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View Structure Prediction Details

Protein: IMP4
Organism: Saccharomyces cerevisiae
Length: 290 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IMP4.

Description E-value Query
Range
Subject
Range
gi|190409064 - gi|190409064|gb|EDV12329.1| U3 small nucleolar ribonucleoprotein protein IMP4 [Saccharomyces cerevis...
IMP4_YEAST - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / ...
gi|207341687 - gi|207341687|gb|EDZ69673.1| YNL075Wp-like protein [Saccharomyces cerevisiae AWRI1631]
IMP4 - Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10...
7.0E-90 [1..290] [1..290]
gi|12850634, gi|... - gi|30519917|ref|NP_848716.1| U3 snoRNP protein 4 homolog [Mus musculus], gi|12850634|dbj|BAB28797.1|...
3.0E-82 [1..290] [1..288]
IMP4 - IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
gi|124000169, gi... - gi|157929232|gb|ABW03901.1| IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) [synthetic c...
2.0E-81 [1..290] [1..288]
CE18464 - status:Confirmed UniProt:O62518 protein_id:CAB05841.1
3.0E-81 [1..290] [1..283]
gi|32405940, gi|... - gi|32405940|ref|XP_323583.1| probable component of the U3 small nucleolar ribonucleoprotein [MIPS] [...
gi|85101912 - gi|85101912|ref|XP_961234.1| U3 small nucleolar ribonucleoprotein protein IMP4 [Neurospora crassa OR...
7.0E-81 [1..289] [1..294]
IMP4_SCHPO - U3 small nucleolar ribonucleoprotein protein imp4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24...
SPAC19A8.07c - U3 snoRNP-associated protein Imp4
4.0E-80 [1..290] [1..287]
gi|19577368, gi|... - gi|42820709|emb|CAF32022.1| imp4 protein, putative [Aspergillus fumigatus], gi|19577368|emb|CAD28449...
gi|66850312, gi|... - gi|70995844|ref|XP_752677.1| U3 small nucleolar ribonucleoprotein protein IMP4 [Aspergillus fumigatu...
2.0E-79 [1..290] [1..299]
gi|20260206, gi|... - pir||H96662 hypothetical protein T12P18.20 [imported] - Arabidopsis thaliana, gi|21593725|gb|AAM656...
6.0E-77 [1..290] [1..292]
gi|4262378 - gi|4262378|gb|AAD14602.1| stage specific peptide 24 [Trypanosoma cruzi]
7.0E-77 [1..290] [1..287]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRRQARERR EYLYRKAQEL QDSQLQQKRQ IIKQALAQGK PLPKELAEDE SLQKDFRYDQ  60
   61 SLKESEEADD LQVDDEYAAT SGIMDPR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [88-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IIVTTSRDPS TRLSQFAKEI KLLFPNAVRL NRGNYVMPNL VDACKKSGTT DLVVLHEHRG  60
   61 VPTSLTISHF PHGPTAQFSL HNVVMRHDII NAGNQSEVNP HLIFDNFTTA LGKRVVCILK 120
  121 HLFNAGPKKD SERVITFANR GDFISVRQHV YVRTREGVEI AEVGPRFEMR LFELRLGTLE 180
  181 NKDADVEWQL RRFIRTANKK DYL

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 87.017729
Match: PF01945
Description: No description for PF01945 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
aminoacyl-tRNA ligase activity 3.58650371779212 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 3.58624422951947 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 3.58624422951947 bayes_pls_golite062009
ligase activity 2.71574082295198 bayes_pls_golite062009
proline-tRNA ligase activity 2.35871952544841 bayes_pls_golite062009
binding 1.73857064375258 bayes_pls_golite062009
catalytic activity 0.902495165806215 bayes_pls_golite062009
protein binding 0.358563180490135 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [177-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INAGNQSEVN PHLIFDNFTT ALGKRVVCIL KHLFNAGPKK DSERVITFAN RGDFISVRQH  60
   61 VYVRTREGVE IAEVGPRFEM RLFELRLGTL ENKDADVEWQ LRRFIRTANK KDYL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.84
Match: 1w94A
Description: Crystal Structure of Mil (Mth680), an archaeal Imp4-like protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle