YRC Public Data Repository - Protein Structure Prediction

Protein:	YMR155W
Organism:	Saccharomyces cerevisiae
Length:	547 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YMR155W.

Description	E-value	Query Range	Subject Range
YM30_YEAST - Uncharacterized membrane protein YMR155W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN... YMR155W - Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two...	3.0E-70	[1..547]	[1..547]
gi\|20259958, gi\|... - gi\|4063746\|gb\|AAC98454.1\| nodulin-like protein [Arabidopsis thaliana], pir\|\|A84681 nodulin-like prot...	1.0E-48	[17..539]	[17..547]
gi\|25498023 - pir\|\|D96902 MDR-type permease [imported] - Clostridium acetobutylicum gi\|15893318, gi\|... - gi\|15893318\|ref\|NP_346667.1\| MDR-type permease [Clostridium acetobutylicum ATCC 824], gi\|15022839\|gb...	2.0E-45	[13..512]	[2..431]
CE04864 - status:Partially_confirmed UniProt:Q22109 protein_id:AAA82406.1	2.0E-45	[12..523]	[15..540]

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Predicted Domain #1

Region A:
Residues: [1-271]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKKHQNSKM GNTNHFGHLK SFVGGNVVAL GAGTPYLFSF YAPQLLSKCH IPVSASSKLS  60
   61 FSLTIGSSLM GILAGIVVDR SPKLSCLIGS MCVFIAYLIL NLCYKHEWSS TFLISLSLVL 120
  121 IGYGSVSGFY ASVKCANTNF PQHRGTAGAF PVSLYGLSGM VFSYLCSKLF GENIEHVFIF 180
  181 LMVACGCMIL VGYFSLDIFS NAEGDDASIK EWELQKSRET DDNIVPLYEN SNDYIGSPVR 240
  241 SSSPATYETY ALSDNFQETS EFFALEDRQL S

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.522879
Match:	1lviA_
Description:	No description for 1lviA_ was found.

Predicted functions:

Term	Confidence	Notes
transporter activity	4.09176719149278	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transporter activity	3.3426261924492	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.29689809004391	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.15783210522667	bayes_pls_golite062009
ion transmembrane transporter activity	1.94035843948137	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
cation transmembrane transporter activity	1.5181741634556	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
binding	1.01584233411372	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [272-335]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRPLLSPSSP HTKYDFEDEN TSKNTVGENS AQKSMRLHVF QSLKSSTFIG YYIVLGILQG  60
   61 VGLM

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [336-547]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YIYSVGFMVQ AQVSTPPLNQ LPINAEKIQS LQVTLLSLLS FCGRLSSGPI SDFLVKKFKA  60
   61 QRLWNIVIAS LLVFLASNKI SHDFSSIEDP SLRASKSFKN ISVCSAIFGY SFGVLFGTFP 120
  121 SIVADRFGTN GYSTLWGVLT TGGVFSVSVF TDILGRDFKA NTGDDDGNCK KGVLCYSYTF 180
  181 MVTKYCAAFN LLFVLGIIGY TYYRRRATAN SL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: