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View Structure Prediction Details

Protein: PDR16
Organism: Saccharomyces cerevisiae
Length: 351 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PDR16.

Description E-value Query
Range
Subject
Range
PDR16 - Phosphatidylinositol transfer protein (PITP) controlled by the multiple drug resistance regulator Pd...
PDR16_YEAST - Phosphatidylinositol transfer protein PDR16 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)...
gi|190409202 - gi|190409202|gb|EDV12467.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
gi|207341877 - gi|207341877|gb|EDZ69815.1| YNL231Cp-like protein [Saccharomyces cerevisiae AWRI1631]
1.0E-78 [1..351] [1..351]
SFH3_ARATH - Phosphatidylinositol/phosphatidylcholine transfer protein SFH3 OS=Arabidopsis thaliana GN=SFH3 PE=2 ...
1.0E-69 [10..326] [18..339]
gi|14486705 - gi|14486705|gb|AAK63247.1|AF367433_1 phosphatidylinositol transfer-like protein III [Lotus japonicus...
5.0E-68 [3..323] [22..351]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-65 [3..325] [22..354]

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Predicted Domain #1
Region A:
Residues: [1-57]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKRFSKKKE APEDPKNLIN IDKPIKELPA SIAIPKEKPL TGEQQKMYDE VLKHFSN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [113-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AWRREFGISH LGEEHGDKIT ADLVAVENES GKQVILGYEN DARPILYLKP GRQNTKTSHR  60
   61 QVQHLVFMLE RVIDFMPAGQ DSLALLIDFK DYPDVPKVPG NSKIPPIGVG KEVLHILQTH 120
  121 YPERLGKALL TNIPWLAWTF LKLIHPFIDP LTREKLVFDE PFVKYVPKNE LDSLYGGDLK 180
  181 FKYNHDVYWP ALVETAREKR DHYFKRFQSF GGIVGLSEVD LRGTHEKLLY PVKSESSTV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 139.68867
Match: 1aua__
Description: N-terminal domain of phosphatidylinositol transfer protein sec14p; C-terminal domain of phosphatidylinositol transfer protein sec14p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phospholipid transporter activity 4.82372291869245 bayes_pls_golite062009
lipid transporter activity 3.44932625048477 bayes_pls_golite062009
phosphatidylinositol transporter activity 3.08477039249457 bayes_pls_golite062009
binding 1.41701101210975 bayes_pls_golite062009
transporter activity 1.00447017621654 bayes_pls_golite062009
vitamin binding 0.87942237566918 bayes_pls_golite062009
substrate-specific transporter activity 0.658164745879483 bayes_pls_golite062009
vitamin E binding 0.425230876259729 bayes_pls_golite062009
protein binding 0.132818074687599 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [58-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDLKVYTSEK NKSEDDLKPL EEEEKAWLTR ECFLRYLRAT KWVLKDCIDR ITMTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 139.68867
Match: 1aua__
Description: N-terminal domain of phosphatidylinositol transfer protein sec14p; C-terminal domain of phosphatidylinositol transfer protein sec14p
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle