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View Structure Prediction Details

Protein: STO1
Organism: Saccharomyces cerevisiae
Length: 861 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for STO1.

Description E-value Query
Range
Subject
Range
NCBP1_YEAST - Nuclear cap-binding protein complex subunit 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288...
gi|190408354 - gi|190408354|gb|EDV11619.1| protein GCR3 [Saccharomyces cerevisiae RM11-1a]
STO1 - Large subunit of the nuclear mRNA cap-binding protein complex, interacts with Npl3p to carry nuclear...
0.0 [1..861] [1..861]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [9..861] [6..858]
gi|4586403 - gi|4586403|dbj|BAA76378.1| CaGCR3 [Candida albicans]
0.0 [3..854] [5..884]
NCBP1 - nuclear cap binding protein subunit 1, 80kDa
gi|123997413, gi... - gi|157929034|gb|ABW03802.1| nuclear cap binding protein subunit 1, 80kDa [synthetic construct], gi|1...
ENSPTRT00000039143 - null
0.0 [6..824] [3..718]
Cbp80-PA, Cbp80-PB - The gene cap binding protein 80 is referred to in FlyBase by the symbol Dmel\Cbp80 (CG7035, FBgn0022...
gi|220947496 - gi|220947496|gb|ACL86291.1| Cbp80-PA [synthetic construct]
0.0 [5..824] [3..728]
NCBP1_ARATH - Nuclear cap-binding protein subunit 1 OS=Arabidopsis thaliana GN=ABH1 PE=1 SV=2
0.0 [42..812] [7..702]

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Predicted Domain #1
Region A:
Residues: [1-231]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFNRKRRGDF DEDENYRDFR PRMPKRQRIP PVVQLCKEMM PDIRTIGESV KAFEDDIKFL  60
   61 SEAIMNEYGH EDYFNNALLS TLNAVVVEQP QKQAAIALLT MVVNSKNNVA GKSIINYFFE 120
  121 ELQKWCKQTY NDEFKSTSNE TGPWNKIKLI LRFLSILSPM FLVDELINIY KSLFELSIEL 180
  181 NNLDPGNRVP LSEAIYTNTL LNIPYLFFFN RNNDGLRTKV EELLAYVEQN Y

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [259-320]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLPNVKKALI NNLEQLNELF PDWNHLLTPQ TGDEGFNDAL TLPSVDDLKS FVRLNKNFGS  60
   61 VD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1136.9897
Match: 1h6kA_
Description: CBP80, 80KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA cap binding 6.31996430626206 bayes_pls_golite062009
RNA binding 4.20683443264388 bayes_pls_golite062009
binding 3.0667965351474 bayes_pls_golite062009
structural molecule activity 2.87774614675757 bayes_pls_golite062009
nucleic acid binding 2.74745843355294 bayes_pls_golite062009
mRNA binding 2.49094746544717 bayes_pls_golite062009
transcription regulator activity 2.16673352512615 bayes_pls_golite062009
DNA binding 1.95242774903625 bayes_pls_golite062009
protein binding 1.73688475473996 bayes_pls_golite062009
transcription factor activity 1.20660383756339 bayes_pls_golite062009
translation regulator activity 1.02418717576405 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.00890624159335 bayes_pls_golite062009
translation initiation factor activity 0.83079633551839 bayes_pls_golite062009
hydrolase activity 0.42501390959416 bayes_pls_golite062009
transcription activator activity 0.160275383613705 bayes_pls_golite062009
transcription factor binding 0.0221966060394205 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [232-258]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVKTTDINLL REYNGEPPYE MVELVRV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [321-462]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SMWKTPRYAF HVYLPNSAGN FETVVPISTY AGQLFNDIII DLVESLEFNR KEVARQVITL  60
   61 DLFFKAGIFT EPGESIAQLI ATYEENPLAP TFKIEDLAIE TILGLIFKLP SVSQPFAYFY 120
  121 TLLVDICQNS PKAIAPVFGR AF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1136.9897
Match: 1h6kA_
Description: CBP80, 80KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [463-555]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RFFYSHLDSL DFELKLRYLD WFSIQMSNFN FSWKWNEWED DSIKFGKYFY NPKVNFAKNL  60
   61 IQKELRLTSN FSEVEDSLPQ EFTKYLDTSY IPR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1136.9897
Match: 1h6kA_
Description: CBP80, 80KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [556-861]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQLINYYQSL FTGYTVEEDS VRKNDLYFRQ EGVPMENTVR KILDYTHKAN NSREVTELES  60
   61 ILGELKNEYG SIISDFNRFV IILLVQAVTD SGSRSLSHAN KYINDLKEDL KTIFAKIELD 120
  121 IETKEYIIIE AVLTFWNANP QTGFLVADAF KYAGLLTSRT IFTFIFNETG LKNNGLIEAT 180
  181 AIEAVFRNLS QQISEENESG NNFEFVFERL CTIANSTIDL LDVNADEDIE IPKVNGEMDI 240
  241 DDIEDDKLDL KWKYFTVIGF IKSILRRYSH EYRELADKFI ANIDNAIPHE STRRTISNWI 300
  301 QETKEV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1136.9897
Match: 1h6kA_
Description: CBP80, 80KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle