| Protein: | MDM1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1127 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MDM1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1127] | [1..1127] |
|
|
0.0 | [23..1107] | [41..1103] |
|
|
0.0 | [7..1123] | [7..999] |
|
|
0.0 | [9..1122] | [60..1004] |
|
|
0.0 | [4..575] | [81..576] |
|
Region A: Residues: [1-80] |
1 11 21 31 41 51
| | | | | |
1 MPKFPQFRLI LVLFYLISMI QWSVITFSLG FFLNVCIFAY FVFFKSLPDL PKPQPRFVDI 60
61 VPESSNTVDV DKELKSVEGL
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.507 | a.65.1 | Annexin |
| View | Download | 0.561 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.752 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.595 | a.49.1 | C-terminal domain of B transposition protein |
| View | Download | 0.565 | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.752 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.711 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.595 | a.49.1 | C-terminal domain of B transposition protein |
| View | Download | 0.565 | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.561 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.506 | a.17.1 | p8-MTCP1 |
| View | Download | 0.452 | a.74.1 | Cyclin-like |
| View | Download | 0.448 | a.4.1 | Homeodomain-like |
| View | Download | 0.421 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.381 | d.58.26 | GHMP Kinase, C-terminal domain |
| View | Download | 0.359 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.353 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.330 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.329 | a.4.1 | Homeodomain-like |
| View | Download | 0.325 | a.4.1 | Homeodomain-like |
| View | Download | 0.323 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.321 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.315 | d.42.1 | POZ domain |
| View | Download | 0.290 | a.47.2 | t-snare proteins |
| View | Download | 0.278 | a.24.4 | Hemerythrin |
| View | Download | 0.270 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.269 | a.112.1 | Description not found. |
| View | Download | 0.269 | a.20.1 | PGBD-like |
| View | Download | 0.268 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.257 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.252 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.246 | a.77.1 | DEATH domain |
| View | Download | 0.241 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.240 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.229 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.220 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.219 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.218 | a.3.1 | Cytochrome c |
| View | Download | 0.218 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.217 | d.52.4 | YhbC-like, N-terminal domain |
| View | Download | 0.209 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.204 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.201 | a.7.6 | Ribosomal protein S20 |
|
Region A: Residues: [81-294] |
1 11 21 31 41 51
| | | | | |
1 IQDGNAQIGK ELESIVNLII KDFVQPWFTK IDKNSDAEFL KVIKWRLLQT LLVVKDKLMK 60
61 NDSASLIVLK LLPIFNKHFS TFCDAREAVL SDLTLERHKS ANIDLQIAVE FNKNYKIHKS 120
121 LSLKPNALQK EIEKSIRKTV IGLLPHLFDN DELDSLLVFT LMTEVLTTCI ISPLIFKFTD 180
181 PDSWNLRIVS LSQNYFEEKH KVHKIRRMLS KELQ
|
| Detection Method: | |
| Confidence: | 97.568636 |
| Match: | PF02194 |
| Description: | PXA domain |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [295-388] |
1 11 21 31 41 51
| | | | | |
1 DHRKVMNDVA NKDVGEPSSE KLELNAEYTG KQFEHYLNQL DSLLDLSDIK YVAYSLALKI 60
61 YQLKENEHLT KENLKYKKRL LLSLNLIESK LSFP
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.877 | 0.010 | mitochondrion inheritance | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.791 | 0.010 | mitochondrion inheritance | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.906 | 0.010 | mitochondrion inheritance | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.737 | 0.010 | mitochondrion inheritance | a.69.3 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain |
| View | Download | 0.733 | 0.010 | mitochondrion inheritance | a.29.2 | Bromodomain |
| View | Download | 0.676 | 0.010 | mitochondrion inheritance | a.118.1 | ARM repeat |
| View | Download | 0.634 | 0.010 | mitochondrion inheritance | a.46.1 | Methionine synthase domain |
| View | Download | 0.615 | 0.010 | mitochondrion inheritance | d.150.1 | 4'-phosphopantetheinyl transferase |
| View | Download | 0.614 | 0.010 | mitochondrion inheritance | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.604 | 0.010 | mitochondrion inheritance | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.600 | 0.010 | mitochondrion inheritance | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.594 | 0.010 | mitochondrion inheritance | a.112.1 | Description not found. |
| View | Download | 0.591 | 0.010 | mitochondrion inheritance | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.573 | 0.010 | mitochondrion inheritance | a.1.1 | Globin-like |
| View | Download | 0.553 | 0.010 | mitochondrion inheritance | d.58.16 | Poly(A) polymerase, C-terminal domain |
| View | Download | 0.544 | 0.010 | mitochondrion inheritance | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.539 | 0.010 | mitochondrion inheritance | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.530 | 0.010 | mitochondrion inheritance | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.530 | 0.010 | mitochondrion inheritance | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.528 | 0.010 | mitochondrion inheritance | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.516 | 0.010 | mitochondrion inheritance | a.74.1 | Cyclin-like |
| View | Download | 0.481 | 0.010 | mitochondrion inheritance | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.479 | 0.010 | mitochondrion inheritance | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.479 | 0.010 | mitochondrion inheritance | d.95.2 | Homing endonucleases |
| View | Download | 0.473 | 0.010 | mitochondrion inheritance | a.5.4 | Elongation factor TFIIS domain 2 |
| View | Download | 0.470 | 0.010 | mitochondrion inheritance | a.29.2 | Bromodomain |
| View | Download | 0.466 | 0.010 | mitochondrion inheritance | a.63.1 | Apolipophorin-III |
| View | Download | 0.454 | 0.010 | mitochondrion inheritance | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.449 | 0.010 | mitochondrion inheritance | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.437 | 0.010 | mitochondrion inheritance | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.432 | 0.010 | mitochondrion inheritance | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.428 | 0.010 | mitochondrion inheritance | a.47.2 | t-snare proteins |
| View | Download | 0.419 | 0.010 | mitochondrion inheritance | a.118.9 | ENTH/VHS domain |
| View | Download | 0.416 | 0.010 | mitochondrion inheritance | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.411 | 0.010 | mitochondrion inheritance | a.64.1 | Saposin |
| View | Download | 0.408 | 0.010 | mitochondrion inheritance | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.404 | 0.010 | mitochondrion inheritance | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.393 | 0.010 | mitochondrion inheritance | a.24.4 | Hemerythrin |
| View | Download | 0.384 | 0.010 | mitochondrion inheritance | d.26.1 | FKBP-like |
| View | Download | 0.376 | 0.010 | mitochondrion inheritance | a.23.5 | Hemolysin expression modulating protein HHA |
| View | Download | 0.371 | 0.010 | mitochondrion inheritance | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.367 | 0.010 | mitochondrion inheritance | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.359 | 0.010 | mitochondrion inheritance | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.359 | 0.010 | mitochondrion inheritance | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.353 | 0.010 | mitochondrion inheritance | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.350 | 0.010 | mitochondrion inheritance | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.341 | 0.010 | mitochondrion inheritance | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.337 | 0.010 | mitochondrion inheritance | a.24.3 | Cytochromes |
| View | Download | 0.334 | 0.010 | mitochondrion inheritance | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.330 | 0.010 | mitochondrion inheritance | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.326 | 0.010 | mitochondrion inheritance | d.87.2 | CO dehydrogenase flavoprotein C-terminal domain-like |
| View | Download | 0.319 | 0.010 | mitochondrion inheritance | a.39.1 | EF-hand |
| View | Download | 0.313 | 0.010 | mitochondrion inheritance | a.24.3 | Cytochromes |
| View | Download | 0.298 | 0.010 | mitochondrion inheritance | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.291 | 0.010 | mitochondrion inheritance | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.289 | 0.010 | mitochondrion inheritance | a.7.1 | Spectrin repeat |
| View | Download | 0.288 | 0.010 | mitochondrion inheritance | a.2.3 | Chaperone J-domain |
| View | Download | 0.288 | 0.010 | mitochondrion inheritance | a.23.3 | Methane monooxygenase hydrolase, gamma subunit |
| View | Download | 0.284 | 0.010 | mitochondrion inheritance | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.281 | 0.010 | mitochondrion inheritance | a.75.1 | Ribosomal protein S7 |
| View | Download | 0.277 | 0.010 | mitochondrion inheritance | c.102.1 | Cell-division inhibitor MinC, N-terminal domain |
| View | Download | 0.275 | 0.010 | mitochondrion inheritance | a.130.1 | Chorismate mutase II |
| View | Download | 0.273 | 0.010 | mitochondrion inheritance | a.118.16 | Testis/brain RNA-binding protein (TB-RBP) |
| View | Download | 0.267 | 0.010 | mitochondrion inheritance | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| View | Download | 0.266 | 0.010 | mitochondrion inheritance | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| View | Download | 0.261 | 0.010 | mitochondrion inheritance | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.260 | 0.010 | mitochondrion inheritance | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.257 | 0.010 | mitochondrion inheritance | a.77.1 | DEATH domain |
| View | Download | 0.253 | 0.010 | mitochondrion inheritance | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.251 | 0.010 | mitochondrion inheritance | d.110.4 | SNARE-like |
| View | Download | 0.249 | 0.010 | mitochondrion inheritance | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.249 | 0.010 | mitochondrion inheritance | a.77.1 | DEATH domain |
| View | Download | 0.249 | 0.010 | mitochondrion inheritance | d.87.2 | CO dehydrogenase flavoprotein C-terminal domain-like |
| View | Download | 0.248 | 0.010 | mitochondrion inheritance | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.246 | 0.010 | mitochondrion inheritance | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.243 | 0.010 | mitochondrion inheritance | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.241 | 0.010 | mitochondrion inheritance | a.4.1 | Homeodomain-like |
| View | Download | 0.234 | 0.010 | mitochondrion inheritance | d.58.39 | Glutamyl tRNA-reductase catalytic, N-terminal domain |
| View | Download | 0.234 | 0.010 | mitochondrion inheritance | a.126.1 | Serum albumin-like |
| View | Download | 0.232 | 0.010 | mitochondrion inheritance | a.3.1 | Cytochrome c |
| View | Download | 0.230 | 0.010 | mitochondrion inheritance | c.47.1 | Thioredoxin-like |
| View | Download | 0.225 | 0.010 | mitochondrion inheritance | a.1.1 | Globin-like |
| View | Download | 0.225 | 0.010 | mitochondrion inheritance | d.58.48 | MTH1187-like |
| View | Download | 0.224 | 0.010 | mitochondrion inheritance | d.146.1 | Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain |
| View | Download | 0.223 | 0.010 | mitochondrion inheritance | a.24.11 | Bacterial GAP domain |
| View | Download | 0.220 | 0.010 | mitochondrion inheritance | a.47.2 | t-snare proteins |
| View | Download | 0.219 | 0.010 | mitochondrion inheritance | a.2.2 | Ribosomal protein L29 (L29p) |
| View | Download | 0.217 | 0.010 | mitochondrion inheritance | a.1.1 | Globin-like |
| View | Download | 0.216 | 0.010 | mitochondrion inheritance | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.216 | 0.010 | mitochondrion inheritance | c.55.3 | Ribonuclease H-like |
| View | Download | 0.216 | 0.010 | mitochondrion inheritance | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.215 | 0.010 | mitochondrion inheritance | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.215 | 0.010 | mitochondrion inheritance | d.58.26 | GHMP Kinase, C-terminal domain |
| View | Download | 0.212 | 0.010 | mitochondrion inheritance | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.209 | 0.010 | mitochondrion inheritance | a.5.3 | N-terminal domain of phosphatidylinositol transfer protein sec14p |
| View | Download | 0.206 | 0.010 | mitochondrion inheritance | a.74.1 | Cyclin-like |
| View | Download | 0.206 | 0.010 | mitochondrion inheritance | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.203 | 0.010 | mitochondrion inheritance | d.13.1 | HIT-like |
| View | Download | 0.202 | 0.010 | mitochondrion inheritance | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
|
Region A: Residues: [389-607] |
1 11 21 31 41 51
| | | | | |
1 GSEIDTASKK LAREANYPDL NMDNGIVLKE MASFLTSITL KDIVDDSEFL PFFESFLGSV 60
61 PETQGSTFLE YSQTIESFKN PLEDATSEDI ISGYSGISTM QLQEISSKFF HNNNLQNMKL 120
121 LDEGLVKNII LFRNSFQINN DEDTFILARK SVLLLQTEAI KYLDDRFLPL FKKTPSFLKM 180
181 LSTSHIISTD IYAHFLSRIG GVNNPEQNKI IKDNVKTDF
|
| Detection Method: | |
| Confidence: | 12.29 |
| Match: | 1agrE |
| Description: | Regulator of G-protein signalling 4, RGS4 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 1.74066926539061 | bayes_pls_golite062009 |
| protein binding | 1.46874099847386 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.751540543950607 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.726313915060022 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.619424511001805 | bayes_pls_golite062009 |
| enzyme activator activity | 0.423538625413241 | bayes_pls_golite062009 |
| GTPase activator activity | 0.380332469241193 | bayes_pls_golite062009 |
| calmodulin binding | 0.144645492942361 | bayes_pls_golite062009 |
|
Region A: Residues: [608-696] |
1 11 21 31 41 51
| | | | | |
1 MNPVRIFANP GITDALDNIV NGSGSKPHKS RISSNPRYSQ LFGSENDNIF KDKLFDDEND 60
61 NTSEISVVED QLDHPRNMEK VSVSSGNSG
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.392 | 0.882 | mitochondrion inheritance | a.39.1 | EF-hand |
| View | Download | 0.463 | 0.882 | mitochondrion inheritance | c.47.1 | Thioredoxin-like |
| View | Download | 0.255 | 0.882 | mitochondrion inheritance | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.311 | 0.882 | mitochondrion inheritance | a.39.1 | EF-hand |
| View | Download | 0.291 | 0.882 | mitochondrion inheritance | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.235 | 0.882 | mitochondrion inheritance | a.163.1 | Crustacean CHH/MIH/GIH neurohormone |
| View | Download | 0.215 | 0.882 | mitochondrion inheritance | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.202 | 0.882 | mitochondrion inheritance | a.118.11 | Cytochrome c oxidase subunit E |
|
Region A: Residues: [697-920] |
1 11 21 31 41 51
| | | | | |
1 LNPSQFYGSN NFRDNIASLT ISIDQIEKEL ELLRHLILKA DLTNNQMQLK ILKKSQRTLL 60
61 KELEMKELLK QQYMVQENGN SLFRKTKIYI RSYFSENSSN GLKEITYYII NIHHFNNGQV 120
121 SSWDMARRYN EFFELNTYLK KNFRDLMRQL QDLFPSKVKM SLKYHVTKTL LYEERKQKLE 180
181 KYLRELLSIS EICEDNIFRR FLTDPTPFKL NKEYMHDDIL EEPL
|
| Detection Method: | |
| Confidence: | 22.154902 |
| Match: | 1h6hA_ |
| Description: | p40phox NADPH oxidase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [921-1127] |
1 11 21 31 41 51
| | | | | |
1 HEPIGSSNST SNSSSVVDLQ SSEDGGELNF YEDERHFFTD SGYPFYSQNK SFVKQICDLF 60
61 ISLFALNKAN AGWLRGRAII TVLQQLLGST IEKYIKVSIQ KLRSEDQVFE AIVTFKNMLW 120
121 GDNGLFERKR NETAEATRSE GERLRTEQLA LTSLQRLFAD TCGRVVGLRD SHEAAGRVHA 180
181 MLQNPYLNAS LLLEALDAIL LDIICND
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
