Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [829-1135] |
1 11 21 31 41 51 | | | | | | 1 GIQTVDELRD QQRKMNDSLR ELRKTISDLQ MEKDEKVREN SRMINLIKEK ELTVSEIESS 60 61 LTQKQNIDDS IRSKRENIND IDSRVKELEA RIISLKNKKD EAQSVLDKVK NERDIQVRNK 120 121 QKTVADINRL IDRFQTIYNE VVDFEAKGFD ELQTTIKELE LNKAQMLELK EQLDLKSNEV 180 181 NEEKRKLADS NNEEKNLKQN LELIELKSQL QHIESEISRL DVQNAEAERD KYQEESLRLR 240 241 TRFEKLSSEN AGKLGEMKQL QNQIDSLTHQ LRTDYKDIEK NYHKEWVELQ TRSFVTDDID 300 301 VYSKALD |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [1136-1229] |
1 11 21 31 41 51 | | | | | | 1 SAIMKYHGLK MQDINRIIDE LWKRTYSGTD IDTIKIRSDE VSSTVKGKSY NYRVVMYKQD 60 61 VELDMRGRCS AGQKVLASII IRLALSETFG ANCG |
Detection Method: | |
Confidence: | 38.440336 |
Match: | 1f2tB_ |
Description: | CRYSTAL STRUCTURE OF ATP-FREE RAD50 ABC-ATPASE |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [1230-1312] |
1 11 21 31 41 51 | | | | | | 1 VIALDEPTTN LDEENIESLA KSLHNIINMR RHQKNFQLIV ITHDEKFLGH MNAAAFTDHF 60 61 FKVKRDDRQK SQIEWVDINR VTY |
Detection Method: | |
Confidence: | 38.440336 |
Match: | 1f2tB_ |
Description: | CRYSTAL STRUCTURE OF ATP-FREE RAD50 ABC-ATPASE |
Matching Structure (courtesy of the PDB): |