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View Structure Prediction Details

Protein: SSO2
Organism: Saccharomyces cerevisiae
Length: 295 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SSO2.

Description E-value Query
Range		 Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 4.0E-49 [6..292] [10..295]
STX1A_MOUSE - Syntaxin-1A OS=Mus musculus GN=Stx1a PE=1 SV=3
 2.0E-48 [7..292] [1..285]
STX1B_MOUSE - Syntaxin-1B OS=Mus musculus GN=Stx1b PE=1 SV=1
gi|251471 - gi|251471|gb|AAB22526.1| syntaxin, P35B [rats, brain, Peptide, 288 aa]
ENSCJAT00000005845 - null
gi|114662156 - gi|114662156|ref|XP_001145497.1| PREDICTED: similar to syntaxin B [Pan troglodytes]
STX1B - syntaxin 1B
STX1B_RAT - Syntaxin-1B OS=Rattus norvegicus GN=Stx1b PE=1 SV=1
 1.0E-47 [7..293] [1..285]
gi|7595847, gi|7... - gi|7595847|gb|AAF64478.1| syntaxin 1A [Macaca mulatta], gi|74136291|ref|NP_001028037.1| syntaxin 1B ...
 2.0E-47 [7..292] [1..285]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
 2.0E-47 [7..293] [1..285]
gi|18859443, gi|... - gi|7107406|gb|AAF36403.1|AF229154_1 syntaxin 1B [Danio rerio], gi|18859443|ref|NP_571598.1| syntaxin...
 3.0E-47 [7..293] [1..285]
STX1A_BOVIN - Syntaxin-1A OS=Bos taurus GN=STX1A PE=1 SV=1
 5.0E-47 [7..282] [1..280]

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Predicted Domain #1
Region A:
Residues: [1-144] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNANPYENN NPYAENYEMQ EDLNNAPTGH SDGSDDFVAF MNKINSINAN LSRYENIINQ  60
   61 IDAQHKDLLT QVSEEQEMEL RRSLDDYISQ ATDLQYQLKA DIKDAQRDGL HDSNKQAQAE 120
  121 NCRQKFLKLI QDYRIIDSNY KEES

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [200-295] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RHQELLKLEK TMAELTQLFN DMEELVIEQQ ENVDVIDKNV EDAQQDVEQG VGHTNKAVKS  60
   61 ARKARKNKIR CLIICFIIFA IVVVVVVVPS VVETRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 699.30103
Match: 1fioA_
Description: Sso1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphatidic acid binding 8.51970136264329 bayes_pls_golite062009
SNAP receptor activity 3.50393203740159 bayes_pls_golite062009
binding 2.33192450173199 bayes_pls_golite062009
protein transporter activity 1.74973029929612 bayes_pls_golite062009
transporter activity 1.74189664015129 bayes_pls_golite062009
protein binding 1.61683263008775 bayes_pls_golite062009
excitatory extracellular ligand-gated ion channel activity 1.54368755758216 bayes_pls_golite062009
extracellular ligand-gated ion channel activity 1.54368755758216 bayes_pls_golite062009
substrate-specific transporter activity 1.49085442233849 bayes_pls_golite062009
transmembrane transporter activity 1.13101548288086 bayes_pls_golite062009
SNARE binding 0.71459772253941 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.643064875848901 bayes_pls_golite062009
gated channel activity 0.621670335227137 bayes_pls_golite062009
ligand-gated ion channel activity 0.41937155561589 bayes_pls_golite062009
ligand-gated channel activity 0.41937155561589 bayes_pls_golite062009
extracellular-glutamate-gated ion channel activity 0.394485000881621 bayes_pls_golite062009
ion transmembrane transporter activity 0.370484918396857 bayes_pls_golite062009
calcium channel inhibitor activity 0.24104982008887 bayes_pls_golite062009
channel activity 0.0647076360772156 bayes_pls_golite062009
passive transmembrane transporter activity 0.0647076360772156 bayes_pls_golite062009
substrate-specific channel activity 0.0435980899803177 bayes_pls_golite062009
phospholipid binding 0.0172309833091902 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [145-199] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEQAKRQYTI IQPEATDEEV EAAINDVNGQ QIFSQALLNA NRRGEAKTAL AEVQA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 699.30103
Match: 1fioA_
Description: Sso1
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle